CA2008695A1 - Gene switch - Google Patents

Gene switch

Info

Publication number
CA2008695A1
CA2008695A1 CA2008695A CA2008695A CA2008695A1 CA 2008695 A1 CA2008695 A1 CA 2008695A1 CA 2008695 A CA2008695 A CA 2008695A CA 2008695 A CA2008695 A CA 2008695A CA 2008695 A1 CA2008695 A1 CA 2008695A1
Authority
CA
Canada
Prior art keywords
gene
gene switch
promoter sequence
inducer
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2008695A
Other languages
French (fr)
Other versions
CA2008695C (en
Inventor
Wolfgang Walter Schuch
Simon William Jonathan Bright
Ian George Bridges
Andrew James Greenland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Imperial Chemical Industries Plc
Wolfgang Walter Schuch
Simon William Jonathan Bright
Ian George Bridges
Andrew James Greenland
Zeneca Limited
Syngenta Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Plc, Wolfgang Walter Schuch, Simon William Jonathan Bright, Ian George Bridges, Andrew James Greenland, Zeneca Limited, Syngenta Limited filed Critical Imperial Chemical Industries Plc
Publication of CA2008695A1 publication Critical patent/CA2008695A1/en
Application granted granted Critical
Publication of CA2008695C publication Critical patent/CA2008695C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088—Glutathione transferase (2.5.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237—Externally regulated expression systems
    • C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Lock And Its Accessories (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1. A gene promoter sequence which responds to application of an exogenous chemical inducer such as one of the plant herbicide safeners is utilised as a gene switch to enable external control of expression of a gene placed under control of the promoter. A
specific example of the gene switch construct is the maize GSTII (glutathione-S-transferase isoform II) enzyme promoter sequence which is inducer by external application of the safener N,N-diallyl-2,2-dichloroacetamide.
CA002008695A 1989-01-26 1990-01-26 Gene switch Expired - Fee Related CA2008695C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898901673A GB8901673D0 (en) 1989-01-26 1989-01-26 Gene switch
GB8901673.7 1989-01-26

Publications (2)

Publication Number Publication Date
CA2008695A1 true CA2008695A1 (en) 1990-07-26
CA2008695C CA2008695C (en) 1999-03-16

Family

ID=10650613

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002008695A Expired - Fee Related CA2008695C (en) 1989-01-26 1990-01-26 Gene switch

Country Status (6)

Country Link
EP (1) EP0455667A1 (en)
AU (1) AU647016B2 (en)
CA (1) CA2008695C (en)
GB (1) GB8901673D0 (en)
WO (1) WO1990008826A1 (en)
ZA (1) ZA90604B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901677D0 (en) 1989-01-26 1989-03-15 Ici Plc Hybrid seed production
US5907086A (en) * 1991-05-01 1999-05-25 Pioneer Hi-Bred International, Inc. Plant promoter sequences
GB9114259D0 (en) * 1991-07-02 1991-08-21 Ici Plc Plant derived enzyme and dna sequences
AU2273392A (en) * 1991-07-11 1993-02-11 International Flower Developments Pty Ltd Genetic sequences encoding flavonoid pathway enzymes and uses therefor
DK0637339T3 (en) 1992-04-13 2001-12-03 Syngenta Ltd DNA constructs and plants in which they are incorporated
GB9223332D0 (en) * 1992-11-06 1992-12-23 Ici Plc Production of polyhydroxyalkanoate in plants
GB9223454D0 (en) * 1992-11-09 1992-12-23 Ici Plc Novel plants and processes for obtaining them
US6066456A (en) * 1993-12-30 2000-05-23 Zeneca Limited Plant-derived enzyme and DNA sequences and uses thereof
EG23907A (en) * 1994-08-01 2007-12-30 Delta & Pine Land Co Control of plant gene expression
US5723765A (en) * 1994-08-01 1998-03-03 Delta And Pine Land Co. Control of plant gene expression
TR200003861T2 (en) 1995-05-26 2001-04-20 Zeneca Limited A gene key that contains an ecdysone receptor.
US5859338A (en) * 1995-06-06 1999-01-12 California Institute Of Technology Plant clavata1 nucleic acids, transformed plants, and proteins
IL123686A0 (en) * 1995-09-22 1998-10-30 Zeneca Ltd Plant glutathione s-transferase promoters
US6610828B1 (en) 1996-05-24 2003-08-26 Syngenta Limited Heliothis ecdysone receptor
BR9811493A (en) * 1997-07-30 2000-09-19 Zeneca Ltd Genetic method for germination control
WO1999042598A2 (en) 1998-02-20 1999-08-26 Zeneca Limited Hybrid seed production
ES2624549T3 (en) 1998-04-08 2017-07-14 Commonwealth Scientific And Industrial Research Organisati Methods and means to obtain modified phenotypes
EP1029923A1 (en) 1999-01-27 2000-08-23 D.J. Van Der Have B.V. Method for conveying BNYVV resistance to sugar beet plants
AU782327C (en) 1999-12-16 2006-09-14 Cropdesign N.V. Optimized T-DNA transfer and vectors therefor
EP2119786A1 (en) 2008-05-13 2009-11-18 Expressive Research B.V. Increased production of health-promoting compounds in plants
US20130055471A1 (en) 2009-12-15 2013-02-28 Edwin Henricus Antonius HOLMAN Transgenic Ozone-Resistant Plants
NL2004624C2 (en) 2010-04-28 2011-11-01 Stichting Dienst Landbouwkundi A new glycosyltransferase protein and its role in the metabolism of phenylpropanoid volatiles in tomato.
EP3560329A1 (en) 2011-05-02 2019-10-30 Board of Regents of the University of Nebraska Plants with useful traits and related methods
US9612235B2 (en) 2012-04-05 2017-04-04 Koch Biological Solutions, Llc Herbicidal compound screening
US10767188B2 (en) 2013-09-25 2020-09-08 Nutech Ventures Methods and compositions for obtaining useful plant traits
CN110036114B (en) 2016-08-26 2023-09-29 勒萨弗尔公司 Enhanced itaconic acid production
EP3533878A1 (en) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Process for producing citramalic acid employing aspergillus

