CA2186979A1 - Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g - Google Patents

Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g

Info

Publication number
CA2186979A1
CA2186979A1 CA 2186979 CA2186979A CA2186979A1 CA 2186979 A1 CA2186979 A1 CA 2186979A1 CA 2186979 CA2186979 CA 2186979 CA 2186979 A CA2186979 A CA 2186979A CA 2186979 A1 CA2186979 A1 CA 2186979A1
Authority
CA
Canada
Prior art keywords
receptor
cells
activity
protein
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2186979
Other languages
English (en)
Inventor
Michael Dennis
Jean Labrecque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA 2186979 priority Critical patent/CA2186979A1/fr
Priority to CA 2236205 priority patent/CA2236205A1/fr
Priority to AU43742/97A priority patent/AU4374297A/en
Priority to PCT/CA1997/000713 priority patent/WO1998014780A1/fr
Publication of CA2186979A1 publication Critical patent/CA2186979A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 2186979 1996-10-02 1996-10-02 Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g Abandoned CA2186979A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA 2186979 CA2186979A1 (fr) 1996-10-02 1996-10-02 Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g
CA 2236205 CA2236205A1 (fr) 1996-10-02 1997-10-02 Procedes pour determiner la capacite des antagonistes a influer sur l'activite de recepteurs couples a des proteines g
AU43742/97A AU4374297A (en) 1996-10-02 1997-10-02 Methods of testing antagonists for their abilities to affect the activity of g protein-coupled receptors
PCT/CA1997/000713 WO1998014780A1 (fr) 1996-10-02 1997-10-02 Procedes pour determiner la capacite des antagonistes a influer sur l'activite de recepteurs couples a des proteines g

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2186979 CA2186979A1 (fr) 1996-10-02 1996-10-02 Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g

Publications (1)

Publication Number Publication Date
CA2186979A1 true CA2186979A1 (fr) 1998-04-02

Family

ID=4159007

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2186979 Abandoned CA2186979A1 (fr) 1996-10-02 1996-10-02 Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g

Country Status (3)

Country Link
AU (1) AU4374297A (fr)
CA (1) CA2186979A1 (fr)
WO (1) WO1998014780A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104594181A (zh) * 2013-10-31 2015-05-06 索列丹斯-弗莱西奈公司 用于土木工程结构的悬吊系统的缆索中的减振装置

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6682908B1 (en) 1998-07-10 2004-01-27 Merck & Co., Inc. Mouse growth hormone secretagogue receptor
CA2333857A1 (fr) 1998-07-13 2000-01-20 Merck & Co., Inc. Recepteurs et acides nucleiques en rapport avec un secretagogue d'hormone de croissance
GB0217551D0 (en) * 2002-07-30 2002-09-11 Amersham Biosciences Uk Ltd Perturbation effect recognition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4138621A1 (de) * 1991-11-25 1993-06-17 Boehringer Ingelheim Int Verfahren zum screenen von substanzen mit modulierender wirkung auf einen rezeptorabhaengigen zellulaeren signaluebertragungsweg
US5360735A (en) * 1992-01-08 1994-11-01 Synaptic Pharmaceutical Corporation DNA encoding a human 5-HT1F receptor, vectors, and host cells
US5677184A (en) * 1994-04-19 1997-10-14 Takeda Chemical Industries, Ltd. CHO cells that express human LH-RH receptor
CA2135253A1 (fr) * 1994-11-07 1996-05-08 Michael Dennis Depistage de composes grace a une fenetre d'activite independante du message chimique
WO1996041169A1 (fr) * 1995-06-07 1996-12-19 Praecis Pharmaceuticals Incorporated Dosage biologique fonctionnel pour les agonistes et antagonistes des recepteurs couples de proteine g
AU7622396A (en) * 1995-11-22 1997-06-11 Ciba-Geigy Ag Therapeutic agents and screening method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104594181A (zh) * 2013-10-31 2015-05-06 索列丹斯-弗莱西奈公司 用于土木工程结构的悬吊系统的缆索中的减振装置
CN104594181B (zh) * 2013-10-31 2018-12-18 索列丹斯-弗莱西奈公司 用于土木工程结构的悬吊系统的缆索中的减振装置

Also Published As

Publication number Publication date
AU4374297A (en) 1998-04-24
WO1998014780A1 (fr) 1998-04-09

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Legal Events

Date Code Title Description
FZDE Dead