CA2042994A1 - Iontophoretic delivery device - Google Patents
Iontophoretic delivery deviceInfo
- Publication number
- CA2042994A1 CA2042994A1 CA 2042994 CA2042994A CA2042994A1 CA 2042994 A1 CA2042994 A1 CA 2042994A1 CA 2042994 CA2042994 CA 2042994 CA 2042994 A CA2042994 A CA 2042994A CA 2042994 A1 CA2042994 A1 CA 2042994A1
- Authority
- CA
- Canada
- Prior art keywords
- agent
- reservoir
- isoelectric point
- delivery device
- electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Electrotherapy Devices (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
An iontophoretic agent delivery device adapted to transdermally deliver an ionic agent, and a method of using same, are provided. The device has first and second electrodes connected to a source of electrical power. The first electrode is associated with a first agent reservoir and the second electrode is associated with a second agent reservoir. The device is adapted to deliver an agent, the agent having an isoelectric point at a specified pH, from both of the agent reservoirs simultaneously. This is accomplished by adjusting the pH of the first reservoir to a level above the isoelectric point of the agent while adjusting the pH of the second agent reservoir to a level below the isoelectric point. The device and method are particularly useful in iontophoretically delivering amino acids, polypeptides and proteins.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60028490A | 1990-10-17 | 1990-10-17 | |
US07/600,284 | 1990-10-17 | ||
US70344291A | 1991-05-20 | 1991-05-20 | |
US07/703,442 | 1991-05-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2042994A1 true CA2042994A1 (en) | 1992-04-18 |
CA2042994C CA2042994C (en) | 2004-08-03 |
Family
ID=27083561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2042994 Expired - Lifetime CA2042994C (en) | 1990-10-17 | 1991-05-21 | Iontophoretic delivery device |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2042994C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1138345A2 (en) | 1993-09-22 | 2001-10-04 | Hisamitsu Pharmaceutical Co., Inc. | A matrix for iontophoreses |
-
1991
- 1991-05-21 CA CA 2042994 patent/CA2042994C/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1138345A2 (en) | 1993-09-22 | 2001-10-04 | Hisamitsu Pharmaceutical Co., Inc. | A matrix for iontophoreses |
Also Published As
Publication number | Publication date |
---|---|
CA2042994C (en) | 2004-08-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5006108A (en) | Apparatus for iontophoretic drug delivery | |
AU694371B2 (en) | Electrotransport agent delivery method and apparatus | |
US5697896A (en) | Electrotransport delivery device | |
JP3779240B2 (en) | A method to reduce the effective electrical capacity of the power source required to drive the iontophoretic active agent administration system. | |
DE69624109T2 (en) | DEVICE FOR IONTOPHORETIC ADMINISTRATION OF MEDICINES WITH VOLTAGE Raising Circuit | |
CA2056015A1 (en) | Device and method for renewing electrodes during iontophoresis | |
EP0904801A3 (en) | Method of detecting events or conditions in an iontophoretic drug delivery system | |
AU1586692A (en) | Iontophoretic delivery device and method of making same | |
CA2001444A1 (en) | Iontophoresis electrode | |
CA2044791A1 (en) | Myocardial Iontophoresis | |
EP0752898A1 (en) | Reduction of skin irritation during electrotransport delivery | |
FI915878A0 (en) | Method and apparatus for electrically treating an electrolyte solution | |
US20040186417A1 (en) | Electrotransport agent delivery apparatus | |
DE69512083D1 (en) | DEVICE FOR INCREASING THE ACTIVE SUBSTANCE ADMINISTRATION BY ELECTRO TRANSPORT | |
US5310403A (en) | Iontophoretic drug delivery device and circuit therefor | |
CA2314929C (en) | Regulator with artificial load to maintain regulated delivery | |
AU564822B2 (en) | Apparatus to detect electrically low resistance point of skin and apply stimulus the reto | |
CA2042994A1 (en) | Iontophoretic delivery device | |
CA2247681A1 (en) | Methods for implementing current delivery profiles used in an iontophoretic system | |
JPH0447460U (en) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |