CA2105665A1 - Diphenylthiazole Derivative - Google Patents

Diphenylthiazole Derivative

Info

Publication number
CA2105665A1
CA2105665A1 CA 2105665 CA2105665A CA2105665A1 CA 2105665 A1 CA2105665 A1 CA 2105665A1 CA 2105665 CA2105665 CA 2105665 CA 2105665 A CA2105665 A CA 2105665A CA 2105665 A1 CA2105665 A1 CA 2105665A1
Authority
CA
Canada
Prior art keywords
group
halogenated
hydrogen atom
lower alkanesulfonyl
alkanesulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2105665
Other languages
French (fr)
Other versions
CA2105665C (en
Inventor
Masaru Saita
Hisataka Inoue
Kouichi Ikesue
Noriyuki Fujimoto
Ikuo Shinohara
Yasuaki Taniguchi
Yoshiki Deguchi
Hidenao Minami
Kanji Noda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Masaru Saita
Hisataka Inoue
Kouichi Ikesue
Noriyuki Fujimoto
Ikuo Shinohara
Yasuaki Taniguchi
Yoshiki Deguchi
Hidenao Minami
Kanji Noda
Hisamitsu Pharmaceuticals Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Masaru Saita, Hisataka Inoue, Kouichi Ikesue, Noriyuki Fujimoto, Ikuo Shinohara, Yasuaki Taniguchi, Yoshiki Deguchi, Hidenao Minami, Kanji Noda, Hisamitsu Pharmaceuticals Co., Inc. filed Critical Masaru Saita
Priority to CA 2105665 priority Critical patent/CA2105665C/en
Publication of CA2105665A1 publication Critical patent/CA2105665A1/en
Application granted granted Critical
Publication of CA2105665C publication Critical patent/CA2105665C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel diphenylthiazole derivatives having the following general formula (I):

(see fig. I) (I) wherein m and n are independently 1 or 2; R1 and R~
each represent a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylsulfenyl group, a nitro group, an amino group, a methanesulfonyloxy group or a halogen atom; A1 represents a lower alkanesulfonyl group, a halogenated lower alkanesulfonyl group, or a halogenated or haloalkylated benzenesulfonyl group; and A~ represents a hydrogen atom, a lower alkanesulfonyl group, a halogenated lower alkanesulfonyl group, or a lower alkyl group;
and pharmaceutically acceptable salts thereof; are efficacious as drugs having antiinflammatory, analgesic, antiallergic, uricosuric or platelet aggregation inhibiting effects.
CA 2105665 1991-03-07 1991-03-07 Diphenylthiazole derivative Expired - Fee Related CA2105665C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2105665 CA2105665C (en) 1991-03-07 1991-03-07 Diphenylthiazole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2105665 CA2105665C (en) 1991-03-07 1991-03-07 Diphenylthiazole derivative

Publications (2)

Publication Number Publication Date
CA2105665A1 true CA2105665A1 (en) 1992-09-08
CA2105665C CA2105665C (en) 1997-08-19

Family

ID=4152273

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2105665 Expired - Fee Related CA2105665C (en) 1991-03-07 1991-03-07 Diphenylthiazole derivative

Country Status (1)

Country Link
CA (1) CA2105665C (en)

Also Published As

Publication number Publication date
CA2105665C (en) 1997-08-19

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed