CA2021179A1 - One-pot process for the preparation of .alpha.-l-aspartyl-l-phenylalaninemethyl ester hydrochloride - Google Patents

One-pot process for the preparation of .alpha.-l-aspartyl-l-phenylalaninemethyl ester hydrochloride

Info

Publication number
CA2021179A1
CA2021179A1 CA 2021179 CA2021179A CA2021179A1 CA 2021179 A1 CA2021179 A1 CA 2021179A1 CA 2021179 CA2021179 CA 2021179 CA 2021179 A CA2021179 A CA 2021179A CA 2021179 A1 CA2021179 A1 CA 2021179A1
Authority
CA
Canada
Prior art keywords
alpha
preparation
aspartyl
ester hydrochloride
pot process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2021179
Other languages
French (fr)
Other versions
CA2021179C (en
Inventor
John B. Hill
Yefim Gelman
Hugh L. Dryden, Jr.
Robert A. Erickson
Kuang Hsu
Mark R. Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nutrasweet Co
Original Assignee
Nutrasweet Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrasweet Co filed Critical Nutrasweet Co
Priority to CA002021179A priority Critical patent/CA2021179C/en
Publication of CA2021179A1 publication Critical patent/CA2021179A1/en
Application granted granted Critical
Publication of CA2021179C publication Critical patent/CA2021179C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

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  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)

Abstract

A one-pot process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride is disclosed (.alpha.-APM(HCl)). .alpha.-APH(HCl) is an intermediate in the preparation of aspartame.
CA002021179A 1990-07-13 1990-07-13 One-pot process for the preparation of .alpha.-l-aspartyl-l-phenylalaninemethyl ester hydrochloride Expired - Fee Related CA2021179C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002021179A CA2021179C (en) 1990-07-13 1990-07-13 One-pot process for the preparation of .alpha.-l-aspartyl-l-phenylalaninemethyl ester hydrochloride

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002021179A CA2021179C (en) 1990-07-13 1990-07-13 One-pot process for the preparation of .alpha.-l-aspartyl-l-phenylalaninemethyl ester hydrochloride

Publications (2)

Publication Number Publication Date
CA2021179A1 true CA2021179A1 (en) 1992-01-14
CA2021179C CA2021179C (en) 1999-01-19

Family

ID=4145477

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002021179A Expired - Fee Related CA2021179C (en) 1990-07-13 1990-07-13 One-pot process for the preparation of .alpha.-l-aspartyl-l-phenylalaninemethyl ester hydrochloride

Country Status (1)

Country Link
CA (1) CA2021179C (en)

Also Published As

Publication number Publication date
CA2021179C (en) 1999-01-19

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Legal Events

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EEER Examination request
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MKLA Lapsed

Effective date: 20020715