CA2198729A1 - Nouvel homologue de la kinase humaine activee par un mitogene (map) - Google Patents

Nouvel homologue de la kinase humaine activee par un mitogene (map)

Info

Publication number
CA2198729A1
CA2198729A1 CA002198729A CA2198729A CA2198729A1 CA 2198729 A1 CA2198729 A1 CA 2198729A1 CA 002198729 A CA002198729 A CA 002198729A CA 2198729 A CA2198729 A CA 2198729A CA 2198729 A1 CA2198729 A1 CA 2198729A1
Authority
CA
Canada
Prior art keywords
smap
polypeptide
leu
sequence
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002198729A
Other languages
English (en)
Inventor
Phillip R. Hawkins
Janice Au-Young
Karl J. Guegler
Craig G. Wilde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2198729A1 publication Critical patent/CA2198729A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des séquences d'acides nucléiques et d'acides aminés qui identifient et codent un nouvel homologue de la kinase humaine activée par un mitogène (SMAP), exprimée par des cellules stomacales humaines. L'invention concerne également des oligomères pour PCR ou des sondes pour hydridation permettant la détection de séquences nucléotidiques codant pour des molécules de SMAP ou analogue, des molécules antisens par rapport aux séquences nucléotidiques codant SMAP, des tests de diagnostic basés sur des molécules d'acide nucléique codant SMAP, des vecteurs d'expression obtenus par génie génétique et des cellules hôtes pour la production de SMAP purifiée, des anticorps capables de se lier spécifiquement à SMAP purifiée, des anticorps capables de se lier spécifiquement à SMAP, ainsi que des agonistes et des inhibiteurs capables de se fixer d'une manière spécifique au polypeptide SMAP.
CA002198729A 1995-06-30 1996-06-28 Nouvel homologue de la kinase humaine activee par un mitogene (map) Abandoned CA2198729A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72295P 1995-06-30 1995-06-30
US60/000,722 1995-06-30

Publications (1)

Publication Number Publication Date
CA2198729A1 true CA2198729A1 (fr) 1997-01-23

Family

ID=21692739

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002198729A Abandoned CA2198729A1 (fr) 1995-06-30 1996-06-28 Nouvel homologue de la kinase humaine activee par un mitogene (map)

Country Status (6)

Country Link
EP (1) EP0781336A1 (fr)
JP (1) JPH10505510A (fr)
AU (1) AU723640B2 (fr)
CA (1) CA2198729A1 (fr)
MX (1) MX9701596A (fr)
WO (1) WO1997002347A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869043A (en) * 1993-09-17 1999-02-09 Smithkline Beecham Corporation Drug binding protein
CA2267656A1 (fr) * 1996-10-09 1998-04-16 Medical Research Council Proteine kinases activees par les mitogenes, polypeptides, polynucleotides et leur utilisation
CA2223075A1 (fr) * 1997-12-02 1999-06-02 Smithkline Beecham Corporation Proteine fixatrice de medicaments
US6897019B1 (en) 1998-04-17 2005-05-24 Tufts College Methods for treating and preventing insulin resistance and related disorders
WO2000006728A2 (fr) * 1998-07-28 2000-02-10 Incyte Pharmaceuticals, Inc. Effecteurs de phosphorylation
US8900811B2 (en) 2000-11-16 2014-12-02 Caliper Life Sciences, Inc. Method and apparatus for generating thermal melting curves in a microfluidic device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU677834B2 (en) * 1993-04-07 1997-05-08 Cancer Research Ventures Limited Methods for screening of substances for therapeutic activityand yeast for use therein

Also Published As

Publication number Publication date
MX9701596A (es) 1997-05-31
AU6405996A (en) 1997-02-05
WO1997002347A1 (fr) 1997-01-23
JPH10505510A (ja) 1998-06-02
AU723640B2 (en) 2000-08-31
EP0781336A1 (fr) 1997-07-02

Similar Documents

Publication Publication Date Title
US5817479A (en) Human kinase homologs
US6190663B1 (en) Human MAP kinase homolog
AU718269B2 (en) A human EDG-2 receptor homolog
US5914393A (en) Human Jak2 kinase
US20020128443A1 (en) Polynucleotides encoding thrombin receptor homologs
AU718311B2 (en) A C5a-like seven transmembrane receptor
US5587306A (en) Phospholipase C homolog
AU723640B2 (en) A human map kinase homolog
US6534275B1 (en) Cellubrevin homologs
US5780268A (en) Chemokine expressed in a mixed lymphocyte reaction
US20060153852A1 (en) Novel human Jak2 kinase
US5840562A (en) DNA encoding human cysteine protease
US5783669A (en) Hyaluronan receptor expressed in human umbilical vein endothelial
US7179898B1 (en) Human vanilloid receptor-like receptor
WO1997006262A1 (fr) Tyrosine phosphatase proteique derivee de basophiles / mastocytes humains
AU728088B2 (en) Novel human cysteine protease
US5738991A (en) Method of detecting elastase IV
AU719815B2 (en) A novel human purinergic P2U receptor
MXPA97007852A (en) Homologo de fosfolipas

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead