CA2237000A1 - Stable packaging cell line producing pseudotyped retroviruses - Google Patents

Stable packaging cell line producing pseudotyped retroviruses Download PDF

Info

Publication number
CA2237000A1
CA2237000A1 CA 2237000 CA2237000A CA2237000A1 CA 2237000 A1 CA2237000 A1 CA 2237000A1 CA 2237000 CA2237000 CA 2237000 CA 2237000 A CA2237000 A CA 2237000A CA 2237000 A1 CA2237000 A1 CA 2237000A1
Authority
CA
Canada
Prior art keywords
retroviral
gagpol
cell line
cells
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2237000
Other languages
English (en)
French (fr)
Inventor
Daniel S. Ory
Michel Sadelain
Richard C. Mulligan
Jean E. Schaffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whitehead Institute for Biomedical Research
Washington University in St Louis WUSTL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2237000A1 publication Critical patent/CA2237000A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13051—Methods of production or purification of viral material
    • C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA 2237000 1995-11-08 1996-11-07 Stable packaging cell line producing pseudotyped retroviruses Abandoned CA2237000A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US55515595A 1995-11-08 1995-11-08
US08/555,155 1995-11-08
US65105096A 1996-05-21 1996-05-21
US08/651,050 1996-05-21

Publications (1)

Publication Number Publication Date
CA2237000A1 true CA2237000A1 (en) 1997-05-15

Family

ID=27070812

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2237000 Abandoned CA2237000A1 (en) 1995-11-08 1996-11-07 Stable packaging cell line producing pseudotyped retroviruses

Country Status (4)

Country Link
EP (1) EP0859856A2 (de)
JP (1) JP2000500013A (de)
CA (1) CA2237000A1 (de)
WO (1) WO1997017457A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL132596A0 (en) 1997-06-04 2001-03-19 Oxford Biomedica Ltd Vector
AU1334999A (en) * 1997-10-20 1999-05-10 Universita Degli Studi Di Padova A packaging cell line producing siv-pseudotyped mlv
PT1076715E (pt) 1998-05-13 2007-10-26 Genetix Pharmaceuticals Inc Células empacotadoras lentivirais
GB0009760D0 (en) 2000-04-19 2000-06-07 Oxford Biomedica Ltd Method
GB0024550D0 (de) 2000-10-06 2000-11-22 Oxford Biomedica Ltd
CA2344208A1 (en) 2001-04-30 2002-10-30 Oxford Biomedica (Uk) Limited Method
AUPR518501A0 (en) 2001-05-22 2001-06-14 Unisearch Limited Yin yang-1
EP1504108B1 (de) 2002-02-01 2013-04-17 Oxford Biomedica (UK) Limited Lentiviraler Vektor
WO2006120473A2 (en) 2005-05-13 2006-11-16 Oxford Biomedica (Uk) Limited Mhc class i and ii peptide antigens derived from tumour antigen 5t4
EP2389443B1 (de) 2009-01-23 2018-11-14 Roger Williams Hospital Retrovirale vektoren kodierend für multiple stark homologe nichtvirale polypeptide und ihre verwendung
CN103328038A (zh) 2010-12-01 2013-09-25 史拜诺莫度雷森公司 向神经解剖结构直接递送药剂
GB201318804D0 (en) 2013-10-24 2013-12-11 Adaptimmune Ltd Vectors for transgene expression
DE102020106710A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512421A (en) * 1991-02-19 1996-04-30 The Regents Of The University Of California Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors
EP0769968B1 (de) * 1994-08-17 2005-01-26 Genetic Therapy, Inc. Retrovirale vektoren, die von gegen lyse durch menschliches serum resistenten produktionszellinien produziert werden
US5750396A (en) * 1995-05-08 1998-05-12 St. Judes Children's Research Hospital Stable virus packaging cell lines

Also Published As

Publication number Publication date
JP2000500013A (ja) 2000-01-11
WO1997017457A2 (en) 1997-05-15
WO1997017457A3 (en) 1997-09-12
EP0859856A2 (de) 1998-08-26

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead