CA2233173C - Ligands de transporteurs de la dopamine et de la serotonine et agents d'imagerie - Google Patents

Ligands de transporteurs de la dopamine et de la serotonine et agents d'imagerie Download PDF

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Publication number
CA2233173C
CA2233173C CA002233173A CA2233173A CA2233173C CA 2233173 C CA2233173 C CA 2233173C CA 002233173 A CA002233173 A CA 002233173A CA 2233173 A CA2233173 A CA 2233173A CA 2233173 C CA2233173 C CA 2233173C
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compound
coa
group
compounds
cor
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Expired - Fee Related
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CA002233173A
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English (en)
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CA2233173A1 (fr
Inventor
Hank F. Kung
Sanath Meegalla
Mei-Ping Kung
Karl Plossl
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University of Pennsylvania Penn
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University of Pennsylvania Penn
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Priority claimed from US08/649,782 external-priority patent/US6241963B1/en
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of CA2233173A1 publication Critical patent/CA2233173A1/fr
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Publication of CA2233173C publication Critical patent/CA2233173C/fr
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Abstract

La présente invention concerne une série de nouveaux dérivés à base de tropane complexés avec du technétium ou du rhénium, qui sont spécifiques des récepteurs du système nerveux central, notamment des récepteurs de la dopamine et de la sérotonine. Ces composés sont utiles, entre autres, comme agents d'imagerie pour les récepteurs du système nerveux central. L'invention décrit des procédés d'utilisation de ces nouveaux composés comme agents d'imagerie, ainsi que des intermédiaires et des procédés pour fabriquer ces nouveaux composés.
CA002233173A 1995-10-19 1996-10-21 Ligands de transporteurs de la dopamine et de la serotonine et agents d'imagerie Expired - Fee Related CA2233173C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US54532795A 1995-10-19 1995-10-19
US08/545,327 1995-10-19
US08/649,782 US6241963B1 (en) 1995-10-19 1996-05-17 Dopamine and serotonin transporter ligands and imaging agents
US08/649,782 1996-05-17
PCT/US1996/016908 WO1997014445A1 (fr) 1995-10-19 1996-10-21 Ligands de transporteurs de la dopamine et de la serotonine et agents d'imagerie

Publications (2)

Publication Number Publication Date
CA2233173A1 CA2233173A1 (fr) 1997-04-24
CA2233173C true CA2233173C (fr) 2006-04-04

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CA002233173A Expired - Fee Related CA2233173C (fr) 1995-10-19 1996-10-21 Ligands de transporteurs de la dopamine et de la serotonine et agents d'imagerie

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CA2233173A1 (fr) 1997-04-24

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