CA2202345A1 - 2-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cox-2 - Google Patents

2-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cox-2

Info

Publication number
CA2202345A1
CA2202345A1 CA002202345A CA2202345A CA2202345A1 CA 2202345 A1 CA2202345 A1 CA 2202345A1 CA 002202345 A CA002202345 A CA 002202345A CA 2202345 A CA2202345 A CA 2202345A CA 2202345 A1 CA2202345 A1 CA 2202345A1
Authority
CA
Canada
Prior art keywords
cyclopenten
phenyl
methylsulfonyl
treatment
difluorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002202345A
Other languages
English (en)
French (fr)
Inventor
Cameron Black
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Cameron Black
Merck Frosst Canada Inc.
Merck Frosst Canada Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cameron Black, Merck Frosst Canada Inc., Merck Frosst Canada Incorporated filed Critical Cameron Black
Publication of CA2202345A1 publication Critical patent/CA2202345A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002202345A 1997-03-07 1997-04-10 2-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cox-2 Abandoned CA2202345A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4004997P 1997-03-07 1997-03-07
US60/040,049 1997-03-07

Publications (1)

Publication Number Publication Date
CA2202345A1 true CA2202345A1 (en) 1998-09-07

Family

ID=21908813

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002202345A Abandoned CA2202345A1 (en) 1997-03-07 1997-04-10 2-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cox-2

Country Status (5)

Country Link
JP (1) JPH10251220A (ko)
KR (1) KR19980078465A (ko)
CA (1) CA2202345A1 (ko)
IL (1) IL120671A0 (ko)
PL (1) PL319742A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035642A1 (es) * 2000-05-26 2004-06-23 Pharmacia Corp Uso de una composicion de celecoxib para el alivio rapido del dolor
US7642243B2 (en) * 2004-03-31 2010-01-05 Kazuwa Nakao Method of treating arthritis and promoting growth of articular chondrocytes

Also Published As

Publication number Publication date
KR19980078465A (ko) 1998-11-16
JPH10251220A (ja) 1998-09-22
PL319742A1 (en) 1998-09-14
IL120671A0 (en) 1997-08-14

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued