CA2165800A1 - Antiallergic imidazoazepines - Google Patents
Antiallergic imidazoazepinesInfo
- Publication number
- CA2165800A1 CA2165800A1 CA002165800A CA2165800A CA2165800A1 CA 2165800 A1 CA2165800 A1 CA 2165800A1 CA 002165800 A CA002165800 A CA 002165800A CA 2165800 A CA2165800 A CA 2165800A CA 2165800 A1 CA2165800 A1 CA 2165800A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- radical
- 6alkyl
- imidazoazepines
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention is concerned with novel imidazoazepines of formula (I), the: pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein each of the dotted lines independently r<;presents an optional bond; -A-B- is a radical of formula -X-CH=CH- (a-1); -CH=CH-X- (a-2); or -CH=CH-CH=CH- (a-3); X represents O, S or NR1; R1 represents hydrogen or C1-6alkyl;
_~ Y is a radical of formula =O (b-1); -OH (b-2); or =N-OH (b-3); and L
represents hydrogen, C1-4alkylcarbonyl, C1-4alkyloxycarbonyl, phenylcarbonyl, C1-6alkyl or C1-6alkyl substituted with C1-4alkyloxycarbonyl, hydroxycarbonyl, aryl, aryloxy or a radical of formula (c), wherein -D-Z. is -S-CH=CH-, -S-CH2-CH2-, -S-CH2-CH2-CH2-, -CH=CH-CH=CH- or -CH2-CH2-CH2-CH2-; and aryl is phenyl or phenyl substituted with halo, hydtnxy or C1-4alkyloxy. Compositions comprising said compounds, processes for preparing the same and the use of these compounds for treating allergic diseases.
_~ Y is a radical of formula =O (b-1); -OH (b-2); or =N-OH (b-3); and L
represents hydrogen, C1-4alkylcarbonyl, C1-4alkyloxycarbonyl, phenylcarbonyl, C1-6alkyl or C1-6alkyl substituted with C1-4alkyloxycarbonyl, hydroxycarbonyl, aryl, aryloxy or a radical of formula (c), wherein -D-Z. is -S-CH=CH-, -S-CH2-CH2-, -S-CH2-CH2-CH2-, -CH=CH-CH=CH- or -CH2-CH2-CH2-CH2-; and aryl is phenyl or phenyl substituted with halo, hydtnxy or C1-4alkyloxy. Compositions comprising said compounds, processes for preparing the same and the use of these compounds for treating allergic diseases.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93202154 | 1993-07-13 | ||
EP93202154.6 | 1993-07-13 | ||
PCT/EP1994/002287 WO1995002600A1 (en) | 1993-07-13 | 1994-07-06 | Antiallergic imidazoazepines |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2165800A1 true CA2165800A1 (en) | 1995-01-26 |
CA2165800C CA2165800C (en) | 2006-03-14 |
Family
ID=36095677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002165800A Expired - Fee Related CA2165800C (en) | 1993-07-13 | 1994-07-06 | Antiallergic imidazoazepines |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2165800C (en) |
-
1994
- 1994-07-06 CA CA002165800A patent/CA2165800C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2165800C (en) | 2006-03-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |