CA2045593A1 - Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans - Google Patents
Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humansInfo
- Publication number
- CA2045593A1 CA2045593A1 CA2045593A CA2045593A CA2045593A1 CA 2045593 A1 CA2045593 A1 CA 2045593A1 CA 2045593 A CA2045593 A CA 2045593A CA 2045593 A CA2045593 A CA 2045593A CA 2045593 A1 CA2045593 A1 CA 2045593A1
- Authority
- CA
- Canada
- Prior art keywords
- treatment
- humans
- derivatives
- malignant tumours
- benzopyrone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000011510 cancer Diseases 0.000 title abstract 2
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical class C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 title abstract 2
- 241000282414 Homo sapiens Species 0.000 abstract 2
- 208000003174 Brain Neoplasms Diseases 0.000 abstract 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000006265 Renal cell carcinoma Diseases 0.000 abstract 1
- 230000009422 growth inhibiting effect Effects 0.000 abstract 1
- 201000005296 lung carcinoma Diseases 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 210000002307 prostate Anatomy 0.000 abstract 1
- 201000001514 prostate carcinoma Diseases 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
- 201000000849 skin cancer Diseases 0.000 abstract 1
- 201000008261 skin carcinoma Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Monitoring And Testing Of Nuclear Reactors (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to the use of 1,2-benzopyrone derivatives for the treatment of malignant tumors in human beings. The derivatives used according to the invention are suitable for both preventive and also therapeutic treatment and they display in particular growth-inhibiting effect vis-à-vis brain-tumor cells and cells from human renal, prostate, skin or lung carcinomas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP3938902.2 | 1989-11-24 | ||
| DE3938902A DE3938902C1 (en) | 1989-11-24 | 1989-11-24 | |
| PCT/EP1990/002003 WO1991007959A1 (en) | 1989-11-24 | 1990-11-23 | Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2045593A1 true CA2045593A1 (en) | 1991-05-25 |
| CA2045593C CA2045593C (en) | 2000-09-05 |
Family
ID=6394102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002045593A Expired - Lifetime CA2045593C (en) | 1989-11-24 | 1990-11-23 | Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0455769B1 (en) |
| JP (1) | JP3053645B2 (en) |
| KR (1) | KR0177821B1 (en) |
| AT (1) | ATE128354T1 (en) |
| AU (1) | AU6739690A (en) |
| BR (1) | BR9007080A (en) |
| CA (1) | CA2045593C (en) |
| DE (2) | DE3938902C1 (en) |
| DK (1) | DK0455769T3 (en) |
| FI (1) | FI913531A0 (en) |
| WO (1) | WO1991007959A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2822379B1 (en) * | 2001-03-20 | 2007-06-15 | Sederma Sa | COSMETIC AND DERMOPHARMACEUTICAL COMPOSITIONS CONTAINING UMBELLIFERONE |
| US7148252B2 (en) * | 2001-10-03 | 2006-12-12 | Signal Pharmaceuticals, Llc | Use of benzopyranones for treating or preventing a primary brain cancer or a brain metastasis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5096887A (en) * | 1984-03-01 | 1992-03-17 | Lamorna Investments Proprietary Limited | Treatment of high protein oedemas |
-
1989
- 1989-11-24 DE DE3938902A patent/DE3938902C1/de not_active Expired - Lifetime
-
1990
- 1990-11-23 WO PCT/EP1990/002003 patent/WO1991007959A1/en active IP Right Grant
- 1990-11-23 DE DE59009724T patent/DE59009724D1/en not_active Expired - Fee Related
- 1990-11-23 BR BR909007080A patent/BR9007080A/en not_active Application Discontinuation
- 1990-11-23 JP JP2515771A patent/JP3053645B2/en not_active Expired - Fee Related
- 1990-11-23 CA CA002045593A patent/CA2045593C/en not_active Expired - Lifetime
- 1990-11-23 DK DK90917032.6T patent/DK0455769T3/en active
- 1990-11-23 AU AU67396/90A patent/AU6739690A/en not_active Abandoned
- 1990-11-23 EP EP90917032A patent/EP0455769B1/en not_active Expired - Lifetime
- 1990-11-23 AT AT90917032T patent/ATE128354T1/en not_active IP Right Cessation
-
1991
- 1991-07-22 KR KR1019910700768A patent/KR0177821B1/en not_active IP Right Cessation
- 1991-07-23 FI FI913531A patent/FI913531A0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991007959A1 (en) | 1991-06-13 |
| KR920700636A (en) | 1992-08-10 |
| DE59009724D1 (en) | 1995-11-02 |
| ATE128354T1 (en) | 1995-10-15 |
| DK0455769T3 (en) | 1996-02-05 |
| JP3053645B2 (en) | 2000-06-19 |
| CA2045593C (en) | 2000-09-05 |
| JPH04505020A (en) | 1992-09-03 |
| BR9007080A (en) | 1991-12-24 |
| EP0455769B1 (en) | 1995-09-27 |
| KR0177821B1 (en) | 1999-03-20 |
| EP0455769A1 (en) | 1991-11-13 |
| DE3938902C1 (en) | 1991-05-08 |
| AU6739690A (en) | 1991-06-26 |
| FI913531A0 (en) | 1991-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |