CA2233560C - Inhibiteurs de metalloprotineases matricielles a base de sulfamide - Google Patents
Inhibiteurs de metalloprotineases matricielles a base de sulfamide Download PDFInfo
- Publication number
- CA2233560C CA2233560C CA002233560A CA2233560A CA2233560C CA 2233560 C CA2233560 C CA 2233560C CA 002233560 A CA002233560 A CA 002233560A CA 2233560 A CA2233560 A CA 2233560A CA 2233560 C CA2233560 C CA 2233560C
- Authority
- CA
- Canada
- Prior art keywords
- phenyl
- compound
- benzenesulfonylamino
- piperidin
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention a trait à des composés de sulfamide, inhibiteurs de métalloprotinéases matricielles, notamment la stromélysine-1 et la gélatinase A (gélatinase de 72 kD). Elle concerne également des méthodes faisant appel à ces composés pour le traitement de la sclérose en plaques, de la rupture de la plaque athéroscléreuse, de l'anévrisme aortique, de l'insuffisance cardiaque, de la resténose, de la parodontopathie, de l'ulcération cornéenne, des brûlures, des ulcères du décubitus, d'ulcères chroniques ou de lésions, de métastases cancéreuses, de l'angiogénèse tumorale, de l'arthrite ou d'autres affections auto-immunes ou inflammatoires liées à une invasion leucocytaire des tissus.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US737295P | 1995-11-17 | 1995-11-17 | |
| US60/007,372 | 1995-11-17 | ||
| PCT/US1996/016761 WO1997019068A1 (fr) | 1995-11-17 | 1996-10-18 | Inhibiteurs de metalloprotineases matricielles a base de sulfamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2233560A1 CA2233560A1 (fr) | 1997-05-29 |
| CA2233560C true CA2233560C (fr) | 2005-12-20 |
Family
ID=35645828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002233560A Expired - Fee Related CA2233560C (fr) | 1995-11-17 | 1996-10-18 | Inhibiteurs de metalloprotineases matricielles a base de sulfamide |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2233560C (fr) |
-
1996
- 1996-10-18 CA CA002233560A patent/CA2233560C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2233560A1 (fr) | 1997-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |