CA2045593A1 - Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans - Google Patents

Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans

Info

Publication number
CA2045593A1
CA2045593A1 CA2045593A CA2045593A CA2045593A1 CA 2045593 A1 CA2045593 A1 CA 2045593A1 CA 2045593 A CA2045593 A CA 2045593A CA 2045593 A CA2045593 A CA 2045593A CA 2045593 A1 CA2045593 A1 CA 2045593A1
Authority
CA
Canada
Prior art keywords
treatment
humans
derivatives
malignant tumours
benzopyrone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2045593A
Other languages
French (fr)
Other versions
CA2045593C (en
Inventor
Kurt Zanker
R. Douglas Thornes
Helga Stolze
Ernest Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PRAEVOMED GESELLSCHAFT fur MEDIZINISCHE PRAVENTION MBH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2045593A1 publication Critical patent/CA2045593A1/en
Application granted granted Critical
Publication of CA2045593C publication Critical patent/CA2045593C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Monitoring And Testing Of Nuclear Reactors (AREA)
  • External Artificial Organs (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to the use of 1,2-benzopyrone derivatives for the treatment of malignant tumors in human beings. The derivatives used according to the invention are suitable for both preventive and also therapeutic treatment and they display in particular growth-inhibiting effect vis-à-vis brain-tumor cells and cells from human renal, prostate, skin or lung carcinomas.
CA002045593A 1989-11-24 1990-11-23 Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans Expired - Lifetime CA2045593C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP3938902.2 1989-11-24
DE3938902A DE3938902C1 (en) 1989-11-24 1989-11-24
PCT/EP1990/002003 WO1991007959A1 (en) 1989-11-24 1990-11-23 Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans

Publications (2)

Publication Number Publication Date
CA2045593A1 true CA2045593A1 (en) 1991-05-25
CA2045593C CA2045593C (en) 2000-09-05

Family

ID=6394102

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002045593A Expired - Lifetime CA2045593C (en) 1989-11-24 1990-11-23 Use of 1,2-benzopyrone derivatives for the treatment of malignant tumours in humans

Country Status (11)

Country Link
EP (1) EP0455769B1 (en)
JP (1) JP3053645B2 (en)
KR (1) KR0177821B1 (en)
AT (1) ATE128354T1 (en)
AU (1) AU6739690A (en)
BR (1) BR9007080A (en)
CA (1) CA2045593C (en)
DE (2) DE3938902C1 (en)
DK (1) DK0455769T3 (en)
FI (1) FI913531A0 (en)
WO (1) WO1991007959A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2822379B1 (en) * 2001-03-20 2007-06-15 Sederma Sa COSMETIC AND DERMOPHARMACEUTICAL COMPOSITIONS CONTAINING UMBELLIFERONE
US7148252B2 (en) * 2001-10-03 2006-12-12 Signal Pharmaceuticals, Llc Use of benzopyranones for treating or preventing a primary brain cancer or a brain metastasis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575930B2 (en) * 1984-03-01 1988-08-11 Hamilton Laboratories Pty. Ltd. Treatment of high protein oedemas in animals

Also Published As

Publication number Publication date
DK0455769T3 (en) 1996-02-05
DE3938902C1 (en) 1991-05-08
BR9007080A (en) 1991-12-24
JP3053645B2 (en) 2000-06-19
EP0455769A1 (en) 1991-11-13
KR0177821B1 (en) 1999-03-20
WO1991007959A1 (en) 1991-06-13
FI913531A7 (en) 1991-07-23
KR920700636A (en) 1992-08-10
FI913531A0 (en) 1991-07-23
ATE128354T1 (en) 1995-10-15
EP0455769B1 (en) 1995-09-27
DE59009724D1 (en) 1995-11-02
JPH04505020A (en) 1992-09-03
AU6739690A (en) 1991-06-26
CA2045593C (en) 2000-09-05

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry