CA2189690A1 - Novel active peptide and its preparation - Google Patents

Novel active peptide and its preparation

Info

Publication number
CA2189690A1
CA2189690A1 CA002189690A CA2189690A CA2189690A1 CA 2189690 A1 CA2189690 A1 CA 2189690A1 CA 002189690 A CA002189690 A CA 002189690A CA 2189690 A CA2189690 A CA 2189690A CA 2189690 A1 CA2189690 A1 CA 2189690A1
Authority
CA
Canada
Prior art keywords
preparation
active peptide
novel active
val
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002189690A
Other languages
French (fr)
Other versions
CA2189690C (en
Inventor
Wilhelm Amberg
Harald Bernard
Ernst Buschmann
Andreas Haupt
Lothar Janitschke
Bernd Janssen
Ulrich Karl
Andreas Kling
Stefan Muller
Bernd De Potzolli
Kurt Ritter
Marco Thyes
Thomas Zierke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Deutschland GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4415997A external-priority patent/DE4415997A1/en
Application filed by Individual filed Critical Individual
Publication of CA2189690A1 publication Critical patent/CA2189690A1/en
Application granted granted Critical
Publication of CA2189690C publication Critical patent/CA2189690C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed is the compound Me2Val-Val-MeVal-Pro-Pro-NHBzl. HCl. The compound is produced from Z-Val-Val-MeVal-Pro-OR1, wherein Z and R1 have the meanings indicated in the description. The compound disclosed has anti-neoplastic properties.
CA002189690A 1994-05-06 1995-04-26 Novel active peptide and its preparation Expired - Fee Related CA2189690C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4415997A DE4415997A1 (en) 1994-05-06 1994-05-06 New peptide active ingredient and its production
DEP4415997.8 1994-05-06
PCT/EP1995/001577 WO1995030691A1 (en) 1994-05-06 1995-04-26 New peptide active substance and production thereof

Publications (2)

Publication Number Publication Date
CA2189690A1 true CA2189690A1 (en) 1995-11-16
CA2189690C CA2189690C (en) 2007-06-19

Family

ID=38281842

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002189690A Expired - Fee Related CA2189690C (en) 1994-05-06 1995-04-26 Novel active peptide and its preparation

Country Status (1)

Country Link
CA (1) CA2189690C (en)

Also Published As

Publication number Publication date
CA2189690C (en) 2007-06-19

Similar Documents

Publication Publication Date Title
AU3495395A (en) Cyclic cs-1 peptidomimetics, compositions and methods of using the same
AU7636794A (en) Compositions including 1,1,1,2,3,4,4,5,5,5-decafluoropentane
AU7693396A (en) Poly(9,9'-spiro-bisfluorenes), the production and use of same
AU5296593A (en) Concentrated mouthrinse for efficient delivery of antimicrobials
AU6045794A (en) PF1022 derivative cyclic depsipeptide
AU1179795A (en) Improved immunogenic compositions against human gastrin 17
AU9075591A (en) N-halochitosans, their preparation and uses
AU7908098A (en) Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones
CA2270964A1 (en) Benzonaphthyridines as bronchial therapeutics
AU2455295A (en) Protein or polypeptide, process for producing the same, and intermediate compound tehrefor
AU2978697A (en) Novel peptide, process for the production of the same, and use of the same
EP0607012A3 (en) Compressor
AU8321791A (en) Oligosaccharide mixture, and procedure for its manufacturing
AU1915399A (en) Cs-1 peptidomimetics, compositions and methods of using the same
AU4628993A (en) Physiologically active peptide composition
AU5630694A (en) Novel physiologically active compound HS-1 and process for the preparation of the same
AU1441195A (en) Phenylmethyl hexanamides, and the use thereof
AU8876591A (en) Indole-3-methanamines useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents
AU8690491A (en) Electroactive compounds, compositions and devices and methods of making the same
AU7495796A (en) Novel oligopeptides, the preparation and use thereof
MX9605402A (en) New peptide active substance and production thereof.
CA2283450A1 (en) Methods for treatment of scar tissue
AU5087596A (en) Novel beta-agarase and microorganism generating the same
AU4483696A (en) Novel peptides, their production and use
CA2189690A1 (en) Novel active peptide and its preparation

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20150427