CA2084677A1 - Apo ai polypeptides, antibodies, and immunoassays - Google Patents
Apo ai polypeptides, antibodies, and immunoassaysInfo
- Publication number
- CA2084677A1 CA2084677A1 CA002084677A CA2084677A CA2084677A1 CA 2084677 A1 CA2084677 A1 CA 2084677A1 CA 002084677 A CA002084677 A CA 002084677A CA 2084677 A CA2084677 A CA 2084677A CA 2084677 A1 CA2084677 A1 CA 2084677A1
- Authority
- CA
- Canada
- Prior art keywords
- apo
- antibodies
- polypeptide
- immunoassays
- polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
The present invention describes an Apo AI polypeptide capable of immunologically mimicking an Apo AI epitope. The polypeptide is useful in diagnostic methods and systems for detecting Apo AI
in vascular fluid samples, and for preparation of anti-Apo AI antibodies. In addition, the polypeptide is useful in therapeutic methods for increasing esterified cholesterol in a hu-man patient.
in vascular fluid samples, and for preparation of anti-Apo AI antibodies. In addition, the polypeptide is useful in therapeutic methods for increasing esterified cholesterol in a hu-man patient.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53476190A | 1990-06-07 | 1990-06-07 | |
US534,761 | 1990-06-07 | ||
PCT/US1991/004038 WO1991018619A1 (en) | 1990-06-07 | 1991-06-07 | Apo ai polypeptides, antibodies, and immunoassays |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2084677A1 true CA2084677A1 (en) | 1991-12-08 |
CA2084677C CA2084677C (en) | 2003-11-04 |
Family
ID=24131429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002084677A Expired - Fee Related CA2084677C (en) | 1990-06-07 | 1991-06-07 | Apo ai polypeptides, antibodies, and immunoassays |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0500826A4 (en) |
JP (1) | JPH06508344A (en) |
CA (1) | CA2084677C (en) |
IE (1) | IE911922A1 (en) |
PT (1) | PT97914B (en) |
WO (1) | WO1991018619A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7125678B2 (en) * | 2001-11-23 | 2006-10-24 | Nanogen, Inc. | Protein biopolymer markers predictive of type II diabetes |
US8138313B2 (en) | 2007-06-15 | 2012-03-20 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Treatment of tumors using specific anti-L1 antibody |
NO335243B1 (en) | 2008-01-08 | 2014-10-27 | Isola As | Cradle plate, as well as the application and method of laying a floor covering using such a cradle plate. |
EP3604517A4 (en) * | 2017-03-30 | 2020-12-16 | Sysmex Corporation | Anti-apoa1 antibody |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5055396A (en) * | 1987-11-03 | 1991-10-08 | Scripps Clinic And Research Foundation | Diagnostic methods and systems for quantifying apo ai |
KR900700884A (en) * | 1988-03-29 | 1990-08-17 | 레이먼드 에이치. 칸 | Diagnostic Methods and Diagnostic Systems for Quantifying Apo AI |
-
1991
- 1991-06-05 IE IE192291A patent/IE911922A1/en not_active IP Right Cessation
- 1991-06-07 PT PT97914A patent/PT97914B/en not_active IP Right Cessation
- 1991-06-07 WO PCT/US1991/004038 patent/WO1991018619A1/en not_active Application Discontinuation
- 1991-06-07 EP EP19910912441 patent/EP0500826A4/en not_active Ceased
- 1991-06-07 CA CA002084677A patent/CA2084677C/en not_active Expired - Fee Related
- 1991-06-07 JP JP3511924A patent/JPH06508344A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
IE911922A1 (en) | 1991-12-18 |
CA2084677C (en) | 2003-11-04 |
PT97914B (en) | 1998-11-30 |
JPH06508344A (en) | 1994-09-22 |
PT97914A (en) | 1992-03-31 |
EP0500826A4 (en) | 1993-06-30 |
EP0500826A1 (en) | 1992-09-02 |
WO1991018619A1 (en) | 1991-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |