CA2211808A1 - Method for preparing 4,10-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,7.beta.-dihydroxy-9-oxo-tax-11-en-13.alpha.-yl (2r,3s)-3-benzoylamino-2-hydroxy-3-phenylpropionate trihydrate - Google Patents

Method for preparing 4,10-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,7.beta.-dihydroxy-9-oxo-tax-11-en-13.alpha.-yl (2r,3s)-3-benzoylamino-2-hydroxy-3-phenylpropionate trihydrate

Info

Publication number
CA2211808A1
CA2211808A1 CA002211808A CA2211808A CA2211808A1 CA 2211808 A1 CA2211808 A1 CA 2211808A1 CA 002211808 A CA002211808 A CA 002211808A CA 2211808 A CA2211808 A CA 2211808A CA 2211808 A1 CA2211808 A1 CA 2211808A1
Authority
CA
Canada
Prior art keywords
beta
alpha
diacetoxy
benzoylamino
benzoyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002211808A
Other languages
French (fr)
Other versions
CA2211808C (en
Inventor
Jean-Rene Authelin
Eric Didier
Franck Leveiller
Isabelle Taillepied
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone-Poulenc Rorer S.A.
Jean-Rene Authelin
Eric Didier
Franck Leveiller
Isabelle Taillepied
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9500816A external-priority patent/FR2729666A1/en
Application filed by Rhone-Poulenc Rorer S.A., Jean-Rene Authelin, Eric Didier, Franck Leveiller, Isabelle Taillepied, Aventis Pharma S.A. filed Critical Rhone-Poulenc Rorer S.A.
Publication of CA2211808A1 publication Critical patent/CA2211808A1/en
Application granted granted Critical
Publication of CA2211808C publication Critical patent/CA2211808C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Abstract

A method for preparing 4,10-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,7.beta.-dihydroxy-9-oxo-tax-11-en-yl-13.alpha. (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate trihydrate by crystallisation from a water/alcohol solution.
CA002211808A 1995-01-25 1996-01-23 Method for preparing 4,10-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,7.beta.-dihydroxy-9-oxo-tax-11-en-13.alpha.-yl (2r,3s)-3-benzoylamino-2-hydroxy-3-phenylpropionate trihydrate Expired - Fee Related CA2211808C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9500816A FR2729666A1 (en) 1995-01-25 1995-01-25 PROCESS FOR THE PREPARATION OF (2R, 3S) TRIHYDRATE - BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE OF 4,10-DIACETOXY- 2ALPHA-BENZOYLOXY-5BETA, 20-EPOXY-1,7BETA-DIHYDROXY-9-OX 11-EN-13ALPHA-YLE
FR95/00816 1995-01-25
PCT/FR1996/000104 WO1996022984A1 (en) 1995-01-25 1996-01-23 METHOD FOR PREPARING 4,10-DIACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1,7β-DIHYDROXY-9-OXO-TAX-11-EN-13α-YL (2R,3S)-3-BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE TRIHYDRATE

Publications (2)

Publication Number Publication Date
CA2211808A1 true CA2211808A1 (en) 1996-08-01
CA2211808C CA2211808C (en) 2006-10-10

Family

ID=37111753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002211808A Expired - Fee Related CA2211808C (en) 1995-01-25 1996-01-23 Method for preparing 4,10-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,7.beta.-dihydroxy-9-oxo-tax-11-en-13.alpha.-yl (2r,3s)-3-benzoylamino-2-hydroxy-3-phenylpropionate trihydrate

Country Status (1)

Country Link
CA (1) CA2211808C (en)

Also Published As

Publication number Publication date
CA2211808C (en) 2006-10-10

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