CA2170748A1 - Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis - Google Patents

Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis

Info

Publication number
CA2170748A1
CA2170748A1 CA002170748A CA2170748A CA2170748A1 CA 2170748 A1 CA2170748 A1 CA 2170748A1 CA 002170748 A CA002170748 A CA 002170748A CA 2170748 A CA2170748 A CA 2170748A CA 2170748 A1 CA2170748 A1 CA 2170748A1
Authority
CA
Canada
Prior art keywords
crohn
disease
ulcerative colitis
pharmaceutical preparations
targeted treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002170748A
Other languages
French (fr)
Other versions
CA2170748C (en
Inventor
Ulrich Posanski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2170748A1 publication Critical patent/CA2170748A1/en
Application granted granted Critical
Publication of CA2170748C publication Critical patent/CA2170748C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to a pharmaceutical preparation, which contains an immunosuppressive active agent in dissolved form in a starch capsule, or hard or soft gelatin capsule which has been coated with one or several polymer films.

The invention further relates to a process for the production of the pharmaceutical preparation.
CA002170748A 1993-09-01 1994-08-10 Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis Expired - Fee Related CA2170748C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4329503A DE4329503A1 (en) 1993-09-01 1993-09-01 Pharmaceutical preparations for the targeted treatment of Crohn's disease and ulcerative colitis
DEP4329503.7 1993-09-01
PCT/EP1994/002643 WO1995006464A1 (en) 1993-09-01 1994-08-10 Pharmaceutical preparations for the targeted treatment of morbus crohn and colitis ulcerosa

Publications (2)

Publication Number Publication Date
CA2170748A1 true CA2170748A1 (en) 1995-03-09
CA2170748C CA2170748C (en) 2008-10-28

Family

ID=6496579

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002170748A Expired - Fee Related CA2170748C (en) 1993-09-01 1994-08-10 Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis

Country Status (12)

Country Link
EP (2) EP0716598B1 (en)
JP (1) JP3712005B2 (en)
AT (1) ATE207743T1 (en)
AU (1) AU693470B2 (en)
CA (1) CA2170748C (en)
CY (1) CY2340B1 (en)
DE (2) DE4329503A1 (en)
DK (1) DK0716598T3 (en)
ES (1) ES2166781T3 (en)
NZ (1) NZ271655A (en)
PT (1) PT716598E (en)
WO (1) WO1995006464A1 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197781B1 (en) 1995-07-14 2001-03-06 Novartis Ag Pharmaceutical compositions
US8535713B2 (en) 2007-04-04 2013-09-17 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
US8951570B2 (en) 2007-04-26 2015-02-10 Sigmoid Pharma Limited Manufacture of multiple minicapsules
US9821024B2 (en) 2010-11-25 2017-11-21 Sigmoid Pharma Limited Immunomodulatory compositions
US9878036B2 (en) 2009-08-12 2018-01-30 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
US9950051B2 (en) 2012-07-05 2018-04-24 Sigmoid Pharma Limited Formulations
EP2315583B1 (en) * 2008-07-18 2018-05-09 Yvery Formulation for improving the bioavailability of a hydrophobic molecule
US9999651B2 (en) 2009-05-18 2018-06-19 Sigmoid Pharma Limited Composition comprising oil drops
US10434138B2 (en) 2013-11-08 2019-10-08 Sublimity Therapeutics Limited Formulations
US10993987B2 (en) 2014-11-07 2021-05-04 Sublimity Therapeutics Limited Compositions comprising Cyclosporin

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH686761A5 (en) 1993-05-27 1996-06-28 Sandoz Ag Pharmaceutical formulations.
EP0673646B1 (en) * 1994-03-22 1998-12-02 Nippon Kayaku Co., Ltd. Use of Deoxypergualin in the manufacture of a medicament for the treatment of inflammatory-hyperresponsiveness diseases
GB2303550B (en) * 1994-06-21 1998-07-08 Danbiosyst Uk Colonic drug delivery system
GB9412394D0 (en) 1994-06-21 1994-08-10 Danbiosyst Uk Colonic drug delivery composition
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
JP4221762B2 (en) * 1997-04-11 2009-02-12 アステラス製薬株式会社 Pharmaceutical composition
US6030641A (en) * 1997-06-03 2000-02-29 Uni Colloid Kabushiki Kaisha Sustained release capsule and method for preparing the same
KR100505464B1 (en) 1998-03-26 2005-08-04 후지사와 야꾸힝 고교 가부시키가이샤 Sustained release preparations
AUPP584198A0 (en) * 1998-09-14 1998-10-08 Fujisawa Pharmaceutical Co., Ltd. New use
JP5068401B2 (en) * 1998-09-28 2012-11-07 カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップ Intestinal and colonic delivery using HPMC capsules
US7030219B2 (en) 2000-04-28 2006-04-18 Johns Hopkins University B7-DC, Dendritic cell co-stimulatory molecules
GB0525546D0 (en) * 2005-12-15 2006-01-25 Novartis Ag Organic compounds
WO2010122574A2 (en) * 2009-04-20 2010-10-28 Sun Pharma Advanced Research Company Ltd. Coated capsule
US20210113479A1 (en) * 2018-05-03 2021-04-22 M.W. Encap Limited Dosage forms for delivery of medicines to the lower gastrointestinal tract

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2340060A1 (en) * 1973-08-08 1975-02-20 Scherer Gmbh R P GELATINE RESISTANT CAPSULES AND METHOD FOR MANUFACTURING THEREOF
PH19156A (en) * 1982-02-01 1986-01-15 Sandoz Ltd Dihydrocyclosporin d in the treatment of multiple sclerosis
SE457505B (en) * 1984-01-10 1989-01-09 Lejus Medical Ab LAMINATED ORAL PHARMACEUTICAL COMPOSITION AND PROCEDURES FOR ITS PREPARATION
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition
JPH0211514A (en) * 1988-06-30 1990-01-16 Takara Shuzo Co Ltd Supergualin preparation
US5286730A (en) * 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory disease
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197781B1 (en) 1995-07-14 2001-03-06 Novartis Ag Pharmaceutical compositions
US6599535B2 (en) 1995-07-14 2003-07-29 Novartis Ag Pharmaceutical compositions
US6956043B2 (en) 1995-07-14 2005-10-18 Novartis Ag Pharmaceutical compositions comprising 33-epi-chloro-33-desoxy-ascomycin solid dispersions
US9675558B2 (en) 2007-04-04 2017-06-13 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
US9844513B2 (en) 2007-04-04 2017-12-19 Sigmoid Pharma Limited Oral pharmaceutical composition
US10434140B2 (en) 2007-04-04 2019-10-08 Sublimity Therapeutics Limited Pharmaceutical cyclosporin compositions
US9114071B2 (en) 2007-04-04 2015-08-25 Sigmoid Pharma Limited Oral pharmaceutical composition
US8911777B2 (en) 2007-04-04 2014-12-16 Sigmoid Pharma Limited Pharmaceutical composition of tacrolimus
US8535713B2 (en) 2007-04-04 2013-09-17 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
US10434139B2 (en) 2007-04-04 2019-10-08 Sublimity Therapeutics Limited Oral pharmaceutical composition
US9402788B2 (en) 2007-04-26 2016-08-02 Sigmoid Pharma Limited Manufacture of multiple minicapsules
US8951570B2 (en) 2007-04-26 2015-02-10 Sigmoid Pharma Limited Manufacture of multiple minicapsules
EP2315583B1 (en) * 2008-07-18 2018-05-09 Yvery Formulation for improving the bioavailability of a hydrophobic molecule
US9999651B2 (en) 2009-05-18 2018-06-19 Sigmoid Pharma Limited Composition comprising oil drops
US9878036B2 (en) 2009-08-12 2018-01-30 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
US9821024B2 (en) 2010-11-25 2017-11-21 Sigmoid Pharma Limited Immunomodulatory compositions
US9950051B2 (en) 2012-07-05 2018-04-24 Sigmoid Pharma Limited Formulations
US10434138B2 (en) 2013-11-08 2019-10-08 Sublimity Therapeutics Limited Formulations
US10993987B2 (en) 2014-11-07 2021-05-04 Sublimity Therapeutics Limited Compositions comprising Cyclosporin

Also Published As

Publication number Publication date
CY2340B1 (en) 2004-02-06
AU7535494A (en) 1995-03-22
EP0716598B1 (en) 2001-10-31
ES2166781T3 (en) 2002-05-01
AU693470B2 (en) 1998-07-02
PT716598E (en) 2002-04-29
WO1995006464A1 (en) 1995-03-09
ATE207743T1 (en) 2001-11-15
NZ271655A (en) 1997-09-22
JPH09501939A (en) 1997-02-25
CA2170748C (en) 2008-10-28
EP0716598A1 (en) 1996-06-19
EP1110545A3 (en) 2001-07-04
JP3712005B2 (en) 2005-11-02
EP1110545A2 (en) 2001-06-27
DE4329503A1 (en) 1995-03-02
DE59409929D1 (en) 2001-12-06
DK0716598T3 (en) 2002-02-18

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