CA2054451A1 - Process for cleavage of esters during the production of cephalosporins - Google Patents

Process for cleavage of esters during the production of cephalosporins

Info

Publication number
CA2054451A1
CA2054451A1 CA002054451A CA2054451A CA2054451A1 CA 2054451 A1 CA2054451 A1 CA 2054451A1 CA 002054451 A CA002054451 A CA 002054451A CA 2054451 A CA2054451 A CA 2054451A CA 2054451 A1 CA2054451 A1 CA 2054451A1
Authority
CA
Canada
Prior art keywords
amino
formula
methyl
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002054451A
Other languages
English (en)
French (fr)
Inventor
William B. Blanchard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2054451A1 publication Critical patent/CA2054451A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002054451A 1990-11-05 1991-10-29 Process for cleavage of esters during the production of cephalosporins Abandoned CA2054451A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/608,772 1990-11-05
US07/608,772 US5095107A (en) 1990-11-05 1990-11-05 Process for cleavage of esters during the production of cephalosporins

Publications (1)

Publication Number Publication Date
CA2054451A1 true CA2054451A1 (en) 1992-05-06

Family

ID=24437931

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002054451A Abandoned CA2054451A1 (en) 1990-11-05 1991-10-29 Process for cleavage of esters during the production of cephalosporins

Country Status (11)

Country Link
US (1) US5095107A (Direct)
EP (1) EP0485103A3 (Direct)
JP (1) JPH04273875A (Direct)
KR (1) KR920009821A (Direct)
BR (1) BR9104802A (Direct)
CA (1) CA2054451A1 (Direct)
HU (1) HU209303B (Direct)
IE (1) IE913846A1 (Direct)
IL (1) IL99877A (Direct)
MX (1) MX9101921A (Direct)
TW (1) TW238310B (Direct)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239068A (en) * 1987-07-31 1993-08-24 Eli Lilly And Company Bicyclic β-lactam antibiotics
US5142039A (en) * 1987-07-31 1992-08-25 Eli Lilly And Company β-lactam antibiotics
US5302711A (en) * 1992-02-18 1994-04-12 Eli Lilly And Company Ester cleavage process for use with β-lactams
US5521307A (en) * 1992-02-18 1996-05-28 Eli Lilly And Company Methods and compounds for the preparation of carbacephems
IT1271404B (it) * 1993-08-09 1997-05-28 Hi Chem S P A Derivati ossimici dell'acido formilfenilacetamido-cefalosporanico
US5604222A (en) 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
WO1995035020A2 (en) * 1994-07-22 1995-12-28 Antibioticos S.P.A. Glutaryl 7-aca derivatives and processes for obtaining them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1546757A (en) * 1975-04-10 1979-05-31 Lilly Industries Ltd Crystalline cephalosporin salts
US5043439A (en) * 1990-03-08 1991-08-27 Bristol-Myers Squibb Company Process for production of cephalosporins

Also Published As

Publication number Publication date
IL99877A (en) 1997-04-15
HU209303B (en) 1994-04-28
KR920009821A (ko) 1992-06-25
MX9101921A (es) 1992-07-08
US5095107A (en) 1992-03-10
HUT59686A (en) 1992-06-29
IL99877A0 (en) 1992-08-18
BR9104802A (pt) 1992-09-15
HU913464D0 (en) 1992-01-28
EP0485103A2 (en) 1992-05-13
TW238310B (Direct) 1995-01-11
IE913846A1 (en) 1992-05-22
JPH04273875A (ja) 1992-09-30
EP0485103A3 (en) 1992-09-16

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Legal Events

Date Code Title Description
FZDE Discontinued