CA2015111A1 - New binary dispensor for the application of fluids, semi-fluids or semi-solids - Google Patents

New binary dispensor for the application of fluids, semi-fluids or semi-solids

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Publication number
CA2015111A1
CA2015111A1 CA 2015111 CA2015111A CA2015111A1 CA 2015111 A1 CA2015111 A1 CA 2015111A1 CA 2015111 CA2015111 CA 2015111 CA 2015111 A CA2015111 A CA 2015111A CA 2015111 A1 CA2015111 A1 CA 2015111A1
Authority
CA
Canada
Prior art keywords
substance
concentration
grams
benzoyl peroxide
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2015111
Other languages
French (fr)
Inventor
Tom Y. Woo
Janis P. Campbell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA 2015111 priority Critical patent/CA2015111A1/en
Publication of CA2015111A1 publication Critical patent/CA2015111A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ABSTRACT:
A unique "binary dispenser" for housing and applying various substances to various surfaces is proposed. This device is used as a means for the application of various substances (such as, but not limited to, liquids, semi-liquids, semi-solids, gels, ointments, lotions, creams, suspensions, solutions) to various surfaces (such as, but not limited to, biologic surfaces such as hair, skin or nails or to any non-biologic surface such as any nonbiologic surface).
Currently, most if not all, substances (biologic and non-biologic agents) are applied via a container (such as a tube, bottle or dispensor) which has a single chamber which houses the substance.
This device involves the use of an object, such as but not limited to, a container, tube, dispensor, bottle, or other such device which has two or more separate chambers, each containing a separate different substance.

Description

2 ~
Psg~ 5 FIELD OF INVENTION:
The pre~ent lnventlon rel~te~ to ~ ~in~ry device whLch i~
used as a means to apply an effective am~unt of variou~ substances, comprl~ing, ~ut nat llmited to, ~laloylc~lly ~ctlve a~ents (such ~M medlclnes, faod~ ar co~metlc sgent~) or non-biologlcally ~ctlve agenta (such aa glues, sha~poo~ having a de3ired effect on ~ur~ce~ comprialng, ~ut not limlte~ t~, blologlc surf~ces or nan-~lologlc inert ~ur~Qces.

BACK~OUN~ OF INVENTION:
The term "skin" 18 used in the broad conte~t ~ithln to include ~ny conditian he lt normal ar sbnorm~l o~ the ~kin, h~lr, nsll~
ar mucou~ membranes.

A contslner i~ u~ed ln the cantext wlthin thl~ p~tent ~pplicatlon to denote any object ~hich can house any ~ubstance or sub~tances camprl~Lng a~ but not li~lted ta, ~loloylcslly ~ctlve sgent or ~gent~ ar non-bialo~icslly ~ctlve agent or ~gents. The term "devlce"
is u~ed to descrlbe the preaent lnvention which houses any sub~tance.
The devlce may be B contalner such a~, ~ut not llmlted to, B tu~e, hbttle ~r ~ny ather di~pen~or. The devlce'~ compa~ltlon m~y ~e camprlsed o ~ny m~terial lncluding, but nnt li~ited to, cerqmlc, pla~tic~ ~teel, ru~*r, met~l or paper.

The devlc~ msy ~ emptled by the ~ctlan of yrsvlty, or pump, ~quee~in~ the devlce or ~ny other mechsnl~m to dellver ar ~dmlnlstar th0 cont~nt~.

~urrently mediain~l ~nd co4~Aetla ~gentB u~ed In the treflt~ent oi~

, . . . . .
.. . ..

, ,, . . . - , : . , , . - ~ - . , :

2 ~
P~ge 6 skin conditions (ond other internal medical conditions) are delivered to the skln u~lng a cont~iner whlch h~ ~ cavi~y within lt. Thht la to say that there la ~ alngle cont~lner whlch ha~
only one 3ubat~nce whlch is to be ad~iniRtered. The cont~iner csn be in the for~ o h tube or bottle. ~ulte ~requently two or ~ore medlclnal or coAmetlc ~ubstances cannot be packaged ln the ~ame contalner due to ~ubat~nce to subAtance lnteractlona which can effect the stablllty o~ the 3ub~t6nces utill~ed, can c3u~e undue drug reactlo~s or msy cau~e degrad~tion, etc., of th*
subat~nces. Thi~ invention refera to the uae of ~ device whlch ha~ one or more dlvldera ln lt thereby de~lnlng two or ~sre chambers wlthln the device. The dlvlder ~or divldera3 ~eparate and deflne the two (or more) cha~bers thereby keeping the two (or more~ preparQtlona ~ephrate. Thie would ~nsure th~t the ~u~tance~
wlthln e~ch chamher wo~ld not lnter~ct wlth e~ch other in an adverae way.

A~ an exa~ple toplcal benzoyl pero~ldes (theropeutlc agents for tre~tment o acne ) ~r* not to be ~i~ed with toplcal antlhiotlca d~e to ~t~blllty pro~l~m~ hnd re~ultent degrad~tion of both benzoyl peroxide ~nd the antlbiotlc product. In u~lng these two lngredlent-in ~ d*vlce whlch ha~ two ~epar~te ch~mberA, the ~ntlblotlc pr~p~ratlon can be lns~rt*d lnto one cha~ber and the ben~oyl peroxlde preparatlon ln the other, thla contalner ollowa for the ~imultdn*ou~ ~r ~equentlsl appllc~tlon o~ these two prepar~tlon~ to b~ dppll~d t~ the ~kln. Thi~ d~vl~e ce~prlaad a ~ln~ onvenlent cont~ln~r to bo u~ed for the ~ppll~otion to two aop~r~t~ aubatancea ` ' '' , ' '.

. .

. . : , ,. ,: ~
, P~ge 7 aa oppo~ed to two separate container3 each wlth their own preparatlon.

Other e~amples of substance~ which carl be u~ed in thi~ device with two aep~r~te chamber~ are, ~but not limlted to~:
) Tretinoln - Hydroq~inone (b) TretinoLn - topical antlblotlc 2. ta) steroid creams - Urea ~b) aterold cre~ms - ~hllcyllc Acld (c) ~terbld crea~s - L~ctic Acld (d) ateroid cream~ - Pramoxlne (e) ~terold cre~m~ - Tretlnbin ~f) aterold cre~ma - Hydroqulnonea ~ ~g) aterold crea~ - Xetoconaz~le .~ ~h) sterold cre~ hntiblotic lno~ldll - Tretlnolc Acld : 4. Anthr~nol - sterold cre~m~
5. Tretlnoin - benzoyl peroxlde.
. Sha~poo - condltloner~
7. Nail po}l~h - n~ll pollah rembver 8. Co~metic ~gent - coa~etlc agent Although thia device gen0rally re~era to ~ contalner with two ch~mber~, thia device c~n ~lao comprl~e b~ two or more dlvldera whlh d~lne thre~ or more aep~r~te chhmbers ~nd theref~re u~e b thr~a or mor~ ~ep~r~te aubat~nce~.

: ,

Claims (86)

1. A device which is used as a means to contain or house various substances or preparations, the device comprising of one or more dividers within the device thereby delineating the device to contain two or more separate chambers.
2. The device of claim #1 wherein the chambers are of equal volume, size or dimension.
3. The device of claim #1 wherein the chambers are of unequal volume, size or dimension.
4. The device of claim #1 wherein the device contains two separate chambers, the opening for each chamber (in order to dispense the substances or preparations) may be located on opposite sides of the container; or may be located directly adjacent; or may be located any distance apart between opposite sides of the container to directly adjacent.
5. The device of claim #1 to be termed a "binary dispenser", "binary tube", "binary bottle", "binary container", and/or "binary device".
6. The device of claim #1 wherein the device contains three separate chambers, the opening for each chamber (in order to dispense the substances) may be located on opposite sides of the container; or may be located directly adjacent; or may be located any distance apart between opposite sides of the container to directly adjacent.
7. The device of claim #1 wherein the device contains a divider which is impermeable or semi-permeable to some or all of the substances in each chamber.
8. The device of claim #1 wherein the device contains four separate chambers. The opening for each chamber (in order to dispense the substances) may be located on opposite sides of the container; or may be located directly adjacent; or may be located any distance apart between opposite sides of the container to directly adjacent.
9. The device of claim #1 wherein the device is used as a means to contain any substances or preparations comprising of, but not limited to, biologically, chemically, electrically active or inert substances.
10. The device of claim #1 wherein the device is used as a means to contain substances or preparations comprising of, but not limited to, foods, cosmetics, or medicinal agents.
11. The device of claim #1 wherein the device is used as a means to contain preparations or substances which may be liquid, semi-solid or semi-liquid comprising of, but not limited to, either combination of or singly:
A - creams B - ointments C - suspensions D - solutions E - pastes F - gels G - incorporating an inert solid compound or compounds I - lotions J - semi-solid substances or preparations K - semi-liquid substances or preparations L - liquid substances or preparations
12. The device of claim #1 wherein the device is used as a means to contain substances or preparations for any use comprising of, but not limited to, use in any biologic system or systems such as, but not limited to, application in medical or non-medical disorders, or for use in any non-biological system or systems such as, but not limited to, inert or dynamic surfaces. This can include any liquid, semi-liquid, semi-solid or galenical form including, but not limited to, gel, cream, lotion, ointment suspension, solution, paste, or incorporating an inert compound.
13. The device of claim #1 wherein the device is used as a means to contain substances or preparations as is claimed in claim #9, wherein one preparation is a topical antibiotic (any topical antibiotic and in any concentration or amounts) and another preparation is a benzoyl peroxide (in any concentration or any amount), other substances or preparations may or may not accompany these two.
14. The device of claim #1 wherein the device is used as a means to contain preparations as is claimed in claim #9, wherein one preparation is a topical antibiotic (any topical antibiotic and in any concentration or amounts) and another preparation is a topical tretinoin (in any concentration or any amount), other substances or preparations may or may not accompany these two.
15. The device of claim #1 wherein the device is used as a means to contain preparations as is claimed in claim #9, wherein one preparation is a topical benzoyl peroxide (any benzoyl peroxide and in any concentration or amounts) and another preparation is a topical tretinoin (in any concentration or any amount), other substances or preparations may or may not accompany these two.
16. The device of claim #1 wherein the device is used as a means to contain substances or preparations for the treatment of cosmetic disorders such as, but not limited to, facial wrinkles, hyperpigmentation, dry skin, flaky skin, itchy skin.
17. The device of claim #1 wherein the device is used as a means to contain medications or agents utilized in treatment of dermatologic or nondermatologic diseases, disorders, or states of any nature depending on the preparation that is used in the dispenser.
18. The device of claim #1 wherein the device is used as a means to contain substances or preparations which are for non-biologic use comprising of, but not limited to, glues and epoxy.
19. The device of claim #1 wherein the device is used as a means to contain substances or preparations to be used to treat other biologic functions comprising of, but not limited to, shampoo and cream rinse.
20. The device of claim #1 wherein the device may be comprised of, but not limited to, glass, plastic, metal, ceramic, rubber, paper or any other material or any combination thereof.
21. The device of claim #1 wherein the device may be comprised of plastic materials.
22. The device of claim #1 wherein the device may be comprised of metal materials.
23. The device of claim #1 wherein the device may be comprised of glass materials.
24. The device of claim #1 wherein the device may be comprised of ceramic materials.
25. The device of claim #1 wherein the device may be comprised of rubber materials.
26. The device of claim #1 wherein the device may be comprised of paper materials.
27. The device of claim #1 wherein the device is used as a means to contain preparations for human use, inert or dynamic nonbiologic use, veterinarian application or other biological or non-biological uses.
28. The device of claim #1 wherein the device comprises of another opening and closing device which is used as a means to open and close the chambers within the device.
29. An opening and closing device as claimed in claim #27 above, wherein the opening and closing device is comprised of a single unit or is comprised of two or more separate units and is composed of any composition, comprising of, but not limited to, glass, ceramic, rubber, paper, metal, plastic or any other material.
30. The device of claim #1 wherein the device may be emptied by the action of gravity, squeezing the device, a pump, or any other mechanism to deliver or administer the contents.
31. The device of claim #1 wherein the pump or any other mechanism to administer the contents of the device is comprised of, but not limited to, ceramic, plastic, steel, rubber, metal, paper or any other material or any combination thereof.
32. The device of claim #1 wherein the pump or any other mechanism to administer the contents of the device is comprised of ceramic.
33. The device of claim #1 wherein the pump or any other mechanism to administer the contents of the device is comprised of plastic.
34. The device of claim #1 wherein the pump or any other mechanism to administer the contents of the device is comprised of metal.
35. The device of claim #1 wherein the pump or any other mechanism to administer the contents of the device is comprised of paper.
36. The device of claim #1 wherein the pump or any other mechanism to administer the contents of the device is comprised of rubber.
37. A method of applying substances or preparations to various surfaces administering an effective amount of substances or preparations compatible with a desired effect, the device which is used as a means of applying the substance or preparation is a device comprising of one or more dividers within the device thereby delineating the device to contain two or more separate chambers.
38. The method of claim #36 wherein the chambers are of equal volume, size or dimension.
39. The method of claim #36 wherein the chambers are of unequal volume, size or dimension.
40. The method of claim #36 wherein the device contains two separate chambers, the opening for each chamber (in order to dispense the substances or preparations) may be located on opposite sides of the container; or may be located directly adjacent; or may be located any distance apart between opposite sides of the container to directly adjacent.
41. The method of claim #36 wherein the device is to be termed a "binary dispenser", "binary tube", "binary bottle", "binary container" and/or "binary device".
42. The method of claim #36 wherein the device contains three separate chambers, the opening for each chamber (in order to dispense the substances) may be located on opposite sides of the container; or may be located directly adjacent; or may be located any distance apart between opposite sides of the container to directly adjacent.
43. The method of claim #36 wherein the device contains a divider which is impermeable or semi-permeable to some or all of the substances in each chamber.
44. The method of claim #36 wherein the device contains four separate chambers. The opening for each chamber (in order to dispense the substances) may be located on opposite sides of the container; or may be located directly adjacent; or may be located any distance apart between opposite sides of the container to directly adjacent.
45. The method of claim 336 wherein the device is used as a means to contain any substances or preparations comprising of, but not limited to, biologically, chemically, electrically active or inert substances.
46. The method of claim #36 wherein the device is used as a means to contain substances or preparations comprising of, but not limited to, foods, cosmetics or medicinal agents.
47. The method of claim #36 wherein the device is used as a means to contain preparations or substances which may be liquid, semi-solid or semi-liquid, comprising of, but not limited to, either combination of or singly:
A - creams B - ointments C - suspension D - solution E - paste F - gel G - incorporating an inert solid compounds.
I - lotion J - semi-solid substances or preparations K - semi-liquid substances or preparations L - liquid substances or preparations
48. The method of claim #36 wherein the device is used as a means to contain substances or preparations for any use comprising of, but not limited to, use in any biologic system or systems such as but not limited to, application in medical or non-medical disorders or for use in any non-biologlcal system or systems such as, but not limited to, inert or dynamic substances. This can include any semi-liquid, liquid, semi-solid or galenical form including, but not limited to, gel, cream, lotion, ointment suspension, solution, paste, or incorporating an inert compound.
49. The method of Claim #36 wherein the device is used as a means to contain substances or preparations as is claimed in claim #9, wherein one preparation is a topical antibiotic (any topical antibiotic and in any concentration or amounts) and another preparation is a benzoyl peroxide (in any concentration or any amount), other substances or preparations may or may not accompany these two.
50. The method of claim #36 wherein the device is used as a means to contain preparations as is claimed in claim #9 wherein one preparation is a total antibiotic (any topical antibiotic and in any concentration or amounts) and another preparation is a topical tretinoin (in any concentration or any amount), other substances or preparation may or may not accompany these two.
51. The method of claim #36 wherein the device is used as a means to contain substances or preparations for the treatment of cosmetic disorders such as, but not limited to, facial wrinkles.
hyperpigmentation, dry skin, flaky skin, itchy skin.
52. The method of claim #36 wherein the device is used to contain medication or agents utilized in treatment of dermatologic or nondermatologic disease, disorders or states on any nature depending on the preparation that is used on the dispenser.
53. the method of claim #36 wherein the device is used as a means to contain substances or preparations which are for non-biologic use comprising of, but not limited to, glues and epoxy.
54. The method of claim #36 where in the device is used as a means to containt substances or preparations to be used to threat other biologic functions comprising of , but not limited to, shampoo and cream rinse.
55. The method of claim #36 wherein the device may be comprised of, but not limited to, glass. plastic, metal, ceramic, rubber, paper or any other material or any combination thereof.
56. The method of claim #36 wherein the device may be comprised of plastic materials.
57. the method of claim #36 wherein the device may be comprised of metal material.
58. The method of claim #36 wherein the device may be comprised of glass materials.
59. The method of claim #36 wherein the device may be comprised of ceramic materials.
60. The method of claim #36 wherein the device may be comprised of rubber materials.
61. The method of claim #36 wherein the device may be comprised of paper materials.
62. The method of claim #36 wherein the device is used as a means to contain preparations for human use, inert or dynamic nonbiologic use, veterinarian application or other biological or non-biological uses.
63. The method of claim #36 wherein the device comprises of another opening and closing device which is used as a means to open and close the chambers within the device.
64. The method of claim #36 wherein the opening and closing device is comprised of a single unit or is comprised of two or more separate units and is composed of any composition, comprising of, but not limited to, glass, ceramic, metal, rubber, paper, plastic or any other material.
65. The method of claim #36 wherein the device may be emptied by the action of gravity, squeezing the device, a pump or any other mechanism to deliver or administer the contents.
66. The method of claim #36 wherein the pump or any other mechanism to administer the contents of the device is comprised of, but not limited to, ceramic, plastic, steel, rubber, metal, paper or any other material or any combination thereof.
67. The method of #36 wherein the pump or any other mechanism to administer the contents of the device is comprised of ceramic.
68. The method of claim #36 wherein the pump or any other mechanism to administer the contents of the device is comprised of plastic.
69. The method of claim #36 wherein the pump or any other mechanism to administer the contents of the device is comprised of metal.
70. the method of claim #36 wherein the pump or any other mechanism to administer the contents of the device is comprised of paper.
71. The method of claim #36 wherein the pump or any other mechanism to administer the contents of the device is comprised of rubber.
72. The device of claim #1 which is used as a means to apply substances or preparations wherein:
(a) at least one substance is erythtomycin or erythtomycin derivatives in a concentrations of 2% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams/100cc)
73. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams/100 cc)
74. The device of claim #1 which is used as a means to apply substances wherein;
(a) at least one substances is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl) peroxide derivative in a concentration of 5% (grams/100 cc)
75. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythtomycin or erythromycin derivative in a concentration of 5% (grams/100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of %5 (grams/100 cc)
76. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams/100 cc)
77. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams/100 cc)
78. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in concentration of 20% (grams/100 cc)
79. The device of claim #1 which is used as a means to apply substances wherein' (a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide derivative in a concentration of 20% (grams/100 cc)
80. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythtomycin or erythtomycin derivative in a concentration of 15 (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .01% (grams/100 cc)
81. The device of claim #1 which is used as a means to apply substances wherein:

(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .01% (grams/100 cc)
82. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .025% (grams/100 cc)
83. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substances is erythtomycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .025% (grams/100 cc)
84. the device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythtomycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/100 cc)
85. the device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythtomycin or erythromycis derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05 (grams/100 cc)
86. the device of claim #1 which is used as a means to apply substances wherein;
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 1 87. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is erythromycin or erythromycin (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 88. The device of claim #1 which is used as a means to apply substances or preparation wherein;
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 89. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 90. The device of claim #1 which used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 91. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 205 (grams/100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 92. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .025% (grams/100 cc) 93. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of 0.25% (grams/100 cc) 94. The device of claim #1 which is used as a means to apply substances wherein;
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of 0.255 (grams/100 cc) 95. The device of claim 31 which is used as a means to apply substances wherein;
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .025% (grams/100 cc) 96. the device of claim #1 which is used as a means to apply substances wherein;
(a) at least one substance is tretinoin in a concentration of 0.5% (grams/ 100 cc) 97. the device of claim #1 which is used as a means to apply substances wherein :
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/ 100 cc) 98. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (9grams/100 cc) (b) at least one substance is tretinoin in a concentration of 0.5% (grams/100 cc) 99. The device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams/ 100 cc) (b) at least one substance is tretinoin in a concentration of .05% ( grams/100 cc) 100. The device of claim #1 which is used a as a means to apply substances wherein:
(a) at least one substance is tretinoin in a concentration of derivative in a concentrations of 2.5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 101. the device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 102. the device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 103. the device of claim #1 which is used as a means to apply substances wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams/100 cc (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 104. The device of claim #1 which is used to apply substances wherein;
(a) at least one substance is a shampoo (b) at least one substance is a hair conditioner 105. The device of claim #1 which is used to apply substances wherein:
(a) at least one substance is a Tretinoin (b) at least one substance is a Hydroquinoine 106. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a Tretinoin (b) at least one substance is a topical antibiotic 107. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Urea 108. The device of claim 1 which is used to apply substances wherein:

(a) at least one substance is a steroid cream (b) at least one substance is a Salicylic Acid 109. The device of claim 1 which is used to apply substances wherein;
(a) at least one substance is a steroid cream (b) at least one substance is a Lactic Acid 110. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Pramoxine 111. The device of claim 1 which is used to apply substances wherein;
(a) at least one substance is a steroid cream (b) at least one substance is a Tretinoin 112. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Hydroquinone 113. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Ketoconazole 114. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a antibiotic 115. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is Minoxidil (b) at least one substance is Tretinoic Acid 116. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is Anthranol (b) at least one substance is a steroid cream 117. the device of claim 1 which is used to apply substances wherein:
(a) at least one substance is Tretinoin (b) at least one substance is benzoyl peroxide 118. The device of claim 1 which is used to apply substances wherein:
(a) at least one substance is a nail polish (b) at least one substance is a nail polish remover 119. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein;
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams/100 cc) 120. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams/100 cc) 121. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) 122. A preparation which is applied to various surfaces to obtain a desired effect is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) 123. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) 124. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams/100 cc) 125. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams per 100 cc) (b) at least one substance is benzoyl or benzyl peroxide derivative in a concentration of 20% (grams/100 cc) 126. A preparation which is applied to various surfaces to obtain a desired effect which is house in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams per 100 cc) (b) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams/100 cc) 127. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .01% (grams/100 cc) 128. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .01% (grams/100 cc) 129. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .025% (grams/100 cc) 130. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .025% (grams/100 cc) 131. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams. 100 cc) 132. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/100 cc) 133. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 1% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 134. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is erythromycin or erythromycin derivative in a concentration of 25 (grams/100 cc) (a) at least one substance is erythromycin or erythromycin derivative in a concentration of 2% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 135. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 136. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 137. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein;
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams per 100 0 (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 138. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzyl peroxide derivative in a concentration of 20% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .01% (grams/100 cc) 139. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .025% (grams/100 cc) 140. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .025% (grams/100 cc) 141. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .025% ( grams/100 cc) 142. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:

(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams per 100 cc) (b) at least one substance is tretinoin or tretinoin derivative in a concentration of .025% (grams/100 cc) 143. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/100 cc) 144. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/100 cc) 145. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/100 cc) 146. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .05% (grams/100 cc) 147. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 2.5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 148. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 5% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 149. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 10% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 150. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is benzoyl peroxide or benzoyl peroxide derivative in a concentration of 20% (grams/100 cc) (b) at least one substance is tretinoin in a concentration of .1% (grams/100 cc) 151. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a shampoo (b) at least one substance is a hair conditioner 152. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a Tretinoin (b) at least one substance is a Hydroquinoine 153. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a Tretinoin (b) at least one substance is a topical antibiotic 154. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Urea 155. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Salicylic Acid 156. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:

(a) at least one substance is a steroid cream (b) at least one substance is a Lactic Acid 157. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Pramoxine 158. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Tretinoin 159. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Hydroquinone 160. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a Ketoconazole 161. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:
(a) at least one substance is a steroid cream (b) at least one substance is a antibiotic 162. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device of claim 1, wherein:

(a) at least one substance is Minoxidil (b) at least one substance is Tretinoic Acid 163. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device to claim 1, wherein:
(a) at least one substance is Anthranol (b) at least one substance is a steroid cream 164. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device to claim 1, wherein:
(a) at least one substance is Tretinoin (b) at least one substance is benzoyl peroxide 165. A preparation which is applied to various surfaces to obtain a desired effect which is housed in a device to claim 1, wherein:
(a) at least one substance is a nail polish (b) at least one substance is a nail polish remover
CA 2015111 1990-04-23 1990-04-23 New binary dispensor for the application of fluids, semi-fluids or semi-solids Abandoned CA2015111A1 (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002133A2 (en) * 1997-07-08 1999-01-21 Dsm N.V. Topical application of a combination of benzoyl peroxide and a second active ingredient
WO2001091726A1 (en) * 2000-06-02 2001-12-06 Dermik International Holding Inc. Acne-treating composition
WO2002047662A3 (en) * 2000-12-12 2003-03-13 Imaginitive Res Associates Inc Antibiotic/benzoyl peroxide dispenser
WO2004064803A1 (en) * 2003-01-23 2004-08-05 Edko Trading And Representation Co. Ltd Topical pharmaceutical and/or cosmetic dispense systems
US6774100B2 (en) 2000-12-06 2004-08-10 Imaginative Research Associates, Inc. Anhydrous creams, lotions and gels
US7060732B2 (en) 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US9107844B2 (en) 2006-02-03 2015-08-18 Stiefel Laboratories Inc. Topical skin treating compositions

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002133A2 (en) * 1997-07-08 1999-01-21 Dsm N.V. Topical application of a combination of benzoyl peroxide and a second active ingredient
WO1999002133A3 (en) * 1997-07-08 1999-04-01 Gist Brocades Bv Topical application of a combination of benzoyl peroxide and a second active ingredient
US6448233B1 (en) 1997-07-08 2002-09-10 Cosmoferm B.V. Topical application of a combination of benzoyl peroxide and a second active ingredient
WO2001091726A1 (en) * 2000-06-02 2001-12-06 Dermik International Holding Inc. Acne-treating composition
US6774100B2 (en) 2000-12-06 2004-08-10 Imaginative Research Associates, Inc. Anhydrous creams, lotions and gels
WO2002047662A3 (en) * 2000-12-12 2003-03-13 Imaginitive Res Associates Inc Antibiotic/benzoyl peroxide dispenser
US7060732B2 (en) 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
WO2004064803A1 (en) * 2003-01-23 2004-08-05 Edko Trading And Representation Co. Ltd Topical pharmaceutical and/or cosmetic dispense systems
EA008813B1 (en) * 2003-01-23 2007-08-31 Эдко Трейдинг Энд Репрезентейшн Ко. Лтд. Topical pharmaceutical and/or cosmetic dispense systems
US9107844B2 (en) 2006-02-03 2015-08-18 Stiefel Laboratories Inc. Topical skin treating compositions

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