CA2144104A1 - Peptide derivatives having binding activity to modified low density lipoprotein - Google Patents

Peptide derivatives having binding activity to modified low density lipoprotein

Info

Publication number
CA2144104A1
CA2144104A1 CA002144104A CA2144104A CA2144104A1 CA 2144104 A1 CA2144104 A1 CA 2144104A1 CA 002144104 A CA002144104 A CA 002144104A CA 2144104 A CA2144104 A CA 2144104A CA 2144104 A1 CA2144104 A1 CA 2144104A1
Authority
CA
Canada
Prior art keywords
peptide derivatives
low density
binding activity
density lipoprotein
modified low
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002144104A
Other languages
French (fr)
Other versions
CA2144104C (en
Inventor
Toshiki Tanaka
Takefumi Doi
Haruki Nakamura
Takeshi Imanishi
Tatsuhiko Kodama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protein Engineering Research Institute
Original Assignee
Protein Engineering Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protein Engineering Research Institute filed Critical Protein Engineering Research Institute
Publication of CA2144104A1 publication Critical patent/CA2144104A1/en
Application granted granted Critical
Publication of CA2144104C publication Critical patent/CA2144104C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention is directed to peptide derivatives represented by the formula (I):
CA002144104A 1994-11-22 1995-03-07 Peptide derivatives having binding activity to modified low density lipoprotein Expired - Fee Related CA2144104C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6288465A JP2680552B2 (en) 1994-11-22 1994-11-22 Peptide derivative with binding activity for modified low density lipoprotein
JP288465/1994 1994-11-22

Publications (2)

Publication Number Publication Date
CA2144104A1 true CA2144104A1 (en) 1996-05-23
CA2144104C CA2144104C (en) 2001-10-16

Family

ID=17730564

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002144104A Expired - Fee Related CA2144104C (en) 1994-11-22 1995-03-07 Peptide derivatives having binding activity to modified low density lipoprotein

Country Status (5)

Country Link
US (1) US5747451A (en)
EP (1) EP0718308B1 (en)
JP (1) JP2680552B2 (en)
CA (1) CA2144104C (en)
DE (1) DE69513788T2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2452593C (en) 2001-07-12 2015-02-03 Arexis Ab Triple polypeptide complexes
JP5561484B2 (en) * 2008-11-07 2014-07-30 大日本住友製薬株式会社 New affinity carrier
JP6017194B2 (en) * 2012-06-20 2016-10-26 新田ゼラチン株式会社 Treatment or prevention of diseases related to bone, cartilage or skin

Also Published As

Publication number Publication date
DE69513788T2 (en) 2000-06-21
JPH08143591A (en) 1996-06-04
EP0718308A2 (en) 1996-06-26
DE69513788D1 (en) 2000-01-13
JP2680552B2 (en) 1997-11-19
EP0718308B1 (en) 1999-12-08
US5747451A (en) 1998-05-05
EP0718308A3 (en) 1997-03-26
CA2144104C (en) 2001-10-16

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Legal Events

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EEER Examination request
MKLA Lapsed