CA2115069A1 - Method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material - Google Patents

Method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material

Info

Publication number
CA2115069A1
CA2115069A1 CA 2115069 CA2115069A CA2115069A1 CA 2115069 A1 CA2115069 A1 CA 2115069A1 CA 2115069 CA2115069 CA 2115069 CA 2115069 A CA2115069 A CA 2115069A CA 2115069 A1 CA2115069 A1 CA 2115069A1
Authority
CA
Canada
Prior art keywords
removal
rate
virus
filter
organic material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2115069
Other languages
French (fr)
Other versions
CA2115069C (en
Inventor
Gerhard Becker
Marcel P. Larson
Reiner Heidl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanorell Pharma GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6437804&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2115069(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2115069A1 publication Critical patent/CA2115069A1/en
Application granted granted Critical
Publication of CA2115069C publication Critical patent/CA2115069C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/022—Filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/22—Controlling or regulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10—Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/102—Detection of leaks in membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

In order to check the rate of removal of pyrogenic substances, in particular viruses, from organic material, the material to be purified is passed through an ultra-filter or an ultra-filtration unit whose virus-removal rate has already been determined by passing viruses of the $i(Leviviridae) family or other, comparable, small bacteriophages through the filter or filtration unit, the virus titre determined before and after the filtration operation and the virus-removal rate thus calculated. Before or after determining the virus-removal rate, a given pressure is applied to the filter or filtration unit in a gas pressure-hold test, and the decrease in pressure over a given period measured. After filtration of the biological material, the rate of virus removal by the filter is checked by repeating the pressure-hold test.
CA002115069A 1991-08-06 1992-08-05 Method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material Expired - Fee Related CA2115069C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4126034A DE4126034C1 (en) 1991-08-06 1991-08-06
DEP4126034.1 1991-08-06
PCT/DE1992/000653 WO1993002714A1 (en) 1991-08-06 1992-08-05 Method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material

Publications (2)

Publication Number Publication Date
CA2115069A1 true CA2115069A1 (en) 1993-02-18
CA2115069C CA2115069C (en) 2000-12-19

Family

ID=6437804

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002115069A Expired - Fee Related CA2115069C (en) 1991-08-06 1992-08-05 Method of checking the rate of removal of pyrogenic substances, in particular viruses, from organic material

Country Status (6)

Country Link
EP (1) EP0599981B1 (en)
AT (1) ATE147274T1 (en)
AU (1) AU2473392A (en)
CA (1) CA2115069C (en)
DE (2) DE4126034C1 (en)
WO (1) WO1993002714A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4429558A1 (en) * 1994-08-19 1996-02-22 Sanorell Pharma Gmbh & Co Process for the production of infection-free pharmaceutical preparations and / or foods from infectious material
DE10003811A1 (en) * 2000-01-28 2001-08-09 Sanorell Pharma Gmbh & Co Process for the production of a serum-containing culture medium for cells and its use
FR2839897B1 (en) * 2002-05-24 2004-07-09 Air Liquide METHOD FOR IMPACT SEPARATION OF VIABLE AND REVIVISCENT PARTICLES FROM A GAS OR GAS MIXTURE CONTAINING THE SAME, DEVICE AND TEST BENCH IMPLEMENTED

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808315A (en) * 1986-04-28 1989-02-28 Asahi Kasei Kogyo Kabushiki Kaisha Porous hollow fiber membrane and a method for the removal of a virus by using the same
DE4003543A1 (en) * 1990-02-06 1991-08-08 Orpegen Med Molekularbioforsch METHOD FOR TREATING VIRUSES IN SOLUTIONS AND DETERMINING THE TREATMENT RATE OF VIRUSES

Also Published As

Publication number Publication date
ATE147274T1 (en) 1997-01-15
DE59207860D1 (en) 1997-02-20
CA2115069C (en) 2000-12-19
EP0599981B1 (en) 1997-01-08
DE4126034C1 (en) 1992-09-10
AU2473392A (en) 1993-03-02
WO1993002714A1 (en) 1993-02-18
EP0599981A1 (en) 1994-06-08

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed