CA2086101A1 - Immune suppressive product from milk - Google Patents

Immune suppressive product from milk

Info

Publication number
CA2086101A1
CA2086101A1 CA002086101A CA2086101A CA2086101A1 CA 2086101 A1 CA2086101 A1 CA 2086101A1 CA 002086101 A CA002086101 A CA 002086101A CA 2086101 A CA2086101 A CA 2086101A CA 2086101 A1 CA2086101 A1 CA 2086101A1
Authority
CA
Canada
Prior art keywords
milk
allergens
immune suppressive
intact
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002086101A
Other languages
French (fr)
Other versions
CA2086101C (en
Inventor
Lee R. Beck
Ralph J. Stolle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stolle Milk Biologics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2086101A1 publication Critical patent/CA2086101A1/en
Application granted granted Critical
Publication of CA2086101C publication Critical patent/CA2086101C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2/00Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

An immune suppressive product prepared by injecting an allergen or a mixture of allergens into the body of milk-produ-cing species. Said product being the milk or a polypeptide subfraction of milk obtained from the allergen treated host. The im-mune suppressive product(s) is milk and/or the polypeptide fractions contained therein, which is ostensively free of the intact al-lergen or allergens used for the treatment of the host. The immune suppressive factors) being a subtraction of the allergen used for the treatment. A method of preparing immune suppressive polypeptides from intact allergens, which involves injection of the specific intact allergens into a milk-producing species, collecting the immune suppressive polypeptide fractions of the intact al-lergens from the milk of the treated host. The immune suppressive milk containing said polypeptide fractions, and/or the poly-peptide fractions obtained from said milk, are non reactive in animals and humans as allergens. Said factor(s), however, are high-ly effective in preventing or alleviating allergic reactions.
CA002086101A 1990-07-05 1991-04-26 Immune suppressive product from milk Expired - Fee Related CA2086101C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US548,419 1983-11-03
US54841990A 1990-07-05 1990-07-05
PCT/US1991/002923 WO1992000756A1 (en) 1990-07-05 1991-04-26 Immune suppressive product

Publications (2)

Publication Number Publication Date
CA2086101A1 true CA2086101A1 (en) 1992-01-06
CA2086101C CA2086101C (en) 2002-11-19

Family

ID=24188777

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002086101A Expired - Fee Related CA2086101C (en) 1990-07-05 1991-04-26 Immune suppressive product from milk

Country Status (6)

Country Link
EP (1) EP0646017A1 (en)
JP (1) JP3054194B2 (en)
AU (1) AU648800B2 (en)
CA (1) CA2086101C (en)
NZ (2) NZ238117A (en)
WO (1) WO1992000756A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP494798A0 (en) 1998-07-29 1998-08-20 Pacific Biolink Pty Limited Protective protein formulation
GB0002386D0 (en) * 2000-02-02 2000-03-22 Novartis Nutrition Ag Therapeutic composition
US7060687B2 (en) 2001-02-07 2006-06-13 Genmont Biotechnology Co. Live vaccines for allergy treatment
US20020197268A1 (en) * 2001-06-08 2002-12-26 Hsu Ching-Hsaing Allergen-containing milk for allergy treatment
US6770280B1 (en) 2001-11-15 2004-08-03 Humanetics Corporation Treatment of menorrhagia, hypermenorrhea, dysmenorrhea and menstrual migraines by the administration of an antibacterial milk product
US20100129377A1 (en) * 2007-04-16 2010-05-27 Friesland Brands B.V. Milk derived antigen-specific antibodies, methods of preparation and uses thereof
NL1033696C2 (en) * 2007-04-16 2008-10-20 Friesland Brands Bv Obtaining an antigen specific antibody from milk derived from a non-human mammal that has not been immunized with the antigen prior to collecting the milk for delivering an antibody of a ruminant

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3128230A (en) * 1961-04-04 1964-04-07 Sunbury Milk Products Co Milk having antibodies therein and process for producing same
US3376198A (en) * 1965-07-21 1968-04-02 Collins Products Inc Method of producing antibodies in milk
US4732757A (en) * 1978-02-06 1988-03-22 Stolle Research And Development Corporation Prevention and treatment of rheumatoid arthritis
US4284623A (en) * 1979-11-09 1981-08-18 Beck Lee R Method of treating inflammation using bovine milk
USRE33403E (en) * 1982-06-03 1990-10-23 Stolle Research & Development Corporation Method for treating disorders of the vascular and pulmonary systems
US4879110A (en) * 1983-10-27 1989-11-07 Stolle Research And Development Corporation Antihypertensive hyperimmune milk, production, composition, and use
US4636384A (en) * 1982-06-03 1987-01-13 Stolle Research & Development Corporation Method for treating disorders of the vascular and pulmonary systems
US5242691A (en) * 1982-06-03 1993-09-07 Stolle Research & Development Corporation Anti-inflammatory factor, method of isolation, and use
US4956349A (en) * 1983-10-27 1990-09-11 Stolle Research & Development Corporation Anti-inflammatory factor, method of isolation, and use
AU590711B2 (en) * 1982-10-13 1989-11-16 Biowhittaker, Inc. Stable allergenic extracts and methods

Also Published As

Publication number Publication date
AU648800B2 (en) 1994-05-05
JP3054194B2 (en) 2000-06-19
AU7891691A (en) 1992-02-04
NZ238117A (en) 1996-01-26
CA2086101C (en) 2002-11-19
JPH05508397A (en) 1993-11-25
NZ505179A (en) 2002-06-28
WO1992000756A1 (en) 1992-01-23
EP0646017A1 (en) 1995-04-05
EP0646017A4 (en) 1993-07-12

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed