CA2212744C - Microgelules possedant une ou plusieurs specificites de peptides, leur preparation et leurs utilisations - Google Patents

Microgelules possedant une ou plusieurs specificites de peptides, leur preparation et leurs utilisations Download PDF

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Publication number
CA2212744C
CA2212744C CA002212744A CA2212744A CA2212744C CA 2212744 C CA2212744 C CA 2212744C CA 002212744 A CA002212744 A CA 002212744A CA 2212744 A CA2212744 A CA 2212744A CA 2212744 C CA2212744 C CA 2212744C
Authority
CA
Canada
Prior art keywords
microcapsule
peptide
microcapsules
group
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002212744A
Other languages
English (en)
Other versions
CA2212744A1 (fr
Inventor
Tully J. Speaker
Kenneth J. Sultzbaugh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Temple University of Commonwealth System of Higher Education
Original Assignee
Temple University of Commonwealth System of Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/408,052 external-priority patent/US5686113A/en
Application filed by Temple University of Commonwealth System of Higher Education filed Critical Temple University of Commonwealth System of Higher Education
Publication of CA2212744A1 publication Critical patent/CA2212744A1/fr
Application granted granted Critical
Publication of CA2212744C publication Critical patent/CA2212744C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CA002212744A 1995-03-21 1996-03-18 Microgelules possedant une ou plusieurs specificites de peptides, leur preparation et leurs utilisations Expired - Fee Related CA2212744C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/408,052 US5686113A (en) 1995-03-21 1995-03-21 Microcapsules of predetermined peptide(s) specificity (ies), their preparation and uses
US08/408,052 1995-03-21
PCT/US1996/003666 WO1996029059A1 (fr) 1995-03-21 1996-03-18 Microgelules possedant une ou plusieurs specificites de peptides, leur preparation et leurs utilisations

Publications (2)

Publication Number Publication Date
CA2212744A1 CA2212744A1 (fr) 1996-09-26
CA2212744C true CA2212744C (fr) 2006-10-24

Family

ID=37309491

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002212744A Expired - Fee Related CA2212744C (fr) 1995-03-21 1996-03-18 Microgelules possedant une ou plusieurs specificites de peptides, leur preparation et leurs utilisations

Country Status (1)

Country Link
CA (1) CA2212744C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021002290A1 (fr) * 2019-07-01 2021-01-07 凸版印刷株式会社 Particule composite et procédé de production d'une particule composite

Also Published As

Publication number Publication date
CA2212744A1 (fr) 1996-09-26

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