CA2154164A1 - Excipient stabilization of polypeptides treated with organic solvents - Google Patents

Excipient stabilization of polypeptides treated with organic solvents

Info

Publication number
CA2154164A1
CA2154164A1 CA002154164A CA2154164A CA2154164A1 CA 2154164 A1 CA2154164 A1 CA 2154164A1 CA 002154164 A CA002154164 A CA 002154164A CA 2154164 A CA2154164 A CA 2154164A CA 2154164 A1 CA2154164 A1 CA 2154164A1
Authority
CA
Canada
Prior art keywords
organic solvents
polypeptides treated
excipient
stabilization
excipient stabilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002154164A
Other languages
French (fr)
Other versions
CA2154164C (en
Inventor
Jeffrey L. Cleland
Andrew J. S. Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Jeffrey L. Cleland
Andrew J. S. Jones
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jeffrey L. Cleland, Andrew J. S. Jones, Genentech, Inc. filed Critical Jeffrey L. Cleland
Priority claimed from PCT/US1994/001666 external-priority patent/WO1994019020A1/en
Publication of CA2154164A1 publication Critical patent/CA2154164A1/en
Application granted granted Critical
Publication of CA2154164C publication Critical patent/CA2154164C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Methods and compositions for excipient stabilization of dry or aqueous polypeptides treated with organic solvents are disclosed, wherein the polypeptide is admixed with a polyol having a molecular weight less than about 70,000 kD.
CA002154164A 1993-02-23 1994-02-17 Excipient stabilization of polypeptides treated with organic solvents Expired - Lifetime CA2154164C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2142193A 1993-02-23 1993-02-23
US08/021421 1993-02-23
PCT/US1994/001666 WO1994019020A1 (en) 1993-02-23 1994-02-17 Excipient stabilization of polypeptides treated with organic solvents

Publications (2)

Publication Number Publication Date
CA2154164A1 true CA2154164A1 (en) 1994-09-01
CA2154164C CA2154164C (en) 2005-11-22

Family

ID=35474742

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002154164A Expired - Lifetime CA2154164C (en) 1993-02-23 1994-02-17 Excipient stabilization of polypeptides treated with organic solvents

Country Status (1)

Country Link
CA (1) CA2154164C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113801926A (en) * 2021-09-23 2021-12-17 湖北海卓生物科技有限公司 Freeze-drying protective agent for molecular detection reagent and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113801926A (en) * 2021-09-23 2021-12-17 湖北海卓生物科技有限公司 Freeze-drying protective agent for molecular detection reagent and application thereof

Also Published As

Publication number Publication date
CA2154164C (en) 2005-11-22

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20140217