CA2119109A1 - Bioadhesive ophthalmic insert - Google Patents
Bioadhesive ophthalmic insertInfo
- Publication number
- CA2119109A1 CA2119109A1 CA002119109A CA2119109A CA2119109A1 CA 2119109 A1 CA2119109 A1 CA 2119109A1 CA 002119109 A CA002119109 A CA 002119109A CA 2119109 A CA2119109 A CA 2119109A CA 2119109 A1 CA2119109 A1 CA 2119109A1
- Authority
- CA
- Canada
- Prior art keywords
- bioadhesive
- biocompatible polymer
- ophthalmic insert
- insert
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
A bioadhesive ophthalmic insert is described which is intended more particularly for the prolonged and controlled release of a medicinal substance. The insert comprises a composite polymeric material matrix in which the medicinal substance is incorporated.
The composite polymeric material matrix comprises a water-soluble biocompatible polymer and a bioadhesive biocompatible polymer and, where applicable, a water-insoluble biocompatible polymer.
The composite polymeric material matrix comprises a water-soluble biocompatible polymer and a bioadhesive biocompatible polymer and, where applicable, a water-insoluble biocompatible polymer.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002119109A CA2119109C (en) | 1994-03-15 | 1994-03-15 | Bioadhesive ophthalmic insert |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002119109A CA2119109C (en) | 1994-03-15 | 1994-03-15 | Bioadhesive ophthalmic insert |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2119109A1 true CA2119109A1 (en) | 1995-09-16 |
CA2119109C CA2119109C (en) | 2002-11-12 |
Family
ID=4153174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002119109A Expired - Fee Related CA2119109C (en) | 1994-03-15 | 1994-03-15 | Bioadhesive ophthalmic insert |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2119109C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7678827B2 (en) | 2002-07-15 | 2010-03-16 | Alcon, Inc. | Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use |
-
1994
- 1994-03-15 CA CA002119109A patent/CA2119109C/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7678827B2 (en) | 2002-07-15 | 2010-03-16 | Alcon, Inc. | Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use |
US8178576B2 (en) | 2002-07-15 | 2012-05-15 | Novartis Ag | Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use |
Also Published As
Publication number | Publication date |
---|---|
CA2119109C (en) | 2002-11-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |