CA2063872A1 - Pharmaceutical preparation based on plasma proteins - Google Patents

Pharmaceutical preparation based on plasma proteins

Info

Publication number
CA2063872A1
CA2063872A1 CA2063872A CA2063872A CA2063872A1 CA 2063872 A1 CA2063872 A1 CA 2063872A1 CA 2063872 A CA2063872 A CA 2063872A CA 2063872 A CA2063872 A CA 2063872A CA 2063872 A1 CA2063872 A1 CA 2063872A1
Authority
CA
Canada
Prior art keywords
igg
transferrin
iga
weight
plasma proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2063872A
Other languages
French (fr)
Other versions
CA2063872C (en
Inventor
Johann Eibl
Martha Eibl
Yendra Linnau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Johann Eibl
Martha Eibl
Yendra Linnau
Immuno Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johann Eibl, Martha Eibl, Yendra Linnau, Immuno Aktiengesellschaft filed Critical Johann Eibl
Publication of CA2063872A1 publication Critical patent/CA2063872A1/en
Application granted granted Critical
Publication of CA2063872C publication Critical patent/CA2063872C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

There is disclosed a pharmaceutical preparation based on plasma proteins and having antimicrobial, antiphlogistic and antiallergic activities. This preparation contains immunoglobulin A (IgA), immunoglobulin G (IgG) and transferrin, wherein between 0.40 and 0.80 parts by weight of IgG and 0.15 to 0.45 parts by weight of transferrin are provided per part by weight of IgA. It has proved that both the intensity of action on the bacterial and viral pathogens and the spectrum of an IgA- and IgG-containing preparation may be increased if it additionally contains transferrin and the three components IgA, IgG and transferrin are present at the weight ratios defined by the invention.
CA002063872A 1991-03-25 1992-03-24 Pharmaceutical preparation based on plasma proteins Expired - Fee Related CA2063872C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0065191A AT402789B (en) 1991-03-25 1991-03-25 PHARMACEUTICAL PREPARATION BASED ON PLASMA PROTEINS
ATA651/91 1991-03-25

Publications (2)

Publication Number Publication Date
CA2063872A1 true CA2063872A1 (en) 1992-09-26
CA2063872C CA2063872C (en) 1995-11-07

Family

ID=3496219

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002063872A Expired - Fee Related CA2063872C (en) 1991-03-25 1992-03-24 Pharmaceutical preparation based on plasma proteins

Country Status (7)

Country Link
EP (1) EP0506651B1 (en)
JP (1) JPH0570370A (en)
AT (2) AT402789B (en)
CA (1) CA2063872C (en)
DE (1) DE59207358D1 (en)
FI (1) FI107779B (en)
HU (1) HU214059B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5808000A (en) * 1994-07-14 1998-09-15 Immuno Aktiengesellschaft Virus-safe monomeric human immunoglobulin A and methods for its production
US6414125B1 (en) 1997-02-04 2002-07-02 Baxter Aktiengesellschaft Method of chromatographically purifying or fractionating, respectively, von Willebrand factor from a VWF-containing starting material

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE182793T1 (en) * 1994-02-18 1999-08-15 Immuno Ag COMPOSITION AND METHOD FOR PREVENTING AND TREATING INFLAMMATION WITH IMMUNOGLOBIN A
DE19600939C1 (en) 1996-01-12 1997-08-28 Immuno Ag Procedure for the separation of IgG and IgA
EP0920331A1 (en) * 1996-08-12 1999-06-09 A+ Science Invest AB Treatment and prevention of infections, inflammations and/or tumours with lactoferrin and/or lactoferricin
AT405135B (en) * 1997-01-17 1999-05-25 Immuno Ag PREPARATION COMPREHENSIVE THIOL GROUP-PROTEINS
AT407159B (en) * 1997-06-13 2001-01-25 Immuno Ag METHOD FOR DEPOSITING VIRALS AND MOLECULAR PATHOGENS FROM A BIOLOGICAL MATERIAL
AT410218B (en) 1999-08-20 2003-03-25 Baxter Ag METHOD FOR PRODUCING A QUALITY-ASSURED POOL OF BIOLOGICAL SAMPLES
WO2009143453A2 (en) * 2008-05-23 2009-11-26 The Lauridsen Group, Inc. Methods and compositions for reducing lung inflammation in an animal

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5837285B2 (en) * 1975-05-29 1983-08-15 カブシキガイシヤ ミドリジユウジ It is very difficult to understand the situation.
JPS5653623A (en) * 1979-10-09 1981-05-13 Mochida Pharmaceut Co Ltd Remedy for allergic disease
CS248954B1 (en) * 1983-02-10 1987-03-12 Alfred Stachy Mixture of immunoglobulins types igg,iga,igm and transferrin for intravenous and intraperitoneal application
CS242310B1 (en) * 1983-02-22 1986-04-17 Alfred Stachy Ig-7s or igg,iga,igm containing agent for external use
JPS59190922A (en) * 1983-04-12 1984-10-29 Green Cross Corp:The Remedy and preventive for inflammation
CS249222B1 (en) * 1985-02-08 1987-03-12 Alfred Stachy Mixture of ceruloplasmin,transferrin,igc,iga,igm-immunoglobulins for intravenous,intraperitoneal and intrathecal application
CS249225B1 (en) * 1985-02-12 1987-03-12 Alfred Stachy Mixture of ceruloplasmin and transferrin with 7 s immunoglubulins or igg,iga,igm immunoglubulins for mucosa application
CS260162B1 (en) * 1985-04-29 1988-12-15 Alfred Stachy Mixture of ceruloplasmin,transferrin,secretory iga and serous immunoglubulins igg,iga for application on mucosa of gastrointestinal tract
DE3844667A1 (en) * 1988-12-15 1990-06-21 Nitsche Dietrich Use of transferrin for controlling the toxic effect of endotoxin in endotoxinaemia
DE3842143A1 (en) * 1988-12-15 1990-06-21 Nitsche Dietrich USE OF TRANSFERRIN FOR ENDOTOXIN NEUTRALIZATION

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5808000A (en) * 1994-07-14 1998-09-15 Immuno Aktiengesellschaft Virus-safe monomeric human immunoglobulin A and methods for its production
US6414125B1 (en) 1997-02-04 2002-07-02 Baxter Aktiengesellschaft Method of chromatographically purifying or fractionating, respectively, von Willebrand factor from a VWF-containing starting material

Also Published As

Publication number Publication date
HUT60920A (en) 1992-11-30
CA2063872C (en) 1995-11-07
HU9200925D0 (en) 1992-05-28
FI921309A0 (en) 1992-03-25
FI107779B (en) 2001-10-15
FI921309A (en) 1992-09-26
JPH0570370A (en) 1993-03-23
EP0506651B1 (en) 1996-10-16
DE59207358D1 (en) 1996-11-21
HU214059B (en) 1997-12-29
ATE144148T1 (en) 1996-11-15
AT402789B (en) 1997-08-25
EP0506651A3 (en) 1993-04-14
ATA65191A (en) 1997-01-15
EP0506651A2 (en) 1992-09-30

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed