CA2042994A1 - Iontophoretic delivery device - Google Patents

Iontophoretic delivery device

Info

Publication number
CA2042994A1
CA2042994A1 CA 2042994 CA2042994A CA2042994A1 CA 2042994 A1 CA2042994 A1 CA 2042994A1 CA 2042994 CA2042994 CA 2042994 CA 2042994 A CA2042994 A CA 2042994A CA 2042994 A1 CA2042994 A1 CA 2042994A1
Authority
CA
Canada
Prior art keywords
agent
reservoir
isoelectric point
delivery device
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2042994
Other languages
French (fr)
Other versions
CA2042994C (en
Inventor
J. Richard Gyory
Ronald P. Haak
Felix Theeuwes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CA2042994A1 publication Critical patent/CA2042994A1/en
Application granted granted Critical
Publication of CA2042994C publication Critical patent/CA2042994C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Physical Or Chemical Processes And Apparatus (AREA)
  • Electrotherapy Devices (AREA)

Abstract

An iontophoretic agent delivery device adapted to transdermally deliver an ionic agent, and a method of using same, are provided. The device has first and second electrodes connected to a source of electrical power. The first electrode is associated with a first agent reservoir and the second electrode is associated with a second agent reservoir. The device is adapted to deliver an agent, the agent having an isoelectric point at a specified pH, from both of the agent reservoirs simultaneously. This is accomplished by adjusting the pH of the first reservoir to a level above the isoelectric point of the agent while adjusting the pH of the second agent reservoir to a level below the isoelectric point. The device and method are particularly useful in iontophoretically delivering amino acids, polypeptides and proteins.
CA 2042994 1990-10-17 1991-05-21 Iontophoretic delivery device Expired - Lifetime CA2042994C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60028490A 1990-10-17 1990-10-17
US07/600,284 1990-10-17
US70344291A 1991-05-20 1991-05-20
US07/703,442 1991-05-20

Publications (2)

Publication Number Publication Date
CA2042994A1 true CA2042994A1 (en) 1992-04-18
CA2042994C CA2042994C (en) 2004-08-03

Family

ID=27083561

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2042994 Expired - Lifetime CA2042994C (en) 1990-10-17 1991-05-21 Iontophoretic delivery device

Country Status (1)

Country Link
CA (1) CA2042994C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1138345A2 (en) 1993-09-22 2001-10-04 Hisamitsu Pharmaceutical Co., Inc. A matrix for iontophoreses

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1138345A2 (en) 1993-09-22 2001-10-04 Hisamitsu Pharmaceutical Co., Inc. A matrix for iontophoreses

Also Published As

Publication number Publication date
CA2042994C (en) 2004-08-03

Similar Documents

Publication Publication Date Title
US5006108A (en) Apparatus for iontophoretic drug delivery
CA2217711C (en) Electrotransport delivery with voltage boosting circuit
AU637674B2 (en) Method and apparatus for pulsed iontophoretic drug delivery
EP0615461B1 (en) Iontophoretic delivery device and power supply therefor
CA2022824C (en) Apparatus for an electrode and method used for iontophoresis
US6090095A (en) Electrotransport delivery device
CA2056015A1 (en) Device and method for renewing electrodes during iontophoresis
ES2065181T3 (en) IONTOPHORETICAL SUPPLY DEVICE AND PROCEDURE FOR ITS MANUFACTURE.
CA2001444A1 (en) Iontophoresis electrode
CA2044791A1 (en) Myocardial Iontophoresis
DE69634408D1 (en) DEVICE FOR IONTOPHORETIC ADMINISTRATION OF MEDICAMENTS WITH A CIRCUIT, EQUIPPED WITH A HIGH EFFICIENCY OF A DC GENERATOR
AU2123595A (en) Reduction of skin irritation during electrotransport delivery
NZ237636A (en) Iontophoretic drug delivery activated by electrode body contact
FI98511B (en) Method and apparatus for electrically treating an electrolytic solution
ATE184206T1 (en) DEVICE FOR INCREASE ADMINISTRATION OF ACTIVE INGREDIENTS BY ELECTRICAL TRANSPORT
US5310403A (en) Iontophoretic drug delivery device and circuit therefor
AU564822B2 (en) Apparatus to detect electrically low resistance point of skin and apply stimulus the reto
CA2042994A1 (en) Iontophoretic delivery device
CA2247681A1 (en) Methods for implementing current delivery profiles used in an iontophoretic system
JPH0380874A (en) Iontophoresis device
US7572252B1 (en) Electrotransport agent delivery method and apparatus

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry