CA2104976A1 - Separation de plasma ou de serum a partir de sang total a l'aide d'une composante se liant aux globules rouges et d'un polymere contenant de multiples sites cationiques - Google Patents

Separation de plasma ou de serum a partir de sang total a l'aide d'une composante se liant aux globules rouges et d'un polymere contenant de multiples sites cationiques

Info

Publication number
CA2104976A1
CA2104976A1 CA 2104976 CA2104976A CA2104976A1 CA 2104976 A1 CA2104976 A1 CA 2104976A1 CA 2104976 CA2104976 CA 2104976 CA 2104976 A CA2104976 A CA 2104976A CA 2104976 A1 CA2104976 A1 CA 2104976A1
Authority
CA
Canada
Prior art keywords
red blood
lectin
layer
whole blood
cell binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2104976
Other languages
English (en)
Inventor
Stephan D. Daubney
Sandra G. Devenny
Donna J. Phelps
James B. Johnston
John L. Palmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enzymatics Inc
Original Assignee
Enzymatics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enzymatics Inc filed Critical Enzymatics Inc
Publication of CA2104976A1 publication Critical patent/CA2104976A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
CA 2104976 1992-09-02 1993-08-27 Separation de plasma ou de serum a partir de sang total a l'aide d'une composante se liant aux globules rouges et d'un polymere contenant de multiples sites cationiques Abandoned CA2104976A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94026692A 1992-09-02 1992-09-02
US07/940,266 1992-09-02

Publications (1)

Publication Number Publication Date
CA2104976A1 true CA2104976A1 (fr) 1994-03-03

Family

ID=25474530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2104976 Abandoned CA2104976A1 (fr) 1992-09-02 1993-08-27 Separation de plasma ou de serum a partir de sang total a l'aide d'une composante se liant aux globules rouges et d'un polymere contenant de multiples sites cationiques

Country Status (3)

Country Link
EP (1) EP0597577A1 (fr)
JP (1) JPH075173A (fr)
CA (1) CA2104976A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996031270A1 (fr) * 1995-04-07 1996-10-10 Lxn Corporation Methode et dispositifs de separation du sang entier

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582907A (en) * 1994-07-28 1996-12-10 Pall Corporation Melt-blown fibrous web
EP0772484B1 (fr) 1994-07-28 2008-02-27 Pall Corporation Bande fibreuse pour traiter un fluide
ES2268706T3 (es) * 1995-05-09 2007-03-16 Beckman Coulter, Inc. Dispositivos y procedimientos para separar componentes celulares de la sangre de la porcion liquida de la sangre.
IL135275A0 (en) * 2000-03-27 2001-05-20 Shapira Hagit Blood transfusion method and device
JP4191051B2 (ja) 2002-02-27 2008-12-03 三光純薬株式会社 血漿又は血清分離具
WO2009068027A1 (fr) * 2007-11-26 2009-06-04 Atonomics A/S Dispositif de séparation et de détection
US9383293B2 (en) 2010-04-23 2016-07-05 Boehringer Ingelheim Microparts Gmbh Device for plasma separation by means of a central channel structure
US20150258267A1 (en) * 2012-08-08 2015-09-17 Koninklijke Philips N.V. Plasma separation using a drop of blood
JP5931776B2 (ja) * 2013-02-26 2016-06-08 シスメックス株式会社 体液収集体保持シートの支持キット、体液収集体の保護方法、及び体液収集体の取出方法
WO2016073823A1 (fr) * 2014-11-07 2016-05-12 The Johns Hopkins University Séparation de plasma de sans total assistée par agrégation
JP6080236B2 (ja) * 2014-12-09 2017-02-15 花王株式会社 生理用品及び生理用品用処理剤
AU2016229837B2 (en) * 2015-03-10 2018-05-24 Becton, Dickinson And Company Biological fluid micro-sample management device
JP6729558B2 (ja) * 2015-03-31 2020-07-22 ソニー株式会社 電気的特性測定装置、電気的特性測定方法、血液状態解析システム、及び該方法をコンピューターに実現させるための電気的特性測定用プログラム
CN106442079B (zh) * 2016-08-31 2020-04-14 杭州博拓生物科技股份有限公司 一种滤血样品垫及其制备方法
CA3038003A1 (fr) * 2016-10-07 2018-04-12 Acousort Ab Procede et systeme de mesures optiques ou electriques dans des fluides disperses
CN118202245A (zh) * 2021-09-10 2024-06-14 奎多公司 用于全血测定的凝集剂、装置和方法
JPWO2023048115A1 (fr) * 2021-09-21 2023-03-30
CA3235139A1 (fr) * 2021-10-29 2023-05-04 Trustees Of Tufts College Kits, articles et methodes de separation du sang

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3441149A1 (de) * 1984-11-10 1986-05-15 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur vollblutauftrennung
DE3508427A1 (de) * 1985-03-09 1986-09-11 Merck Patent Gmbh, 6100 Darmstadt Mittel und verfahren zur abtrennung von plasma oder serum aus vollblut
US4933092A (en) * 1989-04-07 1990-06-12 Abbott Laboratories Methods and devices for the separation of plasma or serum from whole blood

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996031270A1 (fr) * 1995-04-07 1996-10-10 Lxn Corporation Methode et dispositifs de separation du sang entier
US5725774A (en) * 1995-04-07 1998-03-10 Lxn Corp. Whole blood separation method and devices using the same
US5762871A (en) * 1995-04-07 1998-06-09 Lxn Corp. Multi-layer test device for analyzing the concentration of analyte in a blood sample

Also Published As

Publication number Publication date
EP0597577A1 (fr) 1994-05-18
JPH075173A (ja) 1995-01-10

Similar Documents

Publication Publication Date Title
CA2104976A1 (fr) Separation de plasma ou de serum a partir de sang total a l'aide d'une composante se liant aux globules rouges et d'un polymere contenant de multiples sites cationiques
US4933092A (en) Methods and devices for the separation of plasma or serum from whole blood
US5432054A (en) Method for separating rare cells from a population of cells
CA2014119C (fr) Methodes et dispositifs pour la separation du plasma ou du serum du sang entier, collecte de plasma ou de serum et reactifs
US5064541A (en) Devices and methods for the collection of a predetermined volume of plasma or serum
EP0739229B1 (fr) Milieu de gradient de densite pour la separation de cellules
US5096809A (en) Whole blood assays using porous membrane support devices
US4369117A (en) Serum separating method and apparatus
US8722423B2 (en) Assay method utilizing capillary transport on non-porous substrates
US5423989A (en) Plasma forming device
JP2628792B2 (ja) 改良されたリガンドのアッセイ
EP0755719B1 (fr) Essai d'agglutination en colonnes et dispositif
US8097171B2 (en) Method of separating a fluid fraction from whole blood
EP1745290B1 (fr) Utilisation de ferrofluides pour le phenotypage sanguin et applications derivees
US4965187A (en) Method and apparatus for assaying whole blood
EP0263978B1 (fr) Méthode et dispositif pour tester le sang intégral
EP0628816B1 (fr) Particule pour améliorer la coagulation dans des tubes pour le prélèvement du sang par activation de deux voies, dispositif pour le prélèvement du sang et méthode pour produire les particules
CA2113101A1 (fr) Trousses diagnostiques et methodes de numeration des granulocytes
EP1064556A1 (fr) Methode en phase solide pour determinations d'antigenes et d'anticorps en serologie des groupes sanguins et kit de test
US5192663A (en) Article having an organic dye and a monolayer of dried mammalian cells and a method for utilizing the article
EP2340123B1 (fr) Cuve de réaction apte à détecter des agglutinats érythrocytaires chargées d'anticorps, procédé pour la détection des agglutinats érythrocytaires chargées d'anticorps et coffret d'éléments
WO2015014974A1 (fr) Média filtrant à feuille plane pour la séparation de plasma ou de sérum à partir de sang total
JP4260980B2 (ja) 検体の処理方法
JP2000292420A (ja) 血清または血漿採取方法及び血清もしくは血漿分離試薬
JPH0483166A (ja) 体液の処理方法

Legal Events

Date Code Title Description
FZDE Dead