CA2089239A1 - Novel branched cyclodextrins and methods of preparing them - Google Patents

Novel branched cyclodextrins and methods of preparing them

Info

Publication number
CA2089239A1
CA2089239A1 CA002089239A CA2089239A CA2089239A1 CA 2089239 A1 CA2089239 A1 CA 2089239A1 CA 002089239 A CA002089239 A CA 002089239A CA 2089239 A CA2089239 A CA 2089239A CA 2089239 A1 CA2089239 A1 CA 2089239A1
Authority
CA
Canada
Prior art keywords
cyclodextrin
galactosyl
group
novel
bond
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002089239A
Other languages
French (fr)
Other versions
CA2089239C (en
Inventor
Sumio Kitahata
Koji Hara
Koki Fujita
Nobuhiro Kuwahara
Kyoko Koizumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ensuiko Sugar Refining Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002513617A priority Critical patent/CA2513617C/en
Publication of CA2089239A1 publication Critical patent/CA2089239A1/en
Application granted granted Critical
Publication of CA2089239C publication Critical patent/CA2089239C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/738Cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Disclosed are (1) a novel galactosyl-cyclodextrin having a galactosyl group bonded to a hydroxyl group of a glucosyl group of a cyclodextrin via an .alpha. -bond and a method of producing the galactosyl-cyclodextrin; (2) a novel galactosyl-cyclodextrin having a galactosyl group bonded to a hydroxyl group of a glucosyl group of a cyclodextrin via a .beta. -bond and a method of producing the galactosyl-cyclodextrin ; and (3) a novel mannosyl-cyclodextrin having a mannosyl group bonded to a hydroxyl group of a glucosyl group of a cyclodextrin via an .alpha. -bond and a method of producing the mannosyl-cyclodextrin. The new branched cyclodextrins are expected to be widely useful in various fields of drug industry, food industry and cosmetic industry.
CA002089239A 1992-04-08 1993-02-10 Novel branched cyclodextrins and methods of preparing them Expired - Fee Related CA2089239C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002513617A CA2513617C (en) 1992-04-08 1993-02-10 Branched cyclodextrins and methods of preparing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP04114304A JP3078923B2 (en) 1992-04-08 1992-04-08 Novel branched cyclodextrin and method for producing the same
JP114304/1992 1992-04-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002513617A Division CA2513617C (en) 1992-04-08 1993-02-10 Branched cyclodextrins and methods of preparing them

Publications (2)

Publication Number Publication Date
CA2089239A1 true CA2089239A1 (en) 1993-10-09
CA2089239C CA2089239C (en) 2006-04-18

Family

ID=14634526

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002513617A Expired - Fee Related CA2513617C (en) 1992-04-08 1993-02-10 Branched cyclodextrins and methods of preparing them
CA002089239A Expired - Fee Related CA2089239C (en) 1992-04-08 1993-02-10 Novel branched cyclodextrins and methods of preparing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002513617A Expired - Fee Related CA2513617C (en) 1992-04-08 1993-02-10 Branched cyclodextrins and methods of preparing them

Country Status (6)

Country Link
US (3) US5523218A (en)
EP (2) EP0565105B1 (en)
JP (1) JP3078923B2 (en)
CA (2) CA2513617C (en)
DE (2) DE69315734T2 (en)
DK (1) DK0565105T3 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4325057C2 (en) * 1993-07-26 1996-10-17 Consortium Elektrochem Ind Process for the preparation of branched cyclodextrins
JP3865436B2 (en) * 1996-07-11 2007-01-10 塩水港精糖株式会社 Process for producing branched cyclodextrins
JP4164367B2 (en) 2001-03-09 2008-10-15 株式会社林原生物化学研究所 Branched cyclic tetrasaccharide, production method and use thereof
FR2839313B1 (en) * 2002-05-03 2006-04-07 Chelator NOVEL CYCLODEXTRIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS
WO2006012536A2 (en) 2004-07-22 2006-02-02 Ritter Andrew J Methods and compositions for treating lactose intolerance
US20070021380A1 (en) * 2005-07-22 2007-01-25 Leonard Wiebe Novel drug delivery compositions
US20110223248A1 (en) * 2007-12-12 2011-09-15 Ritter Pharmaceuticals, Inc. Methods and compositions for treating lactose intolerance
SG2014014435A (en) 2009-02-24 2014-07-30 Ritter Pharmaceuticals Inc Prebiotic formulations and methods of use
WO2011137249A1 (en) 2010-04-28 2011-11-03 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
CN108003198B (en) * 2017-11-15 2021-06-18 昆明理工大学 D-galactose-bonded ring-opening cucurbituril and application thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6192592A (en) * 1984-10-12 1986-05-10 Norin Suisansyo Shokuhin Sogo Kenkyusho Production of branched cyclodextrin
JPS6346201A (en) * 1986-08-13 1988-02-27 Natl Food Res Inst Multiply branched cyclodextrin and its production
JPS6474997A (en) * 1987-09-17 1989-03-20 Nat Food Res Complex branched cyclodextrin and production thereof
JPH0698012B2 (en) * 1988-05-13 1994-12-07 農林水産省食品総合研究所長 Manufacturing method of multi-branched glucosyl-cyclodextrin
JP2775046B2 (en) * 1989-12-21 1998-07-09 農林水産省食品総合研究所長 Method for producing modified cyclodextrin containing heterosaccharide
JP2863262B2 (en) * 1990-05-18 1999-03-03 塩水港精糖株式会社 Novel hetero-branched cyclodextrin in which a galactosyl group is transfer-bonded to the side chain portion of a branched cyclodextrin by an α-bond, and a method for producing the same
JP2863263B2 (en) * 1990-05-18 1999-03-03 塩水港精糖株式会社 Novel hetero-branched cyclodextrin in which a galactosyl group is transfer-linked to the side chain part of a branched cyclodextrin by β-bond, and method for producing the same
JPH0543603A (en) * 1991-08-20 1993-02-23 Rikagaku Kenkyusho (galactopyranosyl)cyclomaltheptaose, preparation thereof, and intermediate therefor
JP3122203B2 (en) * 1991-11-13 2001-01-09 塩水港精糖株式会社 Novel heterobranched cyclodextrin and method for producing the same
JPH0614789A (en) * 1992-04-08 1994-01-25 Ensuiko Sugar Refining Co Ltd Production of branched cyclodextrin

Also Published As

Publication number Publication date
CA2513617A1 (en) 1993-10-09
DE69315734D1 (en) 1998-01-29
EP0786524B1 (en) 2000-07-26
CA2089239C (en) 2006-04-18
EP0565105A2 (en) 1993-10-13
DE69329122T2 (en) 2001-03-22
CA2513617C (en) 2006-10-10
EP0565105B1 (en) 1997-12-17
DE69315734T2 (en) 1998-07-09
JPH0616705A (en) 1994-01-25
DE69329122D1 (en) 2000-08-31
DK0565105T3 (en) 1998-04-06
EP0565105A3 (en) 1994-07-06
US5623071A (en) 1997-04-22
US5523218A (en) 1996-06-04
JP3078923B2 (en) 2000-08-21
EP0786524A3 (en) 1997-08-13
EP0786524A2 (en) 1997-07-30
US5622844A (en) 1997-04-22

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Legal Events

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