CA2165435C - Nouveaux precurseurs d'antigenes pour le rejet des tumeurs et molecules d'acides nucleiques codant pour ces precurseurs - Google Patents

Nouveaux precurseurs d'antigenes pour le rejet des tumeurs et molecules d'acides nucleiques codant pour ces precurseurs Download PDF

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Publication number
CA2165435C
CA2165435C CA002165435A CA2165435A CA2165435C CA 2165435 C CA2165435 C CA 2165435C CA 002165435 A CA002165435 A CA 002165435A CA 2165435 A CA2165435 A CA 2165435A CA 2165435 C CA2165435 C CA 2165435C
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CA
Canada
Prior art keywords
seq
tumor rejection
rejection antigen
hla
clone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002165435A
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English (en)
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CA2165435A1 (fr
Inventor
Pierre Van Der Bruggen
Thierry Boon-Falleur
Pierre Coulie
Jean-Christophe Renauld
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Ludwig Institute for Cancer Research Ltd
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Ludwig Institute for Cancer Research Ltd
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Publication date
Priority claimed from US08/079,110 external-priority patent/US5571711A/en
Application filed by Ludwig Institute for Cancer Research Ltd filed Critical Ludwig Institute for Cancer Research Ltd
Publication of CA2165435A1 publication Critical patent/CA2165435A1/fr
Application granted granted Critical
Publication of CA2165435C publication Critical patent/CA2165435C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

On décrit une nouvelle famille de précurseurs d'antigènes provoquant le rejet de tumeurs et les molécules d'acides nucléiques qui les codent. Ces précurseurs d'antigènes de rejet de tumeurs sont appelés précurseurs d'antigènes BAGE de rejet de tumeurs et les molécules d'acide nucléiques les codant sont appelées molécules BAGE codantes. On décrit différentes applications diagnostiques et thérapeutiques de ces séquences codantes et de ces molécules précurseurs d'antigènes de rejet des tumeurs.
CA002165435A 1993-06-17 1994-06-10 Nouveaux precurseurs d'antigenes pour le rejet des tumeurs et molecules d'acides nucleiques codant pour ces precurseurs Expired - Fee Related CA2165435C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/079,110 1993-06-17
US08/079,110 US5571711A (en) 1993-06-17 1993-06-17 Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors
US08/196,630 1994-02-15
US08/196,630 US5683886A (en) 1993-06-17 1994-02-15 Tumor rejection antigens which correspond to amino acid sequences in tumor rejection antigen precursor bage, and uses thereof
PCT/US1994/006534 WO1995000159A1 (fr) 1993-06-17 1994-06-10 Peptides isoles formant des complexes avec la molecule mhc du clone hla-c 10 et utilisation de ceux-ci

Publications (2)

Publication Number Publication Date
CA2165435A1 CA2165435A1 (fr) 1994-12-18
CA2165435C true CA2165435C (fr) 2006-08-01

Family

ID=36764221

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002165435A Expired - Fee Related CA2165435C (fr) 1993-06-17 1994-06-10 Nouveaux precurseurs d'antigenes pour le rejet des tumeurs et molecules d'acides nucleiques codant pour ces precurseurs

Country Status (1)

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CA (1) CA2165435C (fr)

Also Published As

Publication number Publication date
CA2165435A1 (fr) 1994-12-18

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