CA2217551C - Photoactivated hypericin and the use thereof - Google Patents

Photoactivated hypericin and the use thereof Download PDF

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Publication number
CA2217551C
CA2217551C CA002217551A CA2217551A CA2217551C CA 2217551 C CA2217551 C CA 2217551C CA 002217551 A CA002217551 A CA 002217551A CA 2217551 A CA2217551 A CA 2217551A CA 2217551 C CA2217551 C CA 2217551C
Authority
CA
Canada
Prior art keywords
hypericin
leukocytes
derivative
tissue
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002217551A
Other languages
English (en)
French (fr)
Other versions
CA2217551A1 (en
Inventor
Floyd Eliot Fox
Alain H. Rook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania
Original Assignee
University of Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania filed Critical University of Pennsylvania
Publication of CA2217551A1 publication Critical patent/CA2217551A1/en
Application granted granted Critical
Publication of CA2217551C publication Critical patent/CA2217551C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002217551A 1997-07-03 1997-10-07 Photoactivated hypericin and the use thereof Expired - Fee Related CA2217551C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/887,546 1997-07-03
US08/887,546 US6001882A (en) 1997-07-03 1997-07-03 Photoactivated hypericin and the use thereof

Publications (2)

Publication Number Publication Date
CA2217551A1 CA2217551A1 (en) 1999-01-03
CA2217551C true CA2217551C (en) 2008-08-12

Family

ID=25391387

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002217551A Expired - Fee Related CA2217551C (en) 1997-07-03 1997-10-07 Photoactivated hypericin and the use thereof

Country Status (3)

Country Link
US (1) US6001882A (enExample)
JP (1) JPH1135456A (enExample)
CA (1) CA2217551C (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399298B1 (en) * 1998-06-30 2002-06-04 Sloan-Kettering Institute For Cancer Research Ku70—related methods
US6524330B1 (en) 2000-10-27 2003-02-25 Bahram Khoobehi Method of ocular treatment
US6561808B2 (en) * 2001-09-27 2003-05-13 Ceramoptec Industries, Inc. Method and tools for oral hygiene
US7235392B2 (en) * 2001-12-07 2007-06-26 The Ohio State University Research Foundation Apoptotic EBV-transformed lymphocytes, a therapeutic agent for post-transplant lymphoproliferative disorder
US20040038373A1 (en) * 2001-12-07 2004-02-26 Platz Matthew S. Apoptotic EBV-transformed lymphocytes, a therapeutic agent for post-transplant lymphoproliferative disorder
US20040259053A1 (en) * 2003-06-18 2004-12-23 Bekov George I. Method and apparatus for laser-assisted dental scaling
WO2009066294A1 (en) * 2007-11-20 2009-05-28 Hy Biopharma Inc. Device and method for photodynamic therapy
US8715920B2 (en) 2010-07-27 2014-05-06 Biovec Transfusion, Llc Composition for preserving platelets during photosensitization
EP2477957A4 (en) * 2009-09-15 2013-07-03 Hy Biopharma Inc PROCESS FOR PREPARING HYPERICIN
EP2932973B1 (en) 2010-05-04 2020-04-01 Soligenix, Inc. Formulations for use in the treatment of skin conditions
IL310029A (en) * 2021-07-08 2024-03-01 Soligenix Inc Dermatological preparations and methods for treating CUTANEOUS T-CELL LYMPHOMA
CN118766988A (zh) * 2024-08-23 2024-10-15 西南医科大学 一种天然植物细胞外囊泡光敏剂及其制备方法和在治疗炎症性皮肤病中的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4898891A (en) * 1987-08-07 1990-02-06 Yeda Research And Development Company Ltd. Antiviral compositions
IL92315A (en) * 1989-11-15 1996-12-05 Yeda Res & Dev Preparation of Hypericin from Amodin Enron
US5514714A (en) * 1990-08-23 1996-05-07 New York University Methods and polycyclic aromatic compound containing compositions for treating T-cell-mediated diseases
US5316768A (en) * 1990-12-28 1994-05-31 Murdock International Corporation Pharmaceutical compositions having antiviral activity against human cytomegalovirus
AU3474593A (en) * 1992-01-16 1993-08-03 New York University Hypericin treatment of vaccine agents for improved immunogenicity

Also Published As

Publication number Publication date
US6001882A (en) 1999-12-14
JPH1135456A (ja) 1999-02-09
CA2217551A1 (en) 1999-01-03

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Effective date: 20131009