CA2191230A1 - Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine - Google Patents

Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine

Info

Publication number
CA2191230A1
CA2191230A1 CA002191230A CA2191230A CA2191230A1 CA 2191230 A1 CA2191230 A1 CA 2191230A1 CA 002191230 A CA002191230 A CA 002191230A CA 2191230 A CA2191230 A CA 2191230A CA 2191230 A1 CA2191230 A1 CA 2191230A1
Authority
CA
Canada
Prior art keywords
deoxyadenosine
halo
inflammatory bowel
bowel disease
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002191230A
Other languages
English (en)
Other versions
CA2191230C (fr
Inventor
Dennis A. Carson
Carlos J. Carrera
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2191230A1 publication Critical patent/CA2191230A1/fr
Application granted granted Critical
Publication of CA2191230C publication Critical patent/CA2191230C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002191230A 1994-05-26 1994-05-26 Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine Expired - Lifetime CA2191230C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/005971 WO1995032718A1 (fr) 1994-05-26 1994-05-26 Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine

Publications (2)

Publication Number Publication Date
CA2191230A1 true CA2191230A1 (fr) 1995-12-07
CA2191230C CA2191230C (fr) 2001-02-27

Family

ID=22242613

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002191230A Expired - Lifetime CA2191230C (fr) 1994-05-26 1994-05-26 Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine

Country Status (4)

Country Link
JP (1) JPH10505323A (fr)
AU (1) AU7470794A (fr)
CA (1) CA2191230C (fr)
WO (1) WO1995032718A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7528247B2 (en) 2001-08-02 2009-05-05 Genzyme Corporation Process for preparing purine nucleosides
US7368423B1 (en) * 2001-12-05 2008-05-06 The Scripps Research Institute Composition and method for treating chronic allograft rejection
EP1551386A4 (fr) * 2002-09-27 2009-03-25 Bioenvision Inc Techniques et compositions destinees au traitement du lupus utilisant la clofarabine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310732A (en) * 1986-02-03 1994-05-10 The Scripps Research Institute 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
WO1989008658A1 (fr) * 1988-03-16 1989-09-21 Scripps Clinic And Research Foundation Derives d'adenine substitues utiles en tant qu'agents therapeutiques

Also Published As

Publication number Publication date
AU7470794A (en) 1995-12-21
CA2191230C (fr) 2001-02-27
JPH10505323A (ja) 1998-05-26
WO1995032718A1 (fr) 1995-12-07

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Legal Events

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MKEX Expiry

Effective date: 20140526