CA2225741A1 - Ionophore antibiotic formulations - Google Patents
Ionophore antibiotic formulationsInfo
- Publication number
- CA2225741A1 CA2225741A1 CA002225741A CA2225741A CA2225741A1 CA 2225741 A1 CA2225741 A1 CA 2225741A1 CA 002225741 A CA002225741 A CA 002225741A CA 2225741 A CA2225741 A CA 2225741A CA 2225741 A1 CA2225741 A1 CA 2225741A1
- Authority
- CA
- Canada
- Prior art keywords
- optionally
- agent
- ionophore antibiotic
- iii
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 5
- 239000002555 ionophore Substances 0.000 title abstract 5
- 230000000236 ionophoric effect Effects 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- 239000007798 antifreeze agent Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000010790 dilution Methods 0.000 abstract 2
- 239000012895 dilution Substances 0.000 abstract 2
- 229920001285 xanthan gum Polymers 0.000 abstract 2
- 229940082509 xanthan gum Drugs 0.000 abstract 2
- 235000010493 xanthan gum Nutrition 0.000 abstract 2
- 239000000230 xanthan gum Substances 0.000 abstract 2
- 229930191564 Monensin Natural products 0.000 abstract 1
- GAOZTHIDHYLHMS-UHFFFAOYSA-N Monensin A Natural products O1C(CC)(C2C(CC(O2)C2C(CC(C)C(O)(CO)O2)C)C)CCC1C(O1)(C)CCC21CC(O)C(C)C(C(C)C(OC)C(C)C(O)=O)O2 GAOZTHIDHYLHMS-UHFFFAOYSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000002518 antifoaming agent Substances 0.000 abstract 1
- -1 bloat Chemical compound 0.000 abstract 1
- 230000003139 buffering effect Effects 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 229960005358 monensin Drugs 0.000 abstract 1
- GAOZTHIDHYLHMS-KEOBGNEYSA-N monensin A Chemical compound C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C(O)=O)O2 GAOZTHIDHYLHMS-KEOBGNEYSA-N 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 229940083037 simethicone Drugs 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
- 239000004546 suspension concentrate Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
An aqueous base suspension concentrate or use of ionophore antibiotic(s) capable of aqueous dilution (if desired) and capable (with or without such aqueous dilution) of being orally administered to an animal (e.g. by drenching) to prevent or treat conditions treatable by an ionophore antibiotic such as monensin (e.g. bloat, coccidiosis, et al), said concentrate comprising: (I) at least one ionophore antibiotic in (II) an aqueous system containing: (i) optionally a wetting and/or surfactant agent, (ii) optionally, an antifreeze agent or agents in which the ionophore antibiotic or antibiotics is or are no more than sparingly soluble (preferably organic, e.g. a glycol), (iii) a suspension agent (optionally Xanthan gum), (iv) optionally an antifoam agent or system (optionally a Simethicone and particulate carrier system), (v) optionally a preservative, (vi) optionally a de-battering agent, (vii) optionally a pH buffering system, and (viii) water, wherein (iii) is Xanthan gum or at least two of (i), (ii) and (iii) are present in (II).
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ272574A NZ272574A (en) | 1995-07-14 | 1995-07-14 | Aqueous base suspension concentrate containing at least one ionophore antibiotic and wetting agent and/or a surfactant and xanthan gum optionally with a suspension agent, an antifreeze agent and an antifoaming agent; drench for veterinary treatment |
| NZ272574 | 1995-07-14 | ||
| NZ272940 | 1995-09-06 | ||
| PCT/NZ1996/000068 WO1997003650A1 (en) | 1995-07-14 | 1996-07-04 | Ionophore antibiotic formulations |
| NZ27294096 | 1996-09-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2225741A1 true CA2225741A1 (en) | 1997-02-06 |
| CA2225741C CA2225741C (en) | 2006-10-03 |
Family
ID=26651484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225741A Expired - Fee Related CA2225741C (en) | 1995-07-14 | 1996-07-04 | Ionophore antibiotic formulations |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2225741C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10117849B2 (en) * | 2015-04-28 | 2018-11-06 | ELANCO US, Inc. | Monensin water dispersible granules by wet granulation |
-
1996
- 1996-07-04 CA CA002225741A patent/CA2225741C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10117849B2 (en) * | 2015-04-28 | 2018-11-06 | ELANCO US, Inc. | Monensin water dispersible granules by wet granulation |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2225741C (en) | 2006-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |