CA2061061A1 - Blockage of coenzyme a-independent transacylase activity as a method to inhibit lipid mediator production - Google Patents

Blockage of coenzyme a-independent transacylase activity as a method to inhibit lipid mediator production

Info

Publication number
CA2061061A1
CA2061061A1 CA 2061061 CA2061061A CA2061061A1 CA 2061061 A1 CA2061061 A1 CA 2061061A1 CA 2061061 CA2061061 CA 2061061 CA 2061061 A CA2061061 A CA 2061061A CA 2061061 A1 CA2061061 A1 CA 2061061A1
Authority
CA
Canada
Prior art keywords
coenzyme
blockage
lipid mediator
inhibit lipid
mediator production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2061061
Other languages
French (fr)
Other versions
CA2061061C (en
Inventor
Floyd H. Chilton
James David Winkler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of CA2061061A1 publication Critical patent/CA2061061A1/en
Application granted granted Critical
Publication of CA2061061C publication Critical patent/CA2061061C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

Coenzyme A-independent transacylase is required for the synthesis of arachidonic acid, arachidonic acid metabolites and platelet activation factor. Blocking of this enzyme inhibits the production of inflammatory mediators.
CA 2061061 1992-02-11 1992-02-12 Blockage of coenzyme a-independent transacylase activity as a method to inhibit lipid mediator production Expired - Fee Related CA2061061C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83385092A 1992-02-11 1992-02-11
US833,850 1992-02-11

Publications (2)

Publication Number Publication Date
CA2061061A1 true CA2061061A1 (en) 1993-08-12
CA2061061C CA2061061C (en) 2005-12-06

Family

ID=25265437

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2061061 Expired - Fee Related CA2061061C (en) 1992-02-11 1992-02-12 Blockage of coenzyme a-independent transacylase activity as a method to inhibit lipid mediator production

Country Status (1)

Country Link
CA (1) CA2061061C (en)

Also Published As

Publication number Publication date
CA2061061C (en) 2005-12-06

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