CA2237571A1 - A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii - Google Patents

A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii

Info

Publication number
CA2237571A1
CA2237571A1 CA002237571A CA2237571A CA2237571A1 CA 2237571 A1 CA2237571 A1 CA 2237571A1 CA 002237571 A CA002237571 A CA 002237571A CA 2237571 A CA2237571 A CA 2237571A CA 2237571 A1 CA2237571 A1 CA 2237571A1
Authority
CA
Canada
Prior art keywords
glibenclamide
treatment
type
diabetes mellitus
metformin combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002237571A
Other languages
French (fr)
Other versions
CA2237571C (en
Inventor
Giulio Barelli
Massimo De Regis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abiogen Pharma SRL
Original Assignee
Abiogen Pharma S.R.L.
Giulio Barelli
Massimo De Regis
Abiogen Pharma S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT95MI002337A external-priority patent/IT1276130B1/en
Application filed by Abiogen Pharma S.R.L., Giulio Barelli, Massimo De Regis, Abiogen Pharma S.P.A. filed Critical Abiogen Pharma S.R.L.
Publication of CA2237571A1 publication Critical patent/CA2237571A1/en
Application granted granted Critical
Publication of CA2237571C publication Critical patent/CA2237571C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide

Abstract

A combination of glibenclamide and metformin such that, when administered in the form of pharmaceutical composition in the treatment of diabetes mellitus of type II, the ratio between the two active principles allows to obtain an optimum therapeutical effect at any time of the progression of the disease, avoiding to make use of the insulin therapy in the most severe cases.
CA002237571A 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii Expired - Fee Related CA2237571C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI95A002337 1995-11-14
IT95MI002337A IT1276130B1 (en) 1995-11-14 1995-11-14 GLIBENCLAMIDE-METFORMIN ASSOCIATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT AND THEIR USE IN THE TREATMENT OF TYPE DIABETES MELLITUS
PCT/EP1996/004860 WO1997017975A1 (en) 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii

Publications (2)

Publication Number Publication Date
CA2237571A1 true CA2237571A1 (en) 1997-05-22
CA2237571C CA2237571C (en) 2007-01-23

Family

ID=37684470

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002237571A Expired - Fee Related CA2237571C (en) 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii

Country Status (1)

Country Link
CA (1) CA2237571C (en)

Also Published As

Publication number Publication date
CA2237571C (en) 2007-01-23

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20161107