CA2213842A1 - Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence - Google Patents

Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence

Info

Publication number
CA2213842A1
CA2213842A1 CA002213842A CA2213842A CA2213842A1 CA 2213842 A1 CA2213842 A1 CA 2213842A1 CA 002213842 A CA002213842 A CA 002213842A CA 2213842 A CA2213842 A CA 2213842A CA 2213842 A1 CA2213842 A1 CA 2213842A1
Authority
CA
Canada
Prior art keywords
dextrorphan
dextromethorphan
urinary incontinence
treatment
estrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002213842A
Other languages
French (fr)
Other versions
CA2213842C (en
Inventor
Frank S. Caruso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Endo Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1996/002809 external-priority patent/WO1996027375A2/en
Publication of CA2213842A1 publication Critical patent/CA2213842A1/en
Application granted granted Critical
Publication of CA2213842C publication Critical patent/CA2213842C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Urinary incontenence is alleviated in a mammal by administering to the mammal a urinary incontinence alleviating amount of dextromethorphan, dextrorphan, their mixtures and/or pharmaceutically acceptable salts, alone or in combination with a pharmacologically active agent such as an anticholinergic sympathomimetic, tricyclic antidepressant, antispasmodic, direct-acting smooth muscle relaxant, estrogen, compound having estrogen-like activity, or any combination of the foregoing.
CA002213842A 1995-03-03 1996-03-01 Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence Expired - Fee Related CA2213842C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39838995A 1995-03-03 1995-03-03
US08/398,389 1995-03-03
PCT/US1996/002809 WO1996027375A2 (en) 1995-03-03 1996-03-01 Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence

Publications (2)

Publication Number Publication Date
CA2213842A1 true CA2213842A1 (en) 1996-09-12
CA2213842C CA2213842C (en) 2006-10-03

Family

ID=37101760

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002213842A Expired - Fee Related CA2213842C (en) 1995-03-03 1996-03-01 Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence

Country Status (1)

Country Link
CA (1) CA2213842C (en)

Also Published As

Publication number Publication date
CA2213842C (en) 2006-10-03

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20150302

MKLA Lapsed

Effective date: 20150302