CA2070697A1 - Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof - Google Patents
Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereofInfo
- Publication number
- CA2070697A1 CA2070697A1 CA 2070697 CA2070697A CA2070697A1 CA 2070697 A1 CA2070697 A1 CA 2070697A1 CA 2070697 CA2070697 CA 2070697 CA 2070697 A CA2070697 A CA 2070697A CA 2070697 A1 CA2070697 A1 CA 2070697A1
- Authority
- CA
- Canada
- Prior art keywords
- mortierella
- ifo
- isabellina
- ramanniana
- mortierella isabellina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure:
which includes the stereoisomers having the structures:
by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure:
wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of:
Mortierella isabellina, ATCC 44583;
Mortierella isabellina, ATCC 38063;
Syncephalastrum racemosum, NRRL A-5889;
Mortierella isabellina, IFO 7884;
Mortierella ramanniana var, angulispo_ra, IFO 8187;
Mortierella isabellina, CBS 221,29;
Mortierella isabellina, IFO 7873;
Mortierella ramanniana var. ramanniana, CBS 112.08;
Mortierella ramanniana var. ramanniana, CBS 478.63;
Choanephora cucurbitarum, NRRL 2744;
Mortierella isabellina, TFO 8183;
Mortierella isabellina, IFO 8309;
Mortierella nana, IFO 8794;
Mortierella isabellina, IFO 7824; and Mortierella vinacea, IFO 6738 whereby a gamma hydroxy octanoic acid defined according to the structure:
is formed, and (ii) lactonization of the resulting gamma hydroxy octanoic acid by means of simultaneous acidification and heating according to the reaction sequence:
which includes the stereoisomers having the structures:
by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure:
wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of:
Mortierella isabellina, ATCC 44583;
Mortierella isabellina, ATCC 38063;
Syncephalastrum racemosum, NRRL A-5889;
Mortierella isabellina, IFO 7884;
Mortierella ramanniana var, angulispo_ra, IFO 8187;
Mortierella isabellina, CBS 221,29;
Mortierella isabellina, IFO 7873;
Mortierella ramanniana var. ramanniana, CBS 112.08;
Mortierella ramanniana var. ramanniana, CBS 478.63;
Choanephora cucurbitarum, NRRL 2744;
Mortierella isabellina, TFO 8183;
Mortierella isabellina, IFO 8309;
Mortierella nana, IFO 8794;
Mortierella isabellina, IFO 7824; and Mortierella vinacea, IFO 6738 whereby a gamma hydroxy octanoic acid defined according to the structure:
is formed, and (ii) lactonization of the resulting gamma hydroxy octanoic acid by means of simultaneous acidification and heating according to the reaction sequence:
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/719,154 US5112803A (en) | 1991-06-21 | 1991-06-21 | Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof |
US719,154 | 1991-06-21 | ||
US07/797,055 US5166366A (en) | 1991-06-21 | 1992-01-23 | Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof |
US797,055 | 1992-01-23 | ||
US887,144 | 1992-05-22 | ||
US07/887,144 US5274128A (en) | 1991-06-21 | 1992-05-22 | Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2070697A1 true CA2070697A1 (en) | 1992-12-22 |
CA2070697C CA2070697C (en) | 2001-08-21 |
Family
ID=27418992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2070697 Expired - Fee Related CA2070697C (en) | 1991-06-21 | 1992-06-08 | Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2070697C (en) |
-
1992
- 1992-06-08 CA CA 2070697 patent/CA2070697C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2070697C (en) | 2001-08-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8300353A1 (en) | ML-236B Derivatives and their preparation | |
IE822061L (en) | Mb-530b derivatives | |
KR840002451A (en) | Method for preparing 3-hydroxy-ML-236B derivative | |
EP0743335A3 (en) | Hyperbranched polyaspartate esters and a process for their preparation | |
JPS561889A (en) | Preparation of l-glutamic acid by fermentation | |
CA2079876A1 (en) | Process for preparing mixtures of 2-acylglycerides and 1,2 or 2,3-diacylglycerides | |
DE3370475D1 (en) | Synthesis of acrylic or methacrylic acid esters | |
CA2070697A1 (en) | Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof | |
CA2202016C (en) | Process for the production of lipstatin and of tetrahydrolipstatin | |
KR840003696A (en) | Method for preparing 2-keto-L-gulonic acid | |
EP0269351A3 (en) | Method for producing fat containing gamma-linolenic acid | |
NZ513130A (en) | Vaccine composition containing a monoglyceride adjuvant with inactivated Mycobacterium tuberculosis bacteria | |
ES8308358A1 (en) | ML-236B Derivatives, a process for their preparation and pharmaceutical compositions containing them. | |
KR970027044A (en) | Method for producing (meth) acrylic acid ester | |
MY111010A (en) | Fractionation of triglyceride oils | |
Matsumoto et al. | New antibiotics from Cylindrocarpon sp. | |
KR850003732A (en) | Method for preparing antibiotic A39079 factor S-1 | |
JPS57145896A (en) | Glycolipid and its preparation by fermentation | |
JPH01160478A (en) | Novel candida tropicalis and method for preparing dicarboxylic acid by using it | |
KR840005489A (en) | Process for preparing de (micinosiloxy) tyrosine derivative | |
NAKAHAMA et al. | Microbial conversion of antibiotics. II Deacylation of maridomycin by actinomycetes | |
CA2101945C (en) | Process for producing optically active norborneol | |
JPS5750894A (en) | Preparation of ml-236b derivative | |
JPS6413091A (en) | Novel macrolide compound and production thereof | |
JPS57152898A (en) | Fermentative preparation of androst-1,4-diene-3,17-dione |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |