CA2190370A1 - Composition and method for enhancing transdermal electrotransport agent delivery - Google Patents

Composition and method for enhancing transdermal electrotransport agent delivery

Info

Publication number
CA2190370A1
CA2190370A1 CA002190370A CA2190370A CA2190370A1 CA 2190370 A1 CA2190370 A1 CA 2190370A1 CA 002190370 A CA002190370 A CA 002190370A CA 2190370 A CA2190370 A CA 2190370A CA 2190370 A1 CA2190370 A1 CA 2190370A1
Authority
CA
Canada
Prior art keywords
electrotransport
agent
composition
agent delivery
transdermal electrotransport
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002190370A
Other languages
French (fr)
Other versions
CA2190370C (en
Inventor
J. Richard Gyory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1995/008384 external-priority patent/WO1996002232A1/en
Publication of CA2190370A1 publication Critical patent/CA2190370A1/en
Application granted granted Critical
Publication of CA2190370C publication Critical patent/CA2190370C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)

Abstract

A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport delivery device (10) is also provided having a reservoir (16) comprising the agent to be delivered and the electrotransport enhancer of the invention. The electrotransport enhancers increase the electrotransport delivery rate of the agent through the surface while reducing the electrical resistance of the surface during electrotransport of the agent.
CA002190370A 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery Expired - Fee Related CA2190370C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27461994A 1994-07-13 1994-07-13
US08/274,619 1994-07-13
PCT/US1995/008384 WO1996002232A1 (en) 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery

Publications (2)

Publication Number Publication Date
CA2190370A1 true CA2190370A1 (en) 1996-02-01
CA2190370C CA2190370C (en) 2006-10-31

Family

ID=37395777

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002190370A Expired - Fee Related CA2190370C (en) 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery

Country Status (1)

Country Link
CA (1) CA2190370C (en)

Also Published As

Publication number Publication date
CA2190370C (en) 2006-10-31

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed