CA2198875A1 - Quinazolinone pharmaceuticals and use thereof - Google Patents
Quinazolinone pharmaceuticals and use thereofInfo
- Publication number
- CA2198875A1 CA2198875A1 CA002198875A CA2198875A CA2198875A1 CA 2198875 A1 CA2198875 A1 CA 2198875A1 CA 002198875 A CA002198875 A CA 002198875A CA 2198875 A CA2198875 A CA 2198875A CA 2198875 A1 CA2198875 A1 CA 2198875A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- hydrogen
- quinazolinone
- pharmaceuticals
- lower alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a pharmaceutical composition for preventing restenosis by the inhibition of vascular smooth muscle cell proliferation, comprising a compound of formula I:
wherein: n=1 or 2 R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy;
R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl as active ingredient therein, or a physiologically acceptable salt thereof, in combination with a pharmaceutically acceptable carrier.
wherein: n=1 or 2 R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy;
R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl as active ingredient therein, or a physiologically acceptable salt thereof, in combination with a pharmaceutically acceptable carrier.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL11083194A IL110831A (en) | 1994-08-31 | 1994-08-31 | Pharmaceutical compositions containing quinazolinone derivatives for preventing restenosis |
IL110831 | 1994-08-31 | ||
PCT/US1995/011186 WO1996006616A1 (en) | 1994-08-31 | 1995-08-29 | Quinazolinone pharmaceuticals and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2198875A1 true CA2198875A1 (en) | 1996-03-07 |
CA2198875C CA2198875C (en) | 2005-11-15 |
Family
ID=35530890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002198875A Expired - Fee Related CA2198875C (en) | 1994-08-31 | 1995-08-29 | Quinazolinone pharmaceuticals and use thereof |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2198875C (en) |
-
1995
- 1995-08-29 CA CA002198875A patent/CA2198875C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2198875C (en) | 2005-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |