CA2216870A1 - Compositions and methods for regulating hair growth - Google Patents

Compositions and methods for regulating hair growth

Info

Publication number
CA2216870A1
CA2216870A1 CA002216870A CA2216870A CA2216870A1 CA 2216870 A1 CA2216870 A1 CA 2216870A1 CA 002216870 A CA002216870 A CA 002216870A CA 2216870 A CA2216870 A CA 2216870A CA 2216870 A1 CA2216870 A1 CA 2216870A1
Authority
CA
Canada
Prior art keywords
hair
growth
hair growth
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002216870A
Other languages
French (fr)
Other versions
CA2216870C (en
Inventor
Tung-Tien Sun
Da-Wen Yu
Robert M. Lavker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
University of Pennsylvania Penn
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2216870A1 publication Critical patent/CA2216870A1/en
Application granted granted Critical
Publication of CA2216870C publication Critical patent/CA2216870C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A method of modulating hair growth by contacting selected cells with a selected growth-modulating molecule is provided. A method for hair reconstitution or transplantation by expanding selected cells in vitro and combining them with other cells that regulate hair growth are also provided.
Compositions containing a growth-modulating molecule which is synthesized by follicular cells and which undergoes hair-cycle-dependent concentration changes in hair follicles are also provided.
CA002216870A 1995-04-20 1996-04-19 Compositions and methods for regulating hair growth Expired - Lifetime CA2216870C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42578695A 1995-04-20 1995-04-20
US08/425,786 1995-04-20
PCT/US1996/005492 WO1996032961A1 (en) 1995-04-20 1996-04-19 Compositions and methods for regulating hair growth

Publications (2)

Publication Number Publication Date
CA2216870A1 true CA2216870A1 (en) 1996-10-24
CA2216870C CA2216870C (en) 2002-11-19

Family

ID=23688038

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002216870A Expired - Lifetime CA2216870C (en) 1995-04-20 1996-04-19 Compositions and methods for regulating hair growth

Country Status (5)

Country Link
EP (1) EP0821592A4 (en)
JP (1) JPH11504016A (en)
CA (1) CA2216870C (en)
MX (1) MX9708045A (en)
WO (1) WO1996032961A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1005445C2 (en) * 1997-03-05 1998-09-21 Gho St Holding B V Method of multiplying hair.
GB2493540A (en) * 2011-08-10 2013-02-13 Follicum Ab Agents for stimulating hair growth in mammals

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596812A (en) * 1976-05-24 1986-06-24 The Upjohn Company Methods and solutions for treating male pattern alopecia
US5053403A (en) * 1984-05-11 1991-10-01 Norman Orentreich Methods for treatment of male-pattern baldness
US5352442A (en) * 1985-07-18 1994-10-04 Proctor Peter H Topical tempo
GB8604360D0 (en) * 1986-02-21 1986-03-26 Univ Dundee Stimulation of hair growth
US5112608A (en) * 1987-03-13 1992-05-12 Incyte Pharmaceuticals Use of protease nexin-I to mediate wound healing
US5026691A (en) * 1987-03-30 1991-06-25 The Upjohn Company Combination of minoxidil and an antiinflammatory agent for treating patterned alopecia
DE3738620A1 (en) * 1987-11-13 1989-05-24 Luderschmidt Christoph USE OF ETHISTERONE FOR TOPICAL TREATMENT OF ACNE OR ANDROGENETIC ALOPECIA
US5556783A (en) * 1991-03-27 1996-09-17 Trustees Of Univ. Of Penna Methods of culturing and modulating the growth of hair follicular stem cells

Also Published As

Publication number Publication date
JPH11504016A (en) 1999-04-06
EP0821592A1 (en) 1998-02-04
EP0821592A4 (en) 2000-03-01
CA2216870C (en) 2002-11-19
MX9708045A (en) 1998-03-31
WO1996032961A1 (en) 1996-10-24

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20160419