CA2122470A1 - Oligonucleotides comportant des groupes phosphonate d'aminohydrocarbures - Google Patents

Oligonucleotides comportant des groupes phosphonate d'aminohydrocarbures

Info

Publication number
CA2122470A1
CA2122470A1 CA 2122470 CA2122470A CA2122470A1 CA 2122470 A1 CA2122470 A1 CA 2122470A1 CA 2122470 CA2122470 CA 2122470 CA 2122470 A CA2122470 A CA 2122470A CA 2122470 A1 CA2122470 A1 CA 2122470A1
Authority
CA
Canada
Prior art keywords
oligonucleotide
oligonucleotides
hydrogen
hydrocarbon
markers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2122470
Other languages
English (en)
Inventor
Alan F. Cook
Reza Fathi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmagenics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2122470A1 publication Critical patent/CA2122470A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
CA 2122470 1991-11-25 1992-11-20 Oligonucleotides comportant des groupes phosphonate d'aminohydrocarbures Abandoned CA2122470A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79680491A 1991-11-25 1991-11-25
US796,804 1991-11-25

Publications (1)

Publication Number Publication Date
CA2122470A1 true CA2122470A1 (fr) 1993-06-10

Family

ID=25169100

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2122470 Abandoned CA2122470A1 (fr) 1991-11-25 1992-11-20 Oligonucleotides comportant des groupes phosphonate d'aminohydrocarbures

Country Status (5)

Country Link
EP (1) EP0641354A4 (fr)
JP (1) JPH07501542A (fr)
AU (1) AU3144593A (fr)
CA (1) CA2122470A1 (fr)
WO (1) WO1993011148A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017700A (en) * 1995-08-04 2000-01-25 Bayer Corporation Cationic oligonucleotides, and related methods of synthesis and use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4471113A (en) * 1982-02-03 1984-09-11 The United States Of America As Represented By The Department Of Energy Prodrugs based on phospholipid-nucleoside conjugates

Also Published As

Publication number Publication date
JPH07501542A (ja) 1995-02-16
EP0641354A1 (fr) 1995-03-08
EP0641354A4 (fr) 1996-01-10
AU3144593A (en) 1993-06-28
WO1993011148A1 (fr) 1993-06-10

Similar Documents

Publication Publication Date Title
US5596091A (en) Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides
EP0506242B1 (fr) Méthode et composés pour la synthèse en phase solide d'oligonucléotides et ses analogues
JP4236812B2 (ja) オリゴヌクレオチド類似体
US7572582B2 (en) Oligonucleotide analogues
US6670461B1 (en) Oligonucleotide analogues
US5789562A (en) Nucleotide monomers containing 8-azapurin bases or a derivative thereof, their preparation and their use in making modified olignonucleotides
US7084125B2 (en) Xylo-LNA analogues
KR20020013515A (ko) L-리보-lna 유사체
CA2089668A1 (fr) Oligo(alpha-arabinofuranosylnucleotides) et leurs precurseurs alpha-arabinofuranosyliques
AU8646091A (en) Modified internucleoside linkages
US5646261A (en) 3'-derivatized oligonucleotide analogs with non-nucleotidic groupings, their preparation and use
US6017895A (en) Oligonucleotides possessing zwitterionic moieties
EP0739902B1 (fr) Dérivés ribonucléotidiques de H-phosphonates
CA2122470A1 (fr) Oligonucleotides comportant des groupes phosphonate d'aminohydrocarbures
US6509459B1 (en) Base protecting groups and rapid process for oligonucleotide synthesis
WO1993010140A1 (fr) Oligonucleotides a fractions anioniques modifiees
AU2002325599B2 (en) Oligonucleotide analogues
JP3911703B2 (ja) アンチセンス核酸同族体
WO1994015620A1 (fr) Nouveaux oligonucleotides modifies par des groupes de pontage non nucleotidiques
WO1995031572A1 (fr) Oligonucleotides contenant une fraction phosphonate d'aminohydrocarbure et utilisation desdits oligonucleotides
WO1998033806A1 (fr) Groupes de protection de bases et procede de synthese d'oligonucleotides

Legal Events

Date Code Title Description
FZDE Dead