CA2207219A1 - Spacer device and method of it's use - Google Patents
Spacer device and method of it's useInfo
- Publication number
- CA2207219A1 CA2207219A1 CA 2207219 CA2207219A CA2207219A1 CA 2207219 A1 CA2207219 A1 CA 2207219A1 CA 2207219 CA2207219 CA 2207219 CA 2207219 A CA2207219 A CA 2207219A CA 2207219 A1 CA2207219 A1 CA 2207219A1
- Authority
- CA
- Canada
- Prior art keywords
- spacer device
- ofthe
- shows
- valve
- metered dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
- A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0018—Details of inhalators; Constructional features thereof with exhalation check valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
- A61M16/122—Preparation of respiratory gases or vapours by mixing different gases with dilution
- A61M16/125—Diluting primary gas with ambient air
- A61M16/127—Diluting primary gas with ambient air by Venturi effect, i.e. entrainment mixers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
Abstract
An auxiliary spacer device for use with metered dose aerosol devices shown in various embodiments. For use in hospital and home settings, as well as ambulatory use. It incorporates several unique features that significantly improve the therapeutic effects of medications administered in metered dose aerosol form, allows for connection with other standard medical devices for uninterrupted treatment of both adults and children, including infants. The device is user friendly and inexpensive to produce.
Description
~ CA 02207219 1997-06-19 Application for Patent under rule 93 SUBJECT: Spacer Device and method of its use INVENTOR: Leszek Mankowski ABSTRACT:
An auxiliary spacer device for use with metered dose aerosol devices shown in various embo-1iment~. For use in hospital and home settings~ as well as ambulatory use. It incorporates several unique features that ej~njfic~nt1y improve the th~La~euLic effects of m~?~ic~tions atlminietered in metered dose aerosol form, allows for cor~nection with other standard m~ 1 devices for u~ Lell ~led tre~tm~nt of both adults and children, including i~fants. The device is user friendly and inexpensive to produce.
BRIEF DESCRIPTION OF DR~WlNGS:
Figure l:
Shows a spacer device in its pl~r~ d embodiment for use in hospital and home settings, shape and size of elemPnt.e in approximate size and proportions, allowing for connection with standard mPf~ devices, e.g.: m~lsk, oxygen tubing with collection bag, nebulizer, Ventury valve or even between intub~ti-)n tube and a respirator. It is shown in lon3~it~1in~1 cut through a central portion and drawn in approximately l: l scale, giving it total volume of about 600 cc. Description of its el~ ?nte will follow.
Figure 2:
Shows the off-center longitu~lin~1 cut ofthe back portion ofthe spacer device showing the aerosol container l l ~ttsl~he~l to its unique nozz1e 13, "snapped" into its "sparrow-shaped nest" basket 12. The holding arms are not visible in this projection.
Figure 3:
Shows back portion ofthe spacer device viewed from behind with two aerosol cont~iners 11 of same or dilr~Lelll medications "snapped" into position. Holding arms as well as nozzles are visible. The round object located between the nozzles is an inlet port with inlet valve in place.
Figure 4:
Shows back portion of spacer device with two aerosol containers viewed from the top. It illustrates the shape ofthe holding arms, central 9 and lateral 14, ialet port l0.
Figure 5:
Shows details of inlet valve l l, valve ~ e 17 and its holding hooks 18.
Figure 6:
Shows the front part ofthe spacer device in plc;r~ llc;d embodiment form for hospital and home use. It comprises of a "snap on" mout_ piece l, that "sits" on the neck portion of the spacer device. In its mid-portion the mouth piece l shows outlet orifices 3 that are covered by "rubber-band-like" circular ~ lllI)r~e 2 that acts as an outlet valve p~vellL~g T ~ CA 02207219 1997-06-19 air from entering the mouth piece from outside during hls~ildLion. During expiration it is stretched by the force ofthe expired air allowing it to escape through the outlet orifices 3.
It also senes one more unique and important function by providing air flow resistance, causing the patient to exh~le against resistance that is provided through the stretch of the "rubber band" 2, and thus pr~/~llillg the "collapse" of bronchial tubes and secondary l of exhaled air within the bronchial tree. A patient in an ~cthm~tic attack inctin(~tively does the same by pouching his mouth to create a small opening for expiration and slowly expires the air. The neck portion of the spacer device, b~w~ll the mouth piece I and the body 8 is occupied by another unique element that works like a turbine. It consists of a central shaft 6 with tapered ends to which are attached t~ree fins spaced equally along shaft 6 ciL~ el~ce and are twisfed along its long axis. Both the fins 5 and the shaft 6 are stationary and are attached to the front of the neck of the spacer device. On the front portion ofthe turbine sits a dome s~aped valve 4 that has a central opening and is attached to the periphery between the mouth piece I and the neck. To the rear portion of the shaft is ~tf~h~d a screen which catches larger droplets of aerosol mixture passing through it. The function ofthe turbine is to increase the speed and cause a twisting of the aerosol/gas mixture into a narrow vortex-like stream promoting deep penekation ofthe mt?/1ic~tion into the bronchial tree where it is needed. No other spacer device has this feature and all produce a wide and turbulent stream. The body 8 occupies the largest portion of the spacer with volumes between as little as 100 cc to 600 cc that can be fixed or adjustable pending patient size, mP~ ti-)n or method of treatment by a "collapse" mecl~ shown in figure 9. It would then also have m~rkin~ int1i~ tin~
volume in (]ia~;ltll~ "collapsed" positions with name of_edication best suited with the set volume. It is to be made, prer~ldbly, out of clear plastic or acrylic but other m~tçri~l~ may be used. Also various labels or designs with popular characters may be incorporated to make it more attractive and less intimi~1~ting to teenagers and younger children, thus promoting its use.
Figure 7:
Shows the valve in ~lert;rled spacer embodiment, for hospital/home/portable use. It is dome shaped with a central orifice and marginal sk~t, made from stretchable m~teri~l e.g.: rubber, latex.
Figure 8:
Shows secondary embodiment of the outlet valve 4 made of rigid plastic/acrylic m~tPri~
that is also dome shaped with central opening, that has a rim that extends upward as shown in (a) or dowllw~,ds (b). Both versions ofthis valve are not attached and move freelywithin the mouthpiece 1. The function ofthe rhn is to close the outlet ports 3 during hL~ildlion and open them during expiration.
Figure 9:
Shows a p~ led embodiment of a spacer device for portable use in "collapsible" form and diJ~ elll design of the mouthpiece 1 (a) that also incorporates its closing mech~ni~m, col~si~ g oftip portion 15 that slides along the horizontal axis ofthe mouth piece and when in asymmPtrir~l position closes the outlet ofthe mouth piece. The total volume of the spacer body 8 (b) in fully expsln~le~l position is about 250 cc. The rest of the elementx are similar to the prt;r~lled embodiment in hospital/home version, Fig. 1. The resemblance to a water bottle or pop container is not coincidental. It is intçn~1ed to alleviate possible m~-nt by some patients and thus promote its use.
Figure 10:
Shows the pr~r~lled embodiment ofthe spacer device for portable use in fully collapsed form.
Figure 11:
Shows a rubber or plastic cover with central two orifices to accommodate the tips of the aerosol cont~inf~rx, it is to be "snapped on" the back portion ofthe spacer device shown in Fig. 10, to protect the aerosol containers from accidental disengagement from the spacer device and conceal its use further imitz~ting a non-medical device.
Figure 12:
Shows fcont portion ofthe spacer device in the pl~r~ d embodiment for the hospitallhome use during the inspiratory phase.
Figure 13:
Shows front portion ofthe spacer device in the prert;l~ed embodiment for the hospitallhome use during the expiratory phase.
Figure 14/15/16/17:
Shows di~ l embodiment of the back portion of spacer device where the aerosol co..~ , x are attached to one body with two nozzles and settled within the body ofthe spacerdevice. Alsoshownarethedi~ positionsofaerosolcontainers. Ring19 attaches to the base with two nozzles and is int~n-led to ease its removal from spacer device, it also serves for positioning ofthe right/left finger ofthe patient holding the device.
HOW DOES THE DEVICE WORK?
During the ~hm~ti~ attack or exacerbation of asthma the patient seals his lips around the spacer device mouthpiece and breathes continuously in and out from and into the device.
One or mllltirle doses of m~ic~tions are a~lminixtered from aerosol canisters usually Ventolin and Atrovent (trade names). Dependent on ci~ lal.ees oxygen tubing with a collection bag is att~cht?d to the inlet port 10 or tubing with the mixture of oxygen and air provided by the Ventury device. This mixture of medications and oxygen from the body ofthe spacer device is rushed through the turbine device and the valve for which opens allowing the mixture to pass through it and into the patient's bronchial system, as shown inFig.12. Withthelipsof thepatientre...~;..;..gsealedaroundthemouthpiece l,patient e~h~les. This causes the valve 4 to close and rubber-band-like valve 2 to open, allowing the exhaled air to escape through the ports 3 as shown in Fig. 13. This process continues until clinical improvement is achieved. In between the a.1".;.,ixl ~lion ofthe m~ atiQn, the patient continues to inhale and exhale through the spacer device. Depending on ci~ ces, inhsll~ti~n can be continually supported by 100% oxygen with ~tt~-ht?d bag, hllmi~lified oxygen or mixture of oxygen and air provided by Ventury device through the inlet port 10. Iffor any reason the patient cannot hold the spacer device, it can be z~tt~ch~d to the mask by the mollthpiece. The portable pler~ lled embodiment works on similar basis, with the difference that the valve 4 has a dual function opening and closing both orifice 20 (Fig.12) and outlet 3 consecutively during the respiratory phases.
An auxiliary spacer device for use with metered dose aerosol devices shown in various embo-1iment~. For use in hospital and home settings~ as well as ambulatory use. It incorporates several unique features that ej~njfic~nt1y improve the th~La~euLic effects of m~?~ic~tions atlminietered in metered dose aerosol form, allows for cor~nection with other standard m~ 1 devices for u~ Lell ~led tre~tm~nt of both adults and children, including i~fants. The device is user friendly and inexpensive to produce.
BRIEF DESCRIPTION OF DR~WlNGS:
Figure l:
Shows a spacer device in its pl~r~ d embodiment for use in hospital and home settings, shape and size of elemPnt.e in approximate size and proportions, allowing for connection with standard mPf~ devices, e.g.: m~lsk, oxygen tubing with collection bag, nebulizer, Ventury valve or even between intub~ti-)n tube and a respirator. It is shown in lon3~it~1in~1 cut through a central portion and drawn in approximately l: l scale, giving it total volume of about 600 cc. Description of its el~ ?nte will follow.
Figure 2:
Shows the off-center longitu~lin~1 cut ofthe back portion ofthe spacer device showing the aerosol container l l ~ttsl~he~l to its unique nozz1e 13, "snapped" into its "sparrow-shaped nest" basket 12. The holding arms are not visible in this projection.
Figure 3:
Shows back portion ofthe spacer device viewed from behind with two aerosol cont~iners 11 of same or dilr~Lelll medications "snapped" into position. Holding arms as well as nozzles are visible. The round object located between the nozzles is an inlet port with inlet valve in place.
Figure 4:
Shows back portion of spacer device with two aerosol containers viewed from the top. It illustrates the shape ofthe holding arms, central 9 and lateral 14, ialet port l0.
Figure 5:
Shows details of inlet valve l l, valve ~ e 17 and its holding hooks 18.
Figure 6:
Shows the front part ofthe spacer device in plc;r~ llc;d embodiment form for hospital and home use. It comprises of a "snap on" mout_ piece l, that "sits" on the neck portion of the spacer device. In its mid-portion the mouth piece l shows outlet orifices 3 that are covered by "rubber-band-like" circular ~ lllI)r~e 2 that acts as an outlet valve p~vellL~g T ~ CA 02207219 1997-06-19 air from entering the mouth piece from outside during hls~ildLion. During expiration it is stretched by the force ofthe expired air allowing it to escape through the outlet orifices 3.
It also senes one more unique and important function by providing air flow resistance, causing the patient to exh~le against resistance that is provided through the stretch of the "rubber band" 2, and thus pr~/~llillg the "collapse" of bronchial tubes and secondary l of exhaled air within the bronchial tree. A patient in an ~cthm~tic attack inctin(~tively does the same by pouching his mouth to create a small opening for expiration and slowly expires the air. The neck portion of the spacer device, b~w~ll the mouth piece I and the body 8 is occupied by another unique element that works like a turbine. It consists of a central shaft 6 with tapered ends to which are attached t~ree fins spaced equally along shaft 6 ciL~ el~ce and are twisfed along its long axis. Both the fins 5 and the shaft 6 are stationary and are attached to the front of the neck of the spacer device. On the front portion ofthe turbine sits a dome s~aped valve 4 that has a central opening and is attached to the periphery between the mouth piece I and the neck. To the rear portion of the shaft is ~tf~h~d a screen which catches larger droplets of aerosol mixture passing through it. The function ofthe turbine is to increase the speed and cause a twisting of the aerosol/gas mixture into a narrow vortex-like stream promoting deep penekation ofthe mt?/1ic~tion into the bronchial tree where it is needed. No other spacer device has this feature and all produce a wide and turbulent stream. The body 8 occupies the largest portion of the spacer with volumes between as little as 100 cc to 600 cc that can be fixed or adjustable pending patient size, mP~ ti-)n or method of treatment by a "collapse" mecl~ shown in figure 9. It would then also have m~rkin~ int1i~ tin~
volume in (]ia~;ltll~ "collapsed" positions with name of_edication best suited with the set volume. It is to be made, prer~ldbly, out of clear plastic or acrylic but other m~tçri~l~ may be used. Also various labels or designs with popular characters may be incorporated to make it more attractive and less intimi~1~ting to teenagers and younger children, thus promoting its use.
Figure 7:
Shows the valve in ~lert;rled spacer embodiment, for hospital/home/portable use. It is dome shaped with a central orifice and marginal sk~t, made from stretchable m~teri~l e.g.: rubber, latex.
Figure 8:
Shows secondary embodiment of the outlet valve 4 made of rigid plastic/acrylic m~tPri~
that is also dome shaped with central opening, that has a rim that extends upward as shown in (a) or dowllw~,ds (b). Both versions ofthis valve are not attached and move freelywithin the mouthpiece 1. The function ofthe rhn is to close the outlet ports 3 during hL~ildlion and open them during expiration.
Figure 9:
Shows a p~ led embodiment of a spacer device for portable use in "collapsible" form and diJ~ elll design of the mouthpiece 1 (a) that also incorporates its closing mech~ni~m, col~si~ g oftip portion 15 that slides along the horizontal axis ofthe mouth piece and when in asymmPtrir~l position closes the outlet ofthe mouth piece. The total volume of the spacer body 8 (b) in fully expsln~le~l position is about 250 cc. The rest of the elementx are similar to the prt;r~lled embodiment in hospital/home version, Fig. 1. The resemblance to a water bottle or pop container is not coincidental. It is intçn~1ed to alleviate possible m~-nt by some patients and thus promote its use.
Figure 10:
Shows the pr~r~lled embodiment ofthe spacer device for portable use in fully collapsed form.
Figure 11:
Shows a rubber or plastic cover with central two orifices to accommodate the tips of the aerosol cont~inf~rx, it is to be "snapped on" the back portion ofthe spacer device shown in Fig. 10, to protect the aerosol containers from accidental disengagement from the spacer device and conceal its use further imitz~ting a non-medical device.
Figure 12:
Shows fcont portion ofthe spacer device in the pl~r~ d embodiment for the hospitallhome use during the inspiratory phase.
Figure 13:
Shows front portion ofthe spacer device in the prert;l~ed embodiment for the hospitallhome use during the expiratory phase.
Figure 14/15/16/17:
Shows di~ l embodiment of the back portion of spacer device where the aerosol co..~ , x are attached to one body with two nozzles and settled within the body ofthe spacerdevice. Alsoshownarethedi~ positionsofaerosolcontainers. Ring19 attaches to the base with two nozzles and is int~n-led to ease its removal from spacer device, it also serves for positioning ofthe right/left finger ofthe patient holding the device.
HOW DOES THE DEVICE WORK?
During the ~hm~ti~ attack or exacerbation of asthma the patient seals his lips around the spacer device mouthpiece and breathes continuously in and out from and into the device.
One or mllltirle doses of m~ic~tions are a~lminixtered from aerosol canisters usually Ventolin and Atrovent (trade names). Dependent on ci~ lal.ees oxygen tubing with a collection bag is att~cht?d to the inlet port 10 or tubing with the mixture of oxygen and air provided by the Ventury device. This mixture of medications and oxygen from the body ofthe spacer device is rushed through the turbine device and the valve for which opens allowing the mixture to pass through it and into the patient's bronchial system, as shown inFig.12. Withthelipsof thepatientre...~;..;..gsealedaroundthemouthpiece l,patient e~h~les. This causes the valve 4 to close and rubber-band-like valve 2 to open, allowing the exhaled air to escape through the ports 3 as shown in Fig. 13. This process continues until clinical improvement is achieved. In between the a.1".;.,ixl ~lion ofthe m~ atiQn, the patient continues to inhale and exhale through the spacer device. Depending on ci~ ces, inhsll~ti~n can be continually supported by 100% oxygen with ~tt~-ht?d bag, hllmi~lified oxygen or mixture of oxygen and air provided by Ventury device through the inlet port 10. Iffor any reason the patient cannot hold the spacer device, it can be z~tt~ch~d to the mask by the mollthpiece. The portable pler~ lled embodiment works on similar basis, with the difference that the valve 4 has a dual function opening and closing both orifice 20 (Fig.12) and outlet 3 consecutively during the respiratory phases.
Claims
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2207219 CA2207219A1 (en) | 1997-06-19 | 1997-06-19 | Spacer device and method of it's use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2207219 CA2207219A1 (en) | 1997-06-19 | 1997-06-19 | Spacer device and method of it's use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2207219A1 true CA2207219A1 (en) | 1998-12-19 |
Family
ID=4160844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2207219 Abandoned CA2207219A1 (en) | 1997-06-19 | 1997-06-19 | Spacer device and method of it's use |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2207219A1 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001078818A2 (en) * | 2000-04-14 | 2001-10-25 | Trudell Medical International | Nasal inhaler |
| EP1278567A1 (en) * | 2000-05-02 | 2003-01-29 | Salter Labs | Respiratory equipment spacer assembly |
| WO2003084591A1 (en) * | 2002-04-04 | 2003-10-16 | Optinose As | Nasal devices |
| WO2007118800A1 (en) * | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mouthpiece for an inhaler |
| WO2010149144A1 (en) * | 2009-06-24 | 2010-12-29 | Joachim Kern | Turbo-inhaler |
| US8875701B2 (en) | 2006-04-11 | 2014-11-04 | Boehringer Ingelheim International Gmbh | Inhaler |
-
1997
- 1997-06-19 CA CA 2207219 patent/CA2207219A1/en not_active Abandoned
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001078818A2 (en) * | 2000-04-14 | 2001-10-25 | Trudell Medical International | Nasal inhaler |
| WO2001078818A3 (en) * | 2000-04-14 | 2002-04-04 | Trudell Medical Int | Nasal inhaler |
| US6644305B2 (en) | 2000-04-14 | 2003-11-11 | Trudell Medical International | Nasal inhaler |
| EP1278567A1 (en) * | 2000-05-02 | 2003-01-29 | Salter Labs | Respiratory equipment spacer assembly |
| EP1278567A4 (en) * | 2000-05-02 | 2006-04-19 | Salter Labs | Respiratory equipment spacer assembly |
| WO2003084591A1 (en) * | 2002-04-04 | 2003-10-16 | Optinose As | Nasal devices |
| WO2007118800A1 (en) * | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mouthpiece for an inhaler |
| US8281784B2 (en) | 2006-04-11 | 2012-10-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mouthpiece for an inhaler |
| EP2656867A3 (en) * | 2006-04-11 | 2014-01-22 | Boehringer Ingelheim Pharma GmbH & Co. KG | Mouthpiece for an inhalator |
| US8875701B2 (en) | 2006-04-11 | 2014-11-04 | Boehringer Ingelheim International Gmbh | Inhaler |
| WO2010149144A1 (en) * | 2009-06-24 | 2010-12-29 | Joachim Kern | Turbo-inhaler |
| US8820317B2 (en) | 2009-06-24 | 2014-09-02 | Unither Therapeutik Gmbh | Turbo-inhaler |
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Legal Events
| Date | Code | Title | Description |
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| FZDE | Dead |