Also Published As

Publication number Publication date
WO1990008826A1 (en) 1990-08-09
EP0455667A1 (en) 1991-11-13
CA2008695C (en) 1999-03-16
AU4947690A (en) 1990-08-24
GB8901673D0 (en) 1989-03-15
ZA90604B (en) 1990-11-28
AU647016B2 (en) 1994-03-17

Similar Documents

Publication Publication Date Title
CA2008695A1 (en) Gene switch
AU2053888A (en) Balance mechanism of an industrial robot
DE69333980D1 (en) TRIGGER OF SENSITIVITY REACTIONS IN PLANTS
AU2885589A (en) Composition of anticoagulants
WO1990002801A3 (en) Plants transformed with a dna sequence from bacillus thuringiensis lethal to lepidoptera
EP1338199A3 (en) Herbicidal compositions
AU674378B2 (en) Use of 2-amino-6-A-propylamino-4,5,6, 7-tetrahydrobenzothiazole (pramipexol) as an anti-depressantdrug
WO1989001515A3 (en) Plants transformed with a dna sequence from bacillus thuringiensis
DE3469027D1 (en) Herbicidal sulfonylureas
AU6639590A (en) Sulphonated heterocyclic carboxamides as herbicides, growth regulators or fungicides
AU2989289A (en) A new class of pesticides comprising 1,4-bis-substituted-2,6,7-trioxabicyclo(2.2.2)octanes
AU4709889A (en) Recombinant dna expression vectors and dna compounds that encode isopenicillin n epimerase (racemase) activity
NZ334604A (en) A DNA molecule containing a baculovirus promoter operable linked to a coding sequnce for an insect-specific toxin; biological insect control agents comprising the altered baculovirus
AU7415387A (en) Imidazolesulfonamide derivatives and herbicides
EP0295233A3 (en) Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides
AU574857B2 (en) 4,6-dialkoxy pyridine-3(5)-(di) carboxylate compounds
CA2126602A1 (en) Herbicidal compositions
NZ235252A (en) Herbicidal composition containing both a chemical agent which facilitates bacterial infection of weeds and a bacterial plant pathogen; weed control method
BG102481A (en) New herbicidic compositions containing 4-benzoyloxazoles and akloniphene
AU527894B2 (en) Bis-penicillin esters of alkane diols
WO1988003922A3 (en) Thiophenesulfonamide herbicides
WO1995004719A1 (en) Substituted 4-carbamoyl pyrrolin-2-one and dihydrofuran-2-one derivatives and their use as pesticides
EP0316185A3 (en) N-cyanomethyl-2-pyridinone insecticides
WO1989000994A3 (en) Herbicidal sulfonamides
WO1989002700A3 (en) Herbicidal o-carbomethoxysulfonylureas

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed