CA2197869A1 - Therapeutic agent for cartilaginous diseases - Google Patents
Therapeutic agent for cartilaginous diseasesInfo
- Publication number
- CA2197869A1 CA2197869A1 CA002197869A CA2197869A CA2197869A1 CA 2197869 A1 CA2197869 A1 CA 2197869A1 CA 002197869 A CA002197869 A CA 002197869A CA 2197869 A CA2197869 A CA 2197869A CA 2197869 A1 CA2197869 A1 CA 2197869A1
- Authority
- CA
- Canada
- Prior art keywords
- therapeutic agent
- hgf
- accelerator
- cartilaginous
- diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
The present invention relates to a therapeutic agent for cartilaginous diseases, an accelerator for chondrocyte proliferation and an accelerator for proteoglycan production comprising HGF (hepatocyte growth factor) as an active component, and a treatment method for cartilaginous diseases of human or mammals comprising administering an effective amount of HGF. The active component HGF has an effect to promote the proliferation of chondrocytes and to promote the production of proteoglycan. Therefore, the therapeutic agent and accelerator of the present invention are useful for the prevention and treatment of various disorders caused by cartilaginous diseases.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP218164/1994 | 1994-08-19 | ||
JP21816494A JP3737532B2 (en) | 1994-08-19 | 1994-08-19 | Cartilage disorder treatment |
PCT/JP1995/000121 WO1996005855A1 (en) | 1994-08-19 | 1995-01-30 | Cartilage disease remedy |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2197869A1 true CA2197869A1 (en) | 1996-02-29 |
CA2197869C CA2197869C (en) | 2007-01-02 |
Family
ID=37603346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002197869A Expired - Fee Related CA2197869C (en) | 1994-08-19 | 1995-01-30 | Therapeutic agent for cartilaginous diseases |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2197869C (en) |
-
1995
- 1995-01-30 CA CA002197869A patent/CA2197869C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2197869C (en) | 2007-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20140130 |