CA2238621A1 - Novel drug for relieving pain and promoting the removal of calculi in urolithiasis - Google Patents

Novel drug for relieving pain and promoting the removal of calculi in urolithiasis

Info

Publication number
CA2238621A1
CA2238621A1 CA002238621A CA2238621A CA2238621A1 CA 2238621 A1 CA2238621 A1 CA 2238621A1 CA 002238621 A CA002238621 A CA 002238621A CA 2238621 A CA2238621 A CA 2238621A CA 2238621 A1 CA2238621 A1 CA 2238621A1
Authority
CA
Canada
Prior art keywords
urolithiasis
calculi
promoting
removal
relieving pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002238621A
Other languages
French (fr)
Other versions
CA2238621C (en
Inventor
Masuo Akahane
Yoshitaka Tomiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/JP1996/003494 external-priority patent/WO1997019700A1/en
Publication of CA2238621A1 publication Critical patent/CA2238621A1/en
Application granted granted Critical
Publication of CA2238621C publication Critical patent/CA2238621C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to a novel drug for relieving pain and promoting the removal of calculi in urolithiasis which contains as the active ingredient a drug having the stimulating effects on both .beta.2- and .beta.3-adrenoceptors and exerting a potent relaxing effect on human ureteral smooth muscle.
CA002238621A 1995-11-30 1996-11-29 Novel drug for relieving pain and promoting the removal of calculi in urolithiasis Expired - Fee Related CA2238621C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP346599/1995 1995-11-30
JP34659995 1995-11-30
PCT/JP1996/003494 WO1997019700A1 (en) 1995-11-30 1996-11-29 Novel drug for relieving pain and promoting the removal of calculi in urolithiasis

Publications (2)

Publication Number Publication Date
CA2238621A1 true CA2238621A1 (en) 1997-06-05
CA2238621C CA2238621C (en) 2007-06-19

Family

ID=38282522

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002238621A Expired - Fee Related CA2238621C (en) 1995-11-30 1996-11-29 Novel drug for relieving pain and promoting the removal of calculi in urolithiasis

Country Status (1)

Country Link
CA (1) CA2238621C (en)

Also Published As

Publication number Publication date
CA2238621C (en) 2007-06-19

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20141201