CA2116138C - Methodes et compositions pour l'attenuation du rejet de xenogreffes medie par des anticorps chez des receveurs humains - Google Patents

Methodes et compositions pour l'attenuation du rejet de xenogreffes medie par des anticorps chez des receveurs humains Download PDF

Info

Publication number
CA2116138C
CA2116138C CA002116138A CA2116138A CA2116138C CA 2116138 C CA2116138 C CA 2116138C CA 002116138 A CA002116138 A CA 002116138A CA 2116138 A CA2116138 A CA 2116138A CA 2116138 C CA2116138 C CA 2116138C
Authority
CA
Canada
Prior art keywords
fwdarw
beta
gal
alpha
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002116138A
Other languages
English (en)
Other versions
CA2116138A1 (fr
Inventor
Heather A. Good
David K. C. Cooper
Andrew J. Malcolm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alberta Research Council
Integris Baptist Medical Center Inc
Original Assignee
Alberta Research Council
Integris Baptist Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alberta Research Council, Integris Baptist Medical Center Inc filed Critical Alberta Research Council
Priority claimed from PCT/US1992/007071 external-priority patent/WO1993003735A1/fr
Publication of CA2116138A1 publication Critical patent/CA2116138A1/fr
Application granted granted Critical
Publication of CA2116138C publication Critical patent/CA2116138C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002116138A 1991-08-23 1992-08-21 Methodes et compositions pour l'attenuation du rejet de xenogreffes medie par des anticorps chez des receveurs humains Expired - Fee Related CA2116138C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74952991A 1991-08-23 1991-08-23
US07/749,529 1991-08-23
PCT/US1992/007071 WO1993003735A1 (fr) 1991-08-23 1992-08-21 Procedes et compositions d'attenuation de rejet de xenogrephe induit par les anticorps chez les receveurs humains

Publications (2)

Publication Number Publication Date
CA2116138A1 CA2116138A1 (fr) 1993-03-04
CA2116138C true CA2116138C (fr) 2006-04-04

Family

ID=36143210

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002116138A Expired - Fee Related CA2116138C (fr) 1991-08-23 1992-08-21 Methodes et compositions pour l'attenuation du rejet de xenogreffes medie par des anticorps chez des receveurs humains

Country Status (1)

Country Link
CA (1) CA2116138C (fr)

Also Published As

Publication number Publication date
CA2116138A1 (fr) 1993-03-04

Similar Documents

Publication Publication Date Title
EP0661980B1 (fr) Procedes et compositions d'attenuation de rejet de xenogrephe induit par les anticorps chez les receveurs humains
Cooper et al. Identification of α-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man
Garratty Modulating the red cell membrane to produce universal/stealth donor red cells suitable for transfusion
Garratty Progress in modulating the RBC membrane to produce transfusable universal/stealth donor RBCs
Baquerizo et al. CHARACTERIZATION OF HUMAN XENOREACTIVE ANTIBODIES IN LIVER FAILURE PATIENTS EXPOSED TO PIG HEPATOCYTES AFTER BIOARTIFICIAL LIVER TREATMENT: An Ex Vivo Model of Pig to Human Xenotransplantation: 1, 2
Nyame et al. Schistosoma mansoniInfection in Humans and Primates Induces Cytolytic Antibodies to Surface LexDeterminants on Myeloid Cells
Breimer Gal/non‐Gal antigens in pig tissues and human non‐Gal antibodies in the GalT‐KO era 1
WO1999016318A1 (fr) Cellule antigene reduite et ses utilisations
EP0147689B1 (fr) Méthode d'induction d'immunocytes antitumoraux, procédé de production d'immunocytes antitumoraux et immunocytes antitumoraux produits par le procédé
Chen et al. Carbohydrates in transplantation
Zhu BINDING OF HUMAN NATURAL ANTIBODIES TO NONαGal XENOANTIGENS ON PORCINE ERYTHROCYTES1
US5977079A (en) Compositions for attenuating antibody- mediated xenograft rejection in human recipients
Spitalnik et al. Anti-My-28, an antigranulocyte mouse monoclonal antibody, binds to a sugar sequence in lacto-N-neotetraose
Breimer et al. The structural complexity and animal tissue distribution of N-glycolylneuraminic acid (Neu5Gc)-terminated glycans. Implications for their immunogenicity in clinical xenografting
CA2116138C (fr) Methodes et compositions pour l'attenuation du rejet de xenogreffes medie par des anticorps chez des receveurs humains
Rydberg et al. α-Gal epitopes in animal tissue glycoproteins and glycolipids
Magnusson et al. Release of pig leukocytes during pig kidney perfusion and characterization of pig lymphocyte carbohydrate xenoantigens
Bornemann et al. Consideration of potential immunological problems in the application of xenogenic hybrid liver support
WO2004050897A2 (fr) Procedes de preparation de globules rouges a masquage d'antigene et hemolyse reduite au moyen de serums
IL120453A (en) Anti-rejection drug-mediated drug of foreign implant rejection
Yogeeswaran Surface glycolipid and glycoprotein antigens
Zehavi et al. Binding of Leishmania promastigotes to macrophages
Aspeslet et al. Identification of porcine membrane antigens involved in the cytotoxic response mediated by human xenoreactive antibodies
Magnusson et al. Expression of carbohydrate xenoantigens on porcine peripheral nerve
EP0847280B1 (fr) Compositions et leurs utilisations contre le rejet hyperaigue de xenogreffes et contre certaines maladies

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed