CA2223878A1 - Inhibitors of phospholipase a2 - Google Patents
Inhibitors of phospholipase a2 Download PDFInfo
- Publication number
- CA2223878A1 CA2223878A1 CA002223878A CA2223878A CA2223878A1 CA 2223878 A1 CA2223878 A1 CA 2223878A1 CA 002223878 A CA002223878 A CA 002223878A CA 2223878 A CA2223878 A CA 2223878A CA 2223878 A1 CA2223878 A1 CA 2223878A1
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- Prior art keywords
- uteroglobin
- cells
- tumor
- effector
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| US08/486,203 | 1995-06-07 | ||
| US08/486,203 US5830640A (en) | 1995-03-07 | 1995-06-07 | Determining invasiveness of prostatic adenocarcinoma |
| US08/658,796 US5935860A (en) | 1995-03-07 | 1996-06-05 | Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia |
| US08/658,796 | 1996-06-05 |
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|---|---|
| CA2223878A1 true CA2223878A1 (en) | 1996-12-19 |
Family
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|---|---|---|---|
| CA002223878A Abandoned CA2223878A1 (en) | 1995-06-07 | 1996-06-06 | Inhibitors of phospholipase a2 |
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|---|---|
| US (5) | US5935860A (enExample) |
| EP (1) | EP0840729A4 (enExample) |
| JP (2) | JPH11507644A (enExample) |
| AU (1) | AU6174696A (enExample) |
| CA (1) | CA2223878A1 (enExample) |
| IL (1) | IL122266A (enExample) |
| WO (1) | WO1996040657A1 (enExample) |
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| US6358915B1 (en) * | 1995-03-07 | 2002-03-19 | George Washington University | Methods for inhibiting metastasis |
| US5935860A (en) * | 1995-03-07 | 1999-08-10 | The George Washington University | Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia |
| US20060281681A1 (en) | 1997-05-28 | 2006-12-14 | Pilon Aprile L | Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease |
| US6255281B1 (en) * | 1997-05-28 | 2001-07-03 | Claragen, Inc. And U.S. Government | Use of recombinant human uteroglobin in treatment of inflammatory and fibrotic conditions |
| US20020160948A1 (en) * | 1998-07-21 | 2002-10-31 | Aprile Pilon | Recombinant human uteroglobin in treatment of inflammatory and fibrotic conditions |
| CA2406383A1 (en) * | 2000-04-13 | 2001-10-25 | Mayo Foundation For Medical Education And Research | A.beta.42 lowering agents |
| WO2001080872A1 (en) * | 2000-04-21 | 2001-11-01 | George Washington University | Method of binding integrin for treatment of cancer |
| EP1300159B1 (en) * | 2000-06-29 | 2007-10-10 | Anthera Pharmaceuticals, Inc. | Remedies for cancer |
| US20030114410A1 (en) * | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| WO2003048341A2 (en) * | 2001-12-03 | 2003-06-12 | Uab Research Foundation | Cap-gly domain structure and uses thereof |
| AUPS282602A0 (en) * | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| US20050259483A1 (en) * | 2002-09-30 | 2005-11-24 | Oncotherapy Science, Inc. | Genes and polypeptides relating to prostate cancers |
| TW200413539A (en) * | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Genes and polypeptides relating to prostate cancers |
| WO2004046329A2 (en) * | 2002-11-14 | 2004-06-03 | Pintex Pharmaceuticals, Inc. | Levels of pin1 in normal and cancerous tissue |
| WO2004071431A2 (en) * | 2003-02-05 | 2004-08-26 | Myriad Genetics, Inc. | Method and composition for treating neurodegenerative disorders |
| WO2005065069A2 (en) * | 2003-07-11 | 2005-07-21 | Myriad Genetics, Inc. | Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease |
| US7070816B2 (en) * | 2003-12-05 | 2006-07-04 | New Chapter, Inc. | Methods for treating prostatic intraepithelial neoplasia with herbal compositions |
| WO2006001877A2 (en) * | 2004-04-13 | 2006-01-05 | Myriad Genetics, Inc. | Combination treatment for neurodegenerative disorders comprising r-flurbiprofen |
| WO2005108683A1 (en) * | 2004-04-29 | 2005-11-17 | Keystone Retaining Wall Systems, Inc. | Veneers for walls, retaining walls and the like |
| WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| BRPI0514303A (pt) * | 2004-08-11 | 2008-06-10 | Myriad Genetics Inc | composição farmacêutica e método para tratar distúrbios neurodegenerativos |
| US20070225242A1 (en) * | 2005-06-21 | 2007-09-27 | The Board Of Trustees Of The Leland Stanford Junior University | Method and composition for treating and preventing tumor metastasis in vivo |
| EP1909777A2 (en) * | 2005-07-22 | 2008-04-16 | Myriad Genetics, Inc. | High drug load formulations and dosage forms |
| EP2046119A2 (en) * | 2006-07-07 | 2009-04-15 | Myriad Genetics, Inc. | Treatment of psychiatric disorders |
| IL184627A0 (en) | 2007-07-15 | 2008-12-29 | Technion Res & Dev Foundation | Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue |
| CN110372795A (zh) | 2007-08-02 | 2019-10-25 | 吉利德生物制剂公司 | Lox和loxl2抑制剂及其应用 |
| CN102292099A (zh) | 2008-05-13 | 2011-12-21 | 科拉森斯公司 | 在鼻炎治疗中使用的重组人cc10及其组合物 |
| WO2010080769A2 (en) | 2009-01-06 | 2010-07-15 | Arresto Biosciences, Inc. | Chemotherapeutic methods and compositions |
| RU2012110585A (ru) | 2009-08-21 | 2013-09-27 | Джилид Байолоджикс, Инк. | Каталичические домены лизилоксидазы и loxl2 |
| EP2488205B1 (en) | 2009-10-15 | 2016-09-21 | Clarassance, Inc. | Recombinant human cc10 protein for treatment of influenza |
| US9168285B2 (en) | 2009-10-15 | 2015-10-27 | Therabron Therapeutics, Inc. | Recombinant human CC10 protein for treatment of influenza and ebola |
| RU2015108348A (ru) | 2010-02-04 | 2015-07-20 | Джилид Байолоджикс, Инк. | Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения |
| EP2407554A1 (en) | 2010-07-14 | 2012-01-18 | Fundacio Institut de Recerca de l'Hospital Universitari Vall d'Hebron | Methods and kits for the diagnosis of prostate cancer |
| EP2407555A1 (en) | 2010-07-14 | 2012-01-18 | Fundació Institut de Recerca Hospital Universitari Vall d'Hebron, Fundació Privada | Methods and kits for the diagnosis of prostate cancer |
| ES2638089T3 (es) * | 2011-02-24 | 2017-10-18 | Ventana Medical Systems, Inc. | Presencia de reordenamientos del gen ERG y sobreexpresión de proteínas en NIP de bajo grado (NIP-BG) en biopsias de próstata |
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| US4489166A (en) * | 1982-05-27 | 1984-12-18 | Research Corporation | Monitoring of human endometrial function by radioimmunoassay of PEP |
| US5266562A (en) * | 1987-11-19 | 1993-11-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Anti-inflammatory agents |
| US5662896A (en) * | 1988-03-21 | 1997-09-02 | Chiron Viagene, Inc. | Compositions and methods for cancer immunotherapy |
| US5219752A (en) * | 1988-05-25 | 1993-06-15 | Teijin, Limited | Process for continuously culturing adherent animal cells |
| US5086164A (en) * | 1989-01-10 | 1992-02-04 | Repligen Corporation | Novel methods and compositions for treatment of angiogenic diseases |
| US5132315A (en) * | 1989-05-19 | 1992-07-21 | The United States Of America As Represented By The Department Of Health And Human Services | Therapeutic application of an anti-invasive compound |
| US5359078A (en) * | 1989-05-19 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor compounds |
| DE3937607A1 (de) * | 1989-11-11 | 1991-05-16 | Boehringer Ingelheim Int | Verwendung eines antikoagulanz zur behandlung von tumorerkrankungen |
| CA2094203A1 (en) * | 1993-04-16 | 1994-10-17 | Derek A. Willoughby | Inhibition of angiogenesis |
| US5935860A (en) * | 1995-03-07 | 1999-08-10 | The George Washington University | Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia |
| US5696092A (en) * | 1995-03-07 | 1997-12-09 | George Washington University | Methods and compositions for inhibiting metastasis of epithelial cell-derived cancers |
-
1996
- 1996-06-05 US US08/658,796 patent/US5935860A/en not_active Expired - Lifetime
- 1996-06-06 JP JP9502246A patent/JPH11507644A/ja not_active Ceased
- 1996-06-06 AU AU61746/96A patent/AU6174696A/en not_active Abandoned
- 1996-06-06 WO PCT/US1996/010221 patent/WO1996040657A1/en not_active Ceased
- 1996-06-06 EP EP96919395A patent/EP0840729A4/en not_active Withdrawn
- 1996-06-06 CA CA002223878A patent/CA2223878A1/en not_active Abandoned
- 1996-06-06 IL IL12226696A patent/IL122266A/xx not_active IP Right Cessation
-
1997
- 1997-11-07 US US08/966,196 patent/US6054320A/en not_active Expired - Lifetime
-
2000
- 2000-02-25 US US09/512,385 patent/US6316416B1/en not_active Expired - Fee Related
- 2000-04-21 US US09/556,467 patent/US6395715B1/en not_active Expired - Fee Related
- 2000-04-21 US US09/556,468 patent/US6335321B1/en not_active Expired - Fee Related
-
2007
- 2007-12-17 JP JP2007324925A patent/JP2008156353A/ja active Pending
Also Published As
| Publication number | Publication date |
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| US6335321B1 (en) | 2002-01-01 |
| JPH11507644A (ja) | 1999-07-06 |
| US6395715B1 (en) | 2002-05-28 |
| AU6174696A (en) | 1996-12-30 |
| EP0840729A4 (en) | 2000-11-02 |
| US6054320A (en) | 2000-04-25 |
| JP2008156353A (ja) | 2008-07-10 |
| WO1996040657A1 (en) | 1996-12-19 |
| IL122266A (en) | 2005-11-20 |
| US6316416B1 (en) | 2001-11-13 |
| US5935860A (en) | 1999-08-10 |
| IL122266A0 (en) | 1998-04-05 |
| EP0840729A1 (en) | 1998-05-13 |
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