CA2242354A1 - Pyrrolopyrimidines and processes for their preparation - Google Patents

Pyrrolopyrimidines and processes for their preparation

Info

Publication number
CA2242354A1
CA2242354A1 CA002242354A CA2242354A CA2242354A1 CA 2242354 A1 CA2242354 A1 CA 2242354A1 CA 002242354 A CA002242354 A CA 002242354A CA 2242354 A CA2242354 A CA 2242354A CA 2242354 A1 CA2242354 A1 CA 2242354A1
Authority
CA
Canada
Prior art keywords
ring
marked
bond
saturated
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002242354A
Other languages
French (fr)
Other versions
CA2242354C (en
Inventor
Peter Traxler
Jorg Frei
Guido Bold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/EP1997/000127 external-priority patent/WO1997027199A1/en
Publication of CA2242354A1 publication Critical patent/CA2242354A1/en
Application granted granted Critical
Publication of CA2242354C publication Critical patent/CA2242354C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

There are described compounds of formula (I) wherein R1 and R2 are as defined in the description, Q is heterocyclyl bonded via a ring nitrogen atom and having formula (IA) wherein R3 and R4 and m and n are as defined in the description, the ring marked A is a heterocyclyl having from 5 to 9 ring atoms and having at least one saturated bond, it being possible for a further ring hetero atom selected from O and S to be present in addition to the bonding nitrogen atom, the ring system marked B is a free or benzo-, thieno-, furo-, pyrrolo-or dihydropyrrolo-fused carbocyclic ring having from 5 to 9 carbon atoms that is fused to the ring A and may be unsaturated, partially saturated or fully saturated, and the bond marked by a parallel dotted line between the ring systems marked A and B is either a single bond or a double bond, and a salt thereof where at least one salt-forming group is present. The compounds are inhibitors of protein kinases and have, for example, antitumour activity.
CA002242354A 1996-01-23 1997-01-13 Pyrrolopyrimidines and processes for their preparation Expired - Fee Related CA2242354C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH17596 1996-01-23
CH175/96 1996-01-23
PCT/EP1997/000127 WO1997027199A1 (en) 1996-01-23 1997-01-13 Pyrrolopyrimidines and processes for their preparation

Publications (2)

Publication Number Publication Date
CA2242354A1 true CA2242354A1 (en) 1997-07-31
CA2242354C CA2242354C (en) 2006-07-25

Family

ID=36709440

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002242354A Expired - Fee Related CA2242354C (en) 1996-01-23 1997-01-13 Pyrrolopyrimidines and processes for their preparation

Country Status (1)

Country Link
CA (1) CA2242354C (en)

Also Published As

Publication number Publication date
CA2242354C (en) 2006-07-25

Similar Documents

Publication Publication Date Title
AU1441497A (en) Pyrrolopyrimidines and processes for their preparation
UA27748C2 (en) Derivatives of pyrimidine having activity of angiotensin II, a process for preparation thereof and pharmaceutical composition
TR199700844T1 (en) Pyrazolyl-Benzoil T�revleri.
AU626699B2 (en) Substituted quinazolinones as angiotensin ii antagonists
CA2017025A1 (en) Tumor necrosis factor binding protein ii, its purification and antibodies thereto
ATE269290T1 (en) BENZOYL DERIVATIVES
ES2113652T3 (en) RISPERIDONE PAMOATE.
ES2139094T3 (en) BRIDGED CATALYTIC COMPONENTS OF AMIDO-SILADIIL, METHOD OF MANUFACTURE AND USE.
ATE170865T1 (en) SOLID FIBER IN OLIGONUCLEOTIDE SYNTHESIS
DE68928174D1 (en) Process for the preparation of cephem derivatives
BR9712140A (en) Agents and processes to inhibit cytokine production, banknote adhesion and tnf - alpha production and use of a compound.
EP0296581A3 (en) Amino acid 1,2-diketo derivatives as renin inhibitors
FI894459A0 (en) Process for the preparation of novel quinolyloxazol-2-ones useful as inhibitors of protein kinase C
DE3855017D1 (en) Process for the preparation of condensed pyridine compounds
CA2242354A1 (en) Pyrrolopyrimidines and processes for their preparation
AU610473B2 (en) 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
ES2169053T3 (en) INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF CEPHALOSPORINS.
DK0832101T3 (en) Urethane-mediated, GST-specific molecular release systems
AU3138389A (en) Peptides with pharmaceutical activity
AU3617489A (en) A peptide with antihypertensive activity
ITTO930075A0 (en) PROCEDURE FOR THE CREATION OF BOXED STRUCTURAL PARTS FOR VEHICLE BODYWORK.
EP0370712A3 (en) Ethylamine derivatives and hypotensives containing the same
TW197946B (en)
IL89537A (en) Di- and tripeptides having inhibitory action on the enzymatic system, their preparation and pharmaceutical compositions containing them
DK0689543T3 (en) Process for Preparation of Condensed Carbapenem Derivatives

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130114