CA2244245C - Composes de dihydrobenzofurane utilise comme agents anti-inflammatoires - Google Patents

Composes de dihydrobenzofurane utilise comme agents anti-inflammatoires Download PDF

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Publication number
CA2244245C
CA2244245C CA002244245A CA2244245A CA2244245C CA 2244245 C CA2244245 C CA 2244245C CA 002244245 A CA002244245 A CA 002244245A CA 2244245 A CA2244245 A CA 2244245A CA 2244245 C CA2244245 C CA 2244245C
Authority
CA
Canada
Prior art keywords
compound
group
hydrogen
alkyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002244245A
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English (en)
Other versions
CA2244245A1 (fr
Inventor
Laurence Ichih Wu
John Michael Janusz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanderbilt University
Original Assignee
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/595,113 external-priority patent/US5750543A/en
Application filed by Vanderbilt University filed Critical Vanderbilt University
Publication of CA2244245A1 publication Critical patent/CA2244245A1/fr
Application granted granted Critical
Publication of CA2244245C publication Critical patent/CA2244245C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne un composé ayant la structure (I) dans laquelle (a) n vaut de 1 à environ 3; (b) X est sélectionné dans le groupe constitué par O, S, SO ou SO2; (c) Y représente indépendamment hydrogène ou alkyle droit, ramifié ou cyclique possédant de 1 à environ 4 atomes de carbone, ou bien les Y sont reliés afin de former un noyau alcanyle possédant d'environ 3 à environ 7 atomes; (d) Z représente hydrogène ou alkyle droit, ramifié ou cyclique possédant de 3 à environ 10 atomes autres que l'hydrogène; (e) W représente O ou S; et (f) Het est un groupe hétéroaryle comprenant un ou plusieurs noyaux, chaque noyau contenant d'environ 5 à environ 6 atomes autres que l'hydrogène, ce groupe contenant au moins 1 hétéroatome sélectionné à partir de O, N ou S. L' invention concerne des compositions pharmaceutiques comprenant ces composés ainsi que des procédés de traitement de l'inflammation ou de la douleur au moyen de ces composés.
CA002244245A 1996-02-01 1997-01-30 Composes de dihydrobenzofurane utilise comme agents anti-inflammatoires Expired - Fee Related CA2244245C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/595,113 US5750543A (en) 1996-02-01 1996-02-01 Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US08/595,113 1996-02-01
PCT/US1997/001310 WO1997028144A1 (fr) 1996-02-01 1997-01-30 Composes de dihydrobenzofurane utilise comme agents anti-inflammatoires

Publications (2)

Publication Number Publication Date
CA2244245A1 CA2244245A1 (fr) 1997-08-07
CA2244245C true CA2244245C (fr) 2005-11-29

Family

ID=35520643

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002244245A Expired - Fee Related CA2244245C (fr) 1996-02-01 1997-01-30 Composes de dihydrobenzofurane utilise comme agents anti-inflammatoires

Country Status (1)

Country Link
CA (1) CA2244245C (fr)

Also Published As

Publication number Publication date
CA2244245A1 (fr) 1997-08-07

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