CA2219082A1 - Utilisation de composes de dihydrotestosterone pour traiter une dysfonction sexuelle chez l'homme - Google Patents

Utilisation de composes de dihydrotestosterone pour traiter une dysfonction sexuelle chez l'homme Download PDF

Info

Publication number
CA2219082A1
CA2219082A1 CA 2219082 CA2219082A CA2219082A1 CA 2219082 A1 CA2219082 A1 CA 2219082A1 CA 2219082 CA2219082 CA 2219082 CA 2219082 A CA2219082 A CA 2219082A CA 2219082 A1 CA2219082 A1 CA 2219082A1
Authority
CA
Canada
Prior art keywords
dihydrotestosterone
dht
sexual dysfunction
subject
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2219082
Other languages
English (en)
Inventor
Christo S. Mantzoros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2219082A1 publication Critical patent/CA2219082A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention décrit une méthode de traitement d'une dysfonction sexuelle chez un patient, consistant à élever les taux de dihydrotestostérone (DHT) chez un patient pour traiter efficacement ladite dysfonction sexuelle. Les méthodes de l'invention peuvent être utilisées dans le cadre d'un traitement prophylactique et/ou thérapeutique des dysfonctions sexuelles.
CA 2219082 1995-05-15 1996-05-01 Utilisation de composes de dihydrotestosterone pour traiter une dysfonction sexuelle chez l'homme Abandoned CA2219082A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44072695A 1995-05-15 1995-05-15
US08/440,726 1995-05-15
US48747195A 1995-06-07 1995-06-07
US08/487,471 1995-06-07

Publications (1)

Publication Number Publication Date
CA2219082A1 true CA2219082A1 (fr) 1996-11-21

Family

ID=27032530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2219082 Abandoned CA2219082A1 (fr) 1995-05-15 1996-05-01 Utilisation de composes de dihydrotestosterone pour traiter une dysfonction sexuelle chez l'homme

Country Status (4)

Country Link
EP (1) EP0827405A2 (fr)
AU (1) AU5671496A (fr)
CA (1) CA2219082A1 (fr)
WO (1) WO1996036339A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
GB0409498D0 (en) * 2004-04-28 2004-06-02 Hunter Fleming Ltd Transdermal steroid formulation
AU2005239962B2 (en) 2004-05-11 2011-07-07 Eb Ip Lybrido B.V. Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction
EP1790343A1 (fr) 2005-11-11 2007-05-30 Emotional Brain B.V. Compositions pharmaceutiques et leur utilisation pour le traitement des dysfonctions sexuelles chez la femme
EP1925307A1 (fr) 2006-11-03 2008-05-28 Emotional Brain B.V. Utilisation de 3-alpha-androstanediol pour le traitement des dysfonctions sexuelles

Also Published As

Publication number Publication date
WO1996036339A3 (fr) 1997-02-13
EP0827405A2 (fr) 1998-03-11
WO1996036339A2 (fr) 1996-11-21
AU5671496A (en) 1996-11-29

Similar Documents

Publication Publication Date Title
McGINNIS et al. Evidence for a role of testosterone-androgen receptor interactions in mediating masculine sexual behavior in male rats
Martini The 5α-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications
Chahal et al. The endocrine system and ageing
Casper et al. Aromatase inhibitors for ovulation induction
Simon et al. Differential effects of estrogen-androgen and estrogen-only therapy on vasomotor symptoms, gonadotropin secretion, and endogenous androgen bioavailability in postmenopausal women
Gonzalez et al. Role of 17beta-estradiol and/or progesterone on insulin sensitivity in the rat: implications during pregnancy
Wallach et al. Polycystic ovarian disease: current concepts of pathophysiology and therapy
Luttge Effects of anti-estrogens on testosterone stimulated male sexual behavior and peripheral target tissues in the castrate male rat
D'occhio et al. Effects of androgenic and oestrogenic hormones on mating behaviour in rams castrated before or after puberty
Luttge et al. Stimulation of male and female sexual behavior in gonadectomized rats with estrogen and androgen therapy and its inhibition with concurrent anti-hormone therapy
Hillier et al. Hormonal regulation of preovulatory follicle maturation in the rat
Yahr et al. Aromatization and androgen stimulation of sexual behavior in male and female rats
Rissman et al. Role of androgens in the regulation of sexual behavior in the female musk shrew
Baum et al. Normal differentiation of masculine sexual behavior in male ferrets despite neonatal inhibition of brain aromatase or 5-alpha-reductase activity
Alonso et al. Steroid influences on pineal melatonin production
Carmina et al. Physiological estrogen replacement may enhance the effectiveness of the gonadotropin-releasing hormone agonist in the treatment of hirsutism
Guido et al. Ethinylestradio-Chlormadinone Acetate Combination for the Treatment of Hirsutism and Hormonal Alterations of Normal-Weight Women With Polycystic Ovary Syndrome: Evaluation of the Metabolic Impact
Buvat et al. Hormones, metabolism, aging and men’s health
Hoskins et al. TTHE INHIBITION OF COMB GROWTH IN COCKERELS AND CAPONS BY ESTRONEW
Migeon et al. Adrenal cortex: hypo-and hyperfunction
CA2219082A1 (fr) Utilisation de composes de dihydrotestosterone pour traiter une dysfonction sexuelle chez l'homme
Zumpe et al. Behavioral responses to Depo-Provera, Fadrozole, and estradiol in castrated, testosterone-treated cynomolgus monkeys (Macaca fascicularis): the involvement of progestin receptors
Phoenix Sexual behavior of castrated male rhesus monkeys treated with 19-hydroxytestosterone
Lephart et al. Altered brain and pituitary androgen metabolism by prenatal, perinatal or pre-and postnatal finasteride, flutamide or dihydrotestosterone treatment in juvenile male rats
Clemens et al. Testosterone acts as a prohormone to stimulate male copulatory behavior in male deer mice (Peromyscus maniculatus bairdi).

Legal Events

Date Code Title Description
FZDE Dead