CA2071205A1 - Cell Surface Antigen Associated with Cellular Apoptosis - Google Patents

Cell Surface Antigen Associated with Cellular Apoptosis

Info

Publication number
CA2071205A1
CA2071205A1 CA2071205A CA2071205A CA2071205A1 CA 2071205 A1 CA2071205 A1 CA 2071205A1 CA 2071205 A CA2071205 A CA 2071205A CA 2071205 A CA2071205 A CA 2071205A CA 2071205 A1 CA2071205 A1 CA 2071205A1
Authority
CA
Canada
Prior art keywords
cell surface
surface antigen
antigen associated
cellular apoptosis
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2071205A
Other languages
French (fr)
Other versions
CA2071205C (en
Inventor
Peter H. Krammer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP90901787A priority Critical patent/EP0511202B1/en
Priority to DE69009497T priority patent/DE69009497T2/en
Priority to PCT/EP1990/000111 priority patent/WO1991010448A1/en
Priority claimed from PCT/EP1990/000111 external-priority patent/WO1991010448A1/en
Publication of CA2071205A1 publication Critical patent/CA2071205A1/en
Application granted granted Critical
Publication of CA2071205C publication Critical patent/CA2071205C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Dry Development In Electrophotography (AREA)

Abstract

A 52kD antigen associated with cellular apoptosis is described. The antigen is expressed by activated and malignant lymphoid cells. Antibodies which bind the antigen induce growth inhibition and apoptosis.
CA002071205A 1990-01-19 1990-01-19 Cell surface antigen associated with cellular apoptosis Expired - Fee Related CA2071205C (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP90901787A EP0511202B1 (en) 1990-01-19 1990-01-19 A cell surface antigen associated with cellular apoptosis
DE69009497T DE69009497T2 (en) 1990-01-19 1990-01-19 CELL SURFACE ANTIQUE ASSOCIATED WITH CELLULAR APOPTOSIS.
PCT/EP1990/000111 WO1991010448A1 (en) 1990-01-19 1990-01-19 A cell surface antigen associated with cellular apoptosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1990/000111 WO1991010448A1 (en) 1990-01-19 1990-01-19 A cell surface antigen associated with cellular apoptosis

Publications (2)

Publication Number Publication Date
CA2071205A1 true CA2071205A1 (en) 1991-07-20
CA2071205C CA2071205C (en) 2000-03-14

Family

ID=8165461

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002071205A Expired - Fee Related CA2071205C (en) 1990-01-19 1990-01-19 Cell surface antigen associated with cellular apoptosis

Country Status (2)

Country Link
JP (1) JP2963535B2 (en)
CA (1) CA2071205C (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020008197A (en) 1999-05-24 2002-01-29 가와무라 요시부미 MEDICINAL COMPOSITIONS CONTAINING ANTI-Fas ANTIBODY

Also Published As

Publication number Publication date
CA2071205C (en) 2000-03-14
JP2963535B2 (en) 1999-10-18
JPH05503281A (en) 1993-06-03

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed