CA2080019A1 - Methode et composition pour les dosages de l'adn - Google Patents

Methode et composition pour les dosages de l'adn

Info

Publication number
CA2080019A1
CA2080019A1 CA 2080019 CA2080019A CA2080019A1 CA 2080019 A1 CA2080019 A1 CA 2080019A1 CA 2080019 CA2080019 CA 2080019 CA 2080019 A CA2080019 A CA 2080019A CA 2080019 A1 CA2080019 A1 CA 2080019A1
Authority
CA
Canada
Prior art keywords
nucleic acid
test tubes
magnetically responsive
solution
pipetter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2080019
Other languages
English (en)
Inventor
Edward G. Jablonski
Rolf Lohrmann
Jerry L. Ruth
Eugene Tu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngene Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2080019A1 publication Critical patent/CA2080019A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
CA 2080019 1990-04-06 1991-04-03 Methode et composition pour les dosages de l'adn Abandoned CA2080019A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50590490A 1990-04-06 1990-04-06
US505,904 1990-04-06

Publications (1)

Publication Number Publication Date
CA2080019A1 true CA2080019A1 (fr) 1991-10-07

Family

ID=24012368

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2080019 Abandoned CA2080019A1 (fr) 1990-04-06 1991-04-03 Methode et composition pour les dosages de l'adn

Country Status (5)

Country Link
EP (1) EP0523171A1 (fr)
JP (1) JPH05507613A (fr)
AU (1) AU7575291A (fr)
CA (1) CA2080019A1 (fr)
WO (1) WO1991015768A1 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1245286B1 (fr) * 1993-10-22 2009-11-25 Abbott Laboratories Tube de réaction et méthode d'utilisation de celui-ci minimisant les contaminations
US5871918A (en) * 1996-06-20 1999-02-16 The University Of North Carolina At Chapel Hill Electrochemical detection of nucleic acid hybridization
US6919175B1 (en) 1995-04-01 2005-07-19 Roche Diagnostics Gmbh System for releasing and isolating nucleic acids
DE19512368A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh System zur Freisetzung und Isolierung von Nukleinsäuren
US6387625B1 (en) 1995-06-27 2002-05-14 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US6127127A (en) * 1995-06-27 2000-10-03 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US6346387B1 (en) 1995-06-27 2002-02-12 Xanthon, Inc. Detection of binding reactions using labels detected by mediated catalytic electrochemistry
US5968745A (en) * 1995-06-27 1999-10-19 The University Of North Carolina At Chapel Hill Polymer-electrodes for detecting nucleic acid hybridization and method of use thereof
US6180346B1 (en) 1995-06-27 2001-01-30 The Universtiy Of North Carolina At Chapel Hill Electropolymerizable film, and method of making and use thereof
US6132971A (en) * 1995-06-27 2000-10-17 The University Of North Carolina At Chapel Hill Microelectronic device
JP2000501601A (ja) * 1995-06-27 2000-02-15 ザ ユニヴァーシティ オブ ノース カロライナ アット チャペル ヒル 核酸ハイブリッド形成の電気化学的検出
US6361951B1 (en) 1995-06-27 2002-03-26 The University Of North Carolina At Chapel Hill Electrochemical detection of nucleic acid hybridization
DE19819447A1 (de) 1998-04-30 1999-11-04 Roche Diagnostics Gmbh Vorrichtung und Verfahren zum Mischen und Waschen von Flüssigkeiten und/oder Feststoffen
DE1075328T1 (de) 1998-05-01 2001-10-11 Ammann Kelly G Automatische diagnostische analysevorrichtung und -verfahren
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
US7202028B2 (en) 2001-09-24 2007-04-10 The University Of North Carolina At Chapel Hill Methods for the electrochemical detection of multiple target compounds
CA2842232C (fr) 2005-03-10 2015-01-27 Gen-Probe Incorporated Systemes et procedes permettant d'effectuer des dosages afin de detecter ou de quantifier des analytes dans des echantillons
EP1947463A1 (fr) * 2007-01-16 2008-07-23 Roche Diagnostics GmbH Collecte d'échantillons analytiques liquides à des fins d'analyses cliniques
DE102007004925B3 (de) * 2007-02-01 2008-04-03 Christian-Albrechts-Universität Zu Kiel Mischbehälter und Mischvorrichtung
EP2110670A4 (fr) * 2007-02-07 2013-03-06 Universal Bio Research Co Ltd Appareil de traitement parallèle de particule magnétique permettant une utilisation répétée d'un conteneur et procédé de traitement parallèle de particule magnétique permettant une utilisation répétée du conteneur
CN103540518B (zh) 2010-07-23 2015-07-08 贝克曼考尔特公司 化验盒
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
CN103403533B (zh) 2011-02-24 2017-02-15 简.探针公司 用于分辨光信号检测器中不同调制频率的光信号的系统和方法
WO2013070740A1 (fr) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Système d'aliquote et flux de travail
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
BR112014011046A2 (pt) 2011-11-07 2017-06-13 Beckman Coulter, Inc. fluxo de trabalho e sistema de centrífuga
WO2013070754A1 (fr) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Bras robotique
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
CN104053997B (zh) 2011-11-07 2016-12-21 贝克曼考尔特公司 用于处理样本的系统和方法
DE102013200193A1 (de) 2013-01-09 2014-07-10 Hamilton Bonaduz Ag Probenverarbeitungssystem mit Dosiervorrichtung und Thermocycler

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861705A (en) * 1983-01-31 1989-08-29 Yeda Research And Development Company, Ltd. Method for removing components of biological fluids
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
GB8507706D0 (en) * 1985-03-25 1985-05-01 Genetics Int Inc Magnetic nucleic acid sequences
CH669851A5 (fr) * 1986-03-06 1989-04-14 Tecan Ag
AU8173387A (en) * 1986-10-10 1988-05-06 Peter Grandics A novel immunoaffinity purification system
DE3852299T2 (de) * 1987-10-26 1995-07-20 Baxter Diagnostics Inc Verfahren zur herstellung magnetisch empfindlicher polymerteilchen und deren anwendung.
AU2735988A (en) * 1987-12-21 1989-07-13 Amoco Corporation Target and background capture methods with amplification for affinity assays
NO165894C (no) * 1988-05-24 1991-04-24 Gunnar Paulsen Analysemetode for gener.
US5147529A (en) * 1988-08-10 1992-09-15 E. I. Du Pont De Nemours And Company Method for automatically processing magnetic solid phase reagents
EP0446260B1 (fr) * 1988-11-21 1994-03-02 Dynal A.S. Sondes d'acide nucleique

Also Published As

Publication number Publication date
JPH05507613A (ja) 1993-11-04
WO1991015768A1 (fr) 1991-10-17
EP0523171A1 (fr) 1993-01-20
AU7575291A (en) 1991-10-30

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