CA2097919A1 - Jet injector for mass inoculation - Google Patents

Jet injector for mass inoculation

Info

Publication number
CA2097919A1
CA2097919A1 CA002097919A CA2097919A CA2097919A1 CA 2097919 A1 CA2097919 A1 CA 2097919A1 CA 002097919 A CA002097919 A CA 002097919A CA 2097919 A CA2097919 A CA 2097919A CA 2097919 A1 CA2097919 A1 CA 2097919A1
Authority
CA
Canada
Prior art keywords
medicament
chamber
gas
jet injector
injector device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002097919A
Other languages
French (fr)
Inventor
Peter Elliott Rosenzweig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
COLUMBIA PACIFIC TECHNOLOGIES Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2097919A1 publication Critical patent/CA2097919A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053Media being expelled from injector by pressurised fluid or vacuum

Abstract

ABSTRACT

A needleless jet injector device (100) for use with separate storage tanks of gas and medicament, the device (100) comprising a body having a gas inlet for connection to the gas storage tank and a medicament inlet for connection to the medicament storage tank, an active chamber for receiving medicament and having a jet nozzle (1) through which the medicament is discharged, the active chamber further receiving a piston head (3) movable to force the medicament through the nozzle (1) upon movement of the piston head (3) in the chamber towards the nozzle (1), the piston head (3) being connected to a piston (9) movable within a gas chamber (24) within the body, and means (14, 15, 20) for selectively allowing gas to enter the gas chamber (24) so as to move the piston (9) and the piston head (3) to discharge medicament through the nozzle (1).

Description

2~97~
W O 92~1022~ ~ . PCT/AU~1~00566 JET l 1QR QR ~S IN~C~LATION
BA~K~RQ~LND OF THE_LN.VENTION
The presen~ lnvention per~ains to needleless injectors and ~ore particularly to a needleless ~e~ injector for mass lnoculation.
SUMMARY OF THE INVENl~LON
~t i5 ~n ob~ect of ~he present invention to provide ~ iet injector which facilit~tes mass ad~inistration, by in~ection, of ~eterinary or human ~edicat~on from a bulk supply.
Accordlngly, the ln~ention provides, in a first aspe~t, a n~edleles5 Jet inje~t~r device ~or use with a supply of gas under pressure and medlcament, th~ devlce comprist~g a body ha~tng a gas lnlet for sai~ ~as and a medicament iniet ~o~ said medicament, a ~irst chambe~
communicatjng w~th said medicament inlet and havin~ an out1et, ~ jet nozzle eommunicating wi~h said outlet so ~s to receive medtcament, under pressur~, ~or ~njection, a second chamber communicatlng with said ~as inle.~, a ~irst piston at least partly defining sald flrst cha~ber zn~
mova41e ~o vary the volume thereo~ so as to ~eliver a dose of medieament und~r pressurQ ~o sa1d ou~l~k, a second piston ~t least partly de~tning sald second ~h~mber and ~vable to ~ary the volume thereof, connection means ~oupllng th~ first and second plstons so that movement of said second plston causes movement of sai~ first piston, medicament flow control means to operatively restrict flow of the medicamen~ ~rom the medicament inlet to said ~rs~ chamber, and control me~ns to ~egulate the flow o~ gas to said s~cond chamber to cause moYem~nt of sald second pis~on ~nd therefor movement of said first pis~on.
In a preferred embodiment, the medication is carrled by a ~ckpac~
which suppll~s ~he ln~ector. The inj~c~or p~eferably au~omatically r~l4ads a medication cylinder upon th~ releas~ of a trigg~r m2chanlsm at the c~mpletlon of ~ch injection.
3~ It ts ~r~fPrr~d that tho do~ago bo roa~l ly ad justablo by me~n~ o~
piston st~ok~ ~djust2r.

One embo~ment of a jet injector accordin~ to the present ~nv~ntion will now be moro fully describe~, ~y way ~f ex~mDle, with reference to 35 the draw1n~s~ of ~hi~h~
Floure 1 ~* A l~r-nes-s~tion~1 vi~w of ~n~ ~mbc~d~ ent Of A jet in~ec~or d~cordtng to the present inventlon; ar~d 1 L610 nN 98bS19~ ~ 19 ~IOSn~`d~ OSn~dS 90 l1 ~661 ~In~ l w 0 92~10~26 ~ 2 - 2 ~ 9 7 9 ~ 9 FigurQ Z is a perspeetiYe view of the injeetor o~ Flgure l and a bac~pack used to carried ~e~icament and propellant.
DETAILED DESCRIPTION OF THE DRAhlIN~
As shown ln f1gure l, a nee~leless 3et injector lO0 eomprises a noz~le l through which a high pressured je~ is discharged. Puring the delivery stroke of a delivery piston 31 a check val~e 2 opens, allowlng medicat~on to pass through the nozzle l. The check valve 2 closes on the intake stroke o~ the plston 3 to prevent air from being drawn lnto the interchangeable medieatlon cylinder 22. As the piston 3 re~iprocates, medicat~on is al~ernately drawn into the ~ylin~er 22 ~nd ~lscharged thro4gh the nozzle l.
A me~icatton transfer tube ~ enables medication to be ~ansferred from a medl~ation receiver 6 to the med~cation cylinder 22. A check valve 5 clo~es on the dQlivery s~roke o~ the piston 3 preYQnting medication from passing back into ~he re~eiver 6. The eheck valve 5 opens on the ~ntake s~ro~e of ~he piston to allow medication to flow ~rom the recetv0r 6 to the cYlinder 22. The medleat~on receiver 6 is a ~hamb~r ~thln the body o~ the injeCtor which receives and holds medlcation fro~ an external soUrce such as a baekpack.
2~ To ensu~e that the rear port10n o~ the cyllnd~r ~ln ~hlch the piston rod 8 resl~es~ is open ~o atmospher~c pressure during b~h intaka and dell~ery stro~e~, a cylinder ven~ 7 ts provided throu~h the rear of the mQdlcatlon cylin~er.
The piston rod ~ connec~s the delivery piston 3 to a ~2 pis~on 9. When a pressurlzed ~as such as C02 i~ released from ~he C2 receiv~ng chamber 13 it passes through ~ ~2 release valve 14 (if open) and tnto a C0z chamber 24. ~ collar st~p lO i5 provided ~n the ch~mber 24 ~or limiting and ad~sting the retu~n stop position of the p~ston 9. A ~orm and rack ~echanism ll respond~ to rotation o~ the 30 st~oke adiust~r 12, movlng the stop lO ~orward and backward in a linea~
~shion thereby altering the stroke o~ ~he plstQn 9.
The C02 release v~1ve 14 is opene~ by aetuation o~ ~he tr~er and l~ver mechanism 20 actlng through ~he release valve actuator 15, Opening the C02 rel~ase valYe 14 allows pressurized g~s to travel from ~5 ~hQ recelvlng ~hamber 13, lnt~ t~e delivery cha~ber 24 and hence lnto the working portion of th~ cylinder 23 ~or the p~rpose or displacing the plston 9.

g 1 1.610 N ~ I.q ~ n~ Nl~r~ n.ll ~fifi~ un~ l.

~o 92/~02~fi _ 3 _ 2 ~ ~ 7 9 ~ 9 PcrfA~9l/005~

A r~lease \lalve ac~ua~4r 15 is provide~ which~ upon upward deflection of the trig~er and le~er ~echanism 20, opens the C02 release valve 14 an~ closes the C02 cylinder vent Yalve 16. ~ith the trigger an~ lever mechanism Z0 Stlll held in the upward deflected posltionl the rele~se valve actuator lS allows the release valve 14 to ~lose, stopplng the ~low o~ pressurized g~s lnto the delive~y ¢hamber 24 at the completlon of ~he delivery st~oke.
The cyl~nde~ vent valve 16 ap~ns upon the rel~ase of the ~r~gger and l?ver ~echanism ~0 and allows the cylinder Z3 ~o be vented to the 10 atmosphere via the cy1inder port 17, lever por~ 18 ~nd handle vent 19.
At the completion o~ the delivery stroke, a t~nsfer valve 21 opens and allows pressvrized gas to fill the return chambe~ 2~. Upon release o~ the tr~gger end lever mechanism 20 the cylinder ~ent ~ e ~6 opens and the cyllnder 23 is vented ~o atmosphere ~hlch ln turn allows the 1~ pressu~lzed g~s in ~he return chamber 25 to drive the piston 9 back to the collar stoP 10. With th~ return ~ravel o~ the plston 9, the piston 3 ~raws medication into the ~edicatian cyllnder 22.
As sho~n in ~ig~re 2, a trlgger operated jet injec hr ne~teless syrtn~e 100 according to the teach~ngs o~ the present inventi~n may be ~se~ ln con~U~ct~on with a ba~kp~ck harness 101. The harness 101 m~y be used to support a medi~amen~ cytlnder 102 and a liquid carbon dioxide cy71nder 103. The Con~ents of the medicament and C02 cylin~ers ~re discharge~ through a manl~old 104 and through separate hoses 1~, 105 to the respect~ve intake ports of the injector 100.
Z5 The backpack harness may consist of a ri~id mount~n~ frame which includes wa~st and shoulder straps whieh can be ad~usted to the wearer~s needs. The C02 and medtcament ~anifold(s~ may either be attached to the harness or separately attached to Qach of the cyllnders.
The pressur ked gas cylinder, preferably a carbondlo~lde cyl~nder, will 4e ~ high pressure c~linder containing approximately Z.5 kilo~rams of llquid car~on dioxide which is used as ~he pressu~e medium for ~tuatin~ th~ plston 9.
The ~edicament ~yllnder may be an unpr~ssurized vessel of 1ight hei~h~ material to contain ~he particular medicament use~ in a partic~lar 35 lnoculation program~ Like ~he pressurized gas cylinder lt ls readily ~eplacable and refillable.

1. ~ n ON q~C 1 ~7 7 l a Mf\Cn~TIT~ :~ AlrlCn~TrTC I n ' l T ~ n ,~ I

WO ~/10226 4 P~T~AII~1/005~6 - 2~7c~
Both the medicament cylinder 2~ and no~zle 1 of the iniecror 100 are replacable. The ~ylinder may be tailored to suit the cor~eCt ~age o~ a particular medtcament. The noz~le contains a very fine bore whleh, on release o~ the pts~on 4nder the gas p~essure, wi~l create a high p~essure, high veloçlty ~et. The nat~re o~ the high veloci~y iet throush the fine bore creates ~ear within the bore and after a perl~d of time, thls wear ~ e~uce the efficiency of p~netration o~ the medicamen~.
The nozzle is ~he~e~ore readily replacable in the fiel~ at the first slgn of r~du~ed ef~iciency which will be not~iç~ble by wetting of the skin surface.
The ~njector portion 100 may b~ provlded in two or more sizes utllising the same operating principles. A larger robust unit ts par~te~larly su~ted to mass inoculation o~ sheepl cattl2, pi~s an~ other animals, A s~aller ~nit is more suitable for the mass inoculation o~
~hlldren and adults.
A ~a~or benefit of this invention ls the fully auto~atlc reloading ~nd recha~ging for rapi~ multlpte injections. The unlt ls ~u11y ad~ustable ln ~oth dosage and charge for diffQ~nce thickness s~lns and ~lfferent stzes o~ antmals. ~ecause it is a needleless syringe, tt completely elimtnates ~he problem of cross contam~natlon or infectton ~hich exlsts w~h mass inoculation ~ith multiple u~e n~edles, ~ hlle the present ln~ention has been des~ribe~ w~h re~erenee to parttc~lar mechantc~t ~o~ponents and detatls o~ ¢onstruction, these should ~e understoo~ as having been provided by ~ay of example an~ not as limt~atjon to the scope of the invention.

8 d l610 N 98~ ( % 1~ Nr)~n~ Nrl~n~i~ 2h l.~ 1 un~ 1

Claims (14)

1. A needleless jet injector device for use with a supply of gas under pressure and medicament, the device comprising a body having a gas inlet for said gas and a medicament inlet for said medicament, a first chamber communicating with said medicament inlet and having an outlet, a jet nozzle communicating with said outlet so as to receive medicament, under pressure, for injection, a second chamber communicating with said gas inlet, a first piston at least partly defining said first chamber and movable to vary the volume thereof so as to deliver a dose of medicament under pressure to said outlet, a second piston at least partly defining said second chamber and movable to vary the volume thereof, connection means coupling the first and second pistons so that movement of said second piston causes movement of said first piston, medicament flow control means to operatively restrict flow of the medicament from the medicament inlet to said first chamber, and control means to regulate the flow of gas to said second chamber to cause movement of said second piston and therefor movement of said first piston.
2. A needleless jet injector device according to claim 1, wherein the medicament flow control means comprises a one way valve between the first chamber and the nozzle to allow medicament to pass out from the first chamber through the nozzle but to prevent air being drawn back into the first chamber.
3. A needleless jet injector device according to either claim l or claim 2, wherein said body is provide with a medicament storage chamber coupled to receive medicament from the medicament inlet and an outlet connected to the first chamber.
4. A needleless jet injector device according to claim 3, further comprising a one way valve between the first chamber and the medicament storage chamber to allow medicament to pass from the medicament storage chamber to the first chamber but to prevent passage back into the medicament storage chamber.
5. A needleless jet injector device according to any preceding claim, wherein said body is provided with a gas storage chamber coupled to receive gas from the gas inlet and an outlet connected to the second chamber.
6. A needleless jet injector device according to claim 5, wherein said control means comprises a release valve between the second chamber and the gas storage chamber to allow gas to pass from the gas storage chamber of the second chamber.
7. A needleless jet injector device according to claim 6, further comprising a trigger means for releasing the release valve upon actuation of the trigger means.
8. A needleless jet injector device according to any preceding claim, wherein the connection means is movable in a cylinder, the cylinder being provided with a vent to atmosphere.
9. A needleless jet injector device according to any preceding claim, further comprising means for adjusting the amount of travel of the first and second pistons so as to thereby adjust the amount of medicament discharged through the nozzle.
10. A needleless jet injector device according to claim 9, wherein said means for adjusting comprises a movable collar arranged within the second chamber against which collar the second piston abuts when at a rearmost position of its stroke.
11. A needleless jet injector device according to claim 10, wherein the collar is movable forwards and rearwards by means of a worm screw arrangement to thereby move the first piston within the first chamber to decrease or increase the volume of the first chamber and hence the amount of medicament therein.
12. A combination of a needleless jet injector device according to any preceding claim and a backpack containing a gas storage tank and a medicament storage tank connected to the gas inlet and the medicament inlet, respectively.
13. A combination according to claim 12, further comprising a manifold between the gas storage tank and the gas inlet and the medicament storage tank and the medicament inlet.
14. A combination according to either claim 12 or claim 13, wherein the backpack is provided with a frame and straps for mounting the backpack on a user.
CA002097919A 1990-12-07 1991-12-06 Jet injector for mass inoculation Abandoned CA2097919A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPK3801 1990-12-07
AUPK380190 1990-12-07

Publications (1)

Publication Number Publication Date
CA2097919A1 true CA2097919A1 (en) 1992-06-08

Family

ID=3775128

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002097919A Abandoned CA2097919A1 (en) 1990-12-07 1991-12-06 Jet injector for mass inoculation

Country Status (3)

Country Link
EP (1) EP0560856A4 (en)
CA (1) CA2097919A1 (en)
WO (1) WO1992010226A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8221347B2 (en) 2004-12-01 2012-07-17 Acushot, Inc. Needle-free injector

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5569190A (en) * 1987-06-08 1996-10-29 D'antonio; Nicholas F. Hypodermic fluid dispenser
ES2169380T3 (en) * 1996-09-20 2002-07-01 Novo Nordisk As OPERATING CYLINDER
DE19820172A1 (en) * 1997-09-30 2005-01-27 Wolfgang Wagner Injection arrangement for inserting a diagnostic carrier or medicament beneath a patient's skin has a compressed gas source and a valve closure for controlling the release of the gas that is used to inject a substance
DE10116778A1 (en) * 2001-04-04 2002-10-17 Roesch Ag Medizintechnik injection device
JP4546728B2 (en) * 2001-10-12 2010-09-15 フェルトン・インターナショナル・インコーポレーテッド Jet injector with handpiece
DE10158118C2 (en) * 2001-11-27 2003-11-20 Zeller & Gmelin Gmbh & Co Use of a coating composition to produce a protective layer on plastic surfaces

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3057349A (en) * 1959-12-14 1962-10-09 Ismach Aaron Multi-dose jet injection device
US3406684A (en) * 1964-09-28 1968-10-22 Yuryo Kikakuhin Kenkyusho Kk Jet type, medical injection instrument
US3561443A (en) * 1968-09-06 1971-02-09 Oscar H Banker Inoculator gun with delayed action
JPS51130094A (en) * 1975-05-08 1976-11-12 Asahi Chemical Ind Twoostage pressure injector
BR7704105A (en) * 1977-03-07 1978-09-26 Vernitron Corp HYPODERMIC JET INJECTION DEVICE
US4421508A (en) * 1981-02-24 1983-12-20 Cohen Edgar C Vacuum-compression injector
DE3115376A1 (en) * 1981-04-16 1982-12-16 Hoechst Ag, 6000 Frankfurt NEEDLE-FREE INJECTION DEVICE
DE3115377A1 (en) * 1981-04-16 1982-12-16 Hoechst Ag, 6000 Frankfurt NEEDLE-FREE INJECTION DEVICE
JPH0622637B2 (en) * 1987-05-26 1994-03-30 アカリス,クロード Needleless liquid injection device especially for dental treatment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8221347B2 (en) 2004-12-01 2012-07-17 Acushot, Inc. Needle-free injector

Also Published As

Publication number Publication date
EP0560856A4 (en) 1994-06-01
EP0560856A1 (en) 1993-09-22
WO1992010226A1 (en) 1992-06-25

